Search Results - "Collerton, Joanna"
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Serum Thyroid Function, Mortality and Disability in Advanced Old Age: The Newcastle 85+ Study
Published in The journal of clinical endocrinology and metabolism (01-11-2016)“…Context: Perturbations in thyroid function are common in older individuals but their significance in the very old is not fully understood. Objective: This…”
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Losing the ability in activities of daily living in the oldest old: a hierarchic disability scale from the Newcastle 85+ study
Published in PloS one (15-02-2012)“…To investigate the order in which 85 year olds develop difficulty in performing a wide range of daily activities covering basic personal care, household care…”
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Engaging the oldest old in research: lessons from the Newcastle 85+ study
Published in BMC geriatrics (17-09-2010)“…Those aged 85 and over, the oldest old, are now the fastest growing sector of the population. Information on their health is essential to inform future…”
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A comparison of subjective and objective measures of physical activity from the Newcastle 85+ study
Published in Age and ageing (01-07-2015)“…Little is known about physical activity (PA) in the very old, the fastest growing age group in the population. We aimed to examine the convergent validity of…”
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The contribution of diseases to the male-female disability-survival paradox in the very old: results from the Newcastle 85+ study
Published in PloS one (07-02-2014)“…Explanations for the male-female disability-survival paradox - that woman live longer than men but with more disability - include sex differences in diseases…”
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Deconstructing Complex Multimorbidity in the Very Old: Findings from the Newcastle 85+ Study
Published in BioMed research international (01-01-2016)“…Objectives. To examine the extent and complexity of the morbidity burden in 85-year-olds; identify patterns within multimorbidity; and explore associations…”
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Improving retention of very old participants in longitudinal research: experiences from the Newcastle 85+ study
Published in PloS one (10-10-2014)“…People aged 85 and over are often excluded from research on the grounds of being difficult to recruit and problematic to retain. The Newcastle 85+ study…”
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The enduring effect of education-socioeconomic differences in disability trajectories from age 85 years in the Newcastle 85+ Study
Published in Archives of gerontology and geriatrics (01-05-2015)“…Highlights • Even at aged 85, four gender specific trajectories of disability are evident. • A disability-free trajectory is found in men only comprising 9% of…”
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Assessment of sleep and circadian rhythm disorders in the very old: the Newcastle 85+ Cohort Study
Published in Age and ageing (01-01-2014)“…to examine the association between subjective and objective measures of sleep and wake and other health parameters in a cohort of the very old. a…”
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Capability and dependency in the Newcastle 85+ cohort study. Projections of future care needs
Published in BMC geriatrics (04-05-2011)“…Little is known of the capabilities of the oldest old, the fastest growing age group in the population. We aimed to estimate capability and dependency in a…”
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Longitudinal changes in global and domain specific cognitive function in the very‐old: findings from the Newcastle 85+ Study
Published in International journal of geriatric psychiatry (01-02-2018)“…Objective Ageing is associated with changes in cognition in some, but not all domains. In young–old adults, defined as persons aged 65–84 years, baseline…”
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Prevalence of arthritis and joint pain in the oldest old: findings from the Newcastle 85+ Study
Published in Age and ageing (01-11-2011)“…Arthritis is a condition strongly associated with age, yet surprisingly few comprehensive studies to date have examined how arthritis affects the oldest old --…”
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The personal and health service impact of falls in 85 year olds: cross-sectional findings from the Newcastle 85+ cohort study
Published in PloS one (09-03-2012)“…Falls are common in older people and increase in prevalence with advancing old age. There is limited knowledge about their impact in those aged 85 years and…”
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The Newcastle 85+ study: biological, clinical and psychosocial factors associated with healthy ageing: study protocol
Published in BMC geriatrics (26-06-2007)“…The UK, like other developed countries, is experiencing a marked change in the age structure of its population characterised by increasing life expectancy and…”
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A Comparison of Computerized and Pencil-and-Paper Tasks in Assessing Cognitive Function in Community-Dwelling Older People in the Newcastle 85+ Pilot Study
Published in Journal of the American Geriatrics Society (JAGS) (01-10-2007)“…OBJECTIVES: To compare the acceptability and feasibility of computerized and pencil‐and‐paper tests of cognitive function in 85‐year‐old people. DESIGN: Group…”
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The Association between Diagnosed Glaucoma and Cataract and Cognitive Performance in very old People: Cross-sectional Findings from the Newcastle 85+ Study
Published in Ophthalmic epidemiology (01-04-2013)“…ABSTRACT Purpose: Common age-related eye diseases including glaucoma, cataract and age-related macular degeneration (AMD) have been proposed to be associated…”
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Reactive oxygen species production and mitochondrial dysfunction in white blood cells are not valid biomarkers of ageing in the very old
Published in PloS one (10-03-2014)“…Reliable and valid biomarkers of ageing (BoA) are needed to understand mechanisms, test interventions and predict the timing of adverse health events…”
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CMV-independent increase in CD27−CD28+ CD8+ EMRA T cells is inversely related to mortality in octogenarians
Published in npj aging and mechanisms of disease (2020)“…Cytomegalovirus (CMV) seropositivity in adults has been linked to increased cardiovascular disease burden. Phenotypically, CMV infection leads to an inflated…”
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Age-related frailty and its association with biological markers of ageing
Published in BMC medicine (13-07-2015)“…The relationship between age-related frailty and the underlying processes that drive changes in health is currently unclear. Considered individually, most…”
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Frailty and the role of inflammation, immunosenescence and cellular ageing in the very old: Cross-sectional findings from the Newcastle 85+ Study
Published in Mechanisms of ageing and development (01-06-2012)“…► We confirm the importance of inflammation in frailty in a very old population. ► Limited evidence was found for role of immunosenescence in frailty in the…”
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