Search Results - "Colin, Didier J."

Gut Microbiota Orchestrates Energy Homeostasis during Cold by Chevalier, Claire, Stojanović, Ozren, Colin, Didier J., Suarez-Zamorano, Nicolas, Tarallo, Valentina, Veyrat-Durebex, Christelle, Rigo, Dorothée, Fabbiano, Salvatore, Stevanović, Ana, Hagemann, Stefanie, Montet, Xavier, Seimbille, Yann, Zamboni, Nicola, Hapfelmeier, Siegfried, Trajkovski, Mirko

“…Microbial functions in the host physiology are a result of the microbiota-host co-evolution. We show that cold exposure leads to marked shift of the microbiota…”
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Caloric Restriction Leads to Browning of White Adipose Tissue through Type 2 Immune Signaling by Fabbiano, Salvatore, Suárez-Zamorano, Nicolas, Rigo, Dorothée, Veyrat-Durebex, Christelle, Stevanovic Dokic