Search Results - "Coll i Coll, M. Josep"

3FC1.2 Niemann-Pick disease type C when to give and discontinue treatment with substrate inhibitor therapy by Marfa, M. Pineda, del Socorro Pérez Poyato, M., del MarO' Callaghan Gordo, M., Vidal, J. Macías, Coll i Coll, M. Josep, Aracil, A.

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Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice by Lim, Ryan G, Salazar, Lisa L, Wilton, Daniel K, King, Alvin R, Stocksdale, Jennifer T, Sharifabad, Delaram, Lau, Alice L, Stevens, Beth, Reidling, Jack C, Winokur, Sara T, Casale, Malcolm S, Thompson, Leslie M, Pardo, Mónica, Díaz-Barriga, A Gerardo García, Straccia, Marco, Sanders, Phil, Alberch, Jordi, Canals, Josep M, Kaye, Julia A, Dunlap, Mariah, Jo, Lisa, May, Hanna, Mount, Elliot, Anderson-Bergman, Cliff, Haston, Kelly, Finkbeiner, Steven, Kedaigle, Amanda J, Gipson, Theresa A, Yildirim, Ferah, Ng, Christopher W, Milani, Pamela, Housman, David E, Fraenkel, Ernest, Allen, Nicholas D, Kemp, Paul J, Atwal, Ranjit Singh, Biagioli, Marta, Gusella, James F, MacDonald, Marcy E, Akimov, Sergey S, Arbez, Nicolas, Stewart, Jacqueline, Ross, Christopher A, Mattis, Virginia B, Tom, Colton M, Ornelas, Loren, Sahabian, Anais, Lenaeus, Lindsay, Mandefro, Berhan, Sareen, Dhruv, Svendsen, Clive N

“…The Huntington's disease (HD) induced pluripotent stem cell (iPSC) consortium describe the combined use of differentiated patient-derived iPSCs and systems…”
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Disease‐specific phenotypes in dopamine neurons from human iPS‐based models of genetic and sporadic Parkinson's disease by Sánchez‐Danés, Adriana, Richaud‐Patin, Yvonne, Carballo‐Carbajal, Iria, Jiménez‐Delgado, Senda, Caig, Carles, Mora, Sergio, Di Guglielmo, Claudia, Ezquerra, Mario, Patel, Bindiben, Giralt, Albert, Canals, Josep M., Memo, Maurizio, Alberch, Jordi, López‐Barneo, José, Vila, Miquel, Cuervo, Ana Maria, Tolosa, Eduard, Consiglio, Antonella, Raya, Angel

“…Induced pluripotent stem cells (iPSC) offer an unprecedented opportunity to model human disease in relevant cell types, but it is unclear whether they could…”
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Development of a Novel Anti-CD19 Chimeric Antigen Receptor: A Paradigm for an Affordable CAR T Cell Production at Academic Institutions by Castella, Maria, Boronat, Anna, Martín-Ibáñez, Raquel, Rodríguez, Vanina, Suñé, Guillermo, Caballero, Miguel, Marzal, Berta, Pérez-Amill, Lorena, Martín-Antonio, Beatriz, Castaño, Julio, Bueno, Clara, Balagué, Olga, González-Navarro, Europa Azucena, Serra-Pages, Carles, Engel, Pablo, Vilella, Ramon, Benitez-Ribas, Daniel, Ortiz-Maldonado, Valentín, Cid, Joan, Tabera, Jaime, Canals, Josep M, Lozano, Miquel, Baumann, Tycho, Vilarrodona, Anna, Trias, Esteve, Campo, Elías, Menendez, Pablo, Urbano-Ispizua, Álvaro, Yagüe, Jordi, Pérez-Galán, Patricia, Rives, Susana, Delgado, Julio, Juan, Manel

“…Genetically modifying autologous T cells to express an anti-CD19 chimeric antigen receptor (CAR) has shown impressive response rates for the treatment of CD19+…”
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Mutant huntingtin impairs post-Golgi trafficking to lysosomes by delocalizing optineurin/Rab8 complex from the Golgi apparatus by del Toro, Daniel, Alberch, Jordi, Lázaro-Diéguez, Francisco, Martín-Ibáñez, Raquel, Xifró, Xavier, Egea, Gustavo, Canals, Josep M

“…Huntingtin regulates post-Golgi trafficking of secreted proteins. Here, we studied the mechanism by which mutant huntingtin impairs this process…”
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Myeloid C/EBPβ deficiency reshapes microglial gene expression and is protective in experimental autoimmune encephalomyelitis by Pulido-Salgado, Marta, Vidal-Taboada, Jose M, Garcia Diaz-Barriga, Gerardo, Serratosa, Joan, Valente, Tony, Castillo, Paola, Matalonga, Jonathan, Straccia, Marco, Canals, Josep M, Valledor, Annabel, Solà, Carme, Saura, Josep

“…CCAAT/enhancer binding protein β (C/EBPβ) is a transcription factor that regulates the expression of important pro-inflammatory genes in microglia. Mice…”
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Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons by Martín-Ibáñez, Raquel, Pardo, Mónica, Giralt, Albert, Miguez, Andrés, Guardia, Inés, Marion-Poll, Lucile, Herranz, Cristina, Esgleas, Miriam, Garcia-Díaz Barriga, Gerardo, Edel, Michael J, Vicario-Abejón, Carlos, Alberch, Jordi, Girault, Jean-Antoine, Chan, Susan, Kastner, Philippe, Canals, Josep M

“…Here, we unravel the mechanism of action of the Ikaros family zinc finger protein Helios (He) during the development of striatal medium spiny neurons (MSNs)…”
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Cystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase by Borrell-Pagès, Maria, Canals, Josep M, Cordelières, Fabrice P, Parker, J Alex, Pineda, José R, Grange, Ghislaine, Bryson, Elzbieta A, Guillermier, Martine, Hirsch, Etienne, Hantraye, Philippe, Cheetham, Michael E, Néri, Christian, Alberch, Jordi, Brouillet, Emmanuel, Saudou, Frédéric, Humbert, Sandrine

“…There is no treatment for the neurodegenerative disorder Huntington disease (HD). Cystamine is a candidate drug; however, the mechanisms by which it operates…”
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Myeloid C/EBPβ deficiency reshapes microglial gene expression and is protective in experimental autoimmune encephalomyelitis by Pulido Salgado, Marta, Vidal Taboada, José Manuel, Garcia Diaz-Barriga, Gerardo, Serratosa i Serdà, Joan, Valente, Tony, Castillo, Paola, Matalonga, Jonathan, Straccia, Marco, Canals i Coll, Josep M, Valledor Fernández, Annabel, Solà i Subirana, Carme, Saura Martí, Josep

“…Background CCAAT/enhancer binding protein β (C/EBPβ) is a transcription factor that regulates the expression of important pro-inflammatory genes in microglia…”
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Mutant huntingtin Impairs the Post-Golgi Trafficking of Brain-Derived Neurotrophic Factor But Not Its Val66Met Polymorphism by del Toro, Daniel, Canals, Josep M, Gines, Silvia, Kojima, Masami, Egea, Gustavo, Alberch, Jordi

“…Brain-derived neurotrophic factor (BDNF) polymorphism is associated with the pathophysiology of several neurodegenerative disorders, including Huntington's…”
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Fast and Efficient Neural Conversion of Human Hematopoietic Cells by Castaño, Julio, Menendez, Pablo, Bruzos-Cidon, Cristina, Straccia, Marco, Sousa, Amaia, Zabaleta, Lorea, Vazquez, Nerea, Zubiarrain, Amaia, Sonntag, Kai-Christian, Ugedo, Luisa, Carvajal-Vergara, Xonia, Canals, Josep Maria, Torrecilla, Maria, Sanchez-Pernaute, Rosario, Giorgetti, Alessandra

“…Neurons obtained directly from human somatic cells hold great promise for disease modeling and drug screening. Available protocols rely on overexpression of…”
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Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease by Sánchez-Danés, Adriana, Richaud-Patin, Yvonne, Carballo-Carbajal, Iria, Jiménez-Delgado, Senda, Caig, Carles, Mora, Sergio, Di Guglielmo, Claudia, Ezquerra, Mario, Patel, Bindiben, Giralt Torroella, Albert, Canals i Coll, Josep M, Memo, Maurizio, Alberch i Vié, Jordi, López-Barneo, José, Vila Farré, Miquel, Cuervo, Ana Maria, Tolosa, Eduardo, Consiglio, Antonella, Raya Chamorro, Ángel

“…Induced pluripotent stem cells (iPSC) offer an unprecedented opportunity to model human disease in relevant cell types, but it is unclear whether they could…”
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Nolz1 promotes striatal neurogenesis through the regulation of retinoic acid signaling by Urbán, Noelia, Martín-Ibáñez, Raquel, Herranz, Cristina, Esgleas, Miriam, Crespo, Empar, Pardo, Monica, Crespo-Enríquez, Ivan, Méndez-Gómez, Héctor R, Waclaw, Ronald, Chatzi, Christina, Alvarez, Susana, Alvarez, Rosana, Duester, Gregg, Campbell, Kenneth, de Lera, Angel R, Vicario-Abejón, Carlos, Martinez, Salvador, Alberch, Jordi, Canals, Josep M

“…Nolz1 is a zinc finger transcription factor whose expression is enriched in the lateral ganglionic eminence (LGE), although its function is still unknown. Here…”
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Increased opioid dependence in a mouse model of panic disorder by Gallego, Xavier, Murtra, Patricia, Zamalloa, Teresa, Canals, Josep Maria, Pineda, Joseba, Amador-Arjona, Alejandro, Maldonado, Rafael, Dierssen, Mara

“…Panic disorder is a highly prevalent neuropsychiatric disorder that shows co-occurrence with substance abuse. Here, we demonstrate that TrkC, the high-affinity…”
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Nolz1 promotes striatal neurogenesis through the regulation of retinoic acid signaling by Urbán Avellaneda, Noelia, Martín Ibáñez, Raquel, Herranz, Cristina, Esgleas, Miriam, Crespo, Empar, Pardo Muñoz, Mònica, Crespo-Enríquez, Ivan, Méndez-Gómez, Héctor R, Waclaw, Ronald, Chatzi, Christina, Álvarez, Susana, Álvarez, Rosana, Duester, Gregg, Campbell, Kenneth, Lera, Ángel R. de, Vicario Abejón, Carlos, Martínez, Salvador, Alberch i Vié, Jordi, Canals i Coll, Josep M

“…Background: Nolz1 is a zinc finger transcription factor whose expression is enriched in the lateral ganglionic eminence (LGE), although its function is still…”
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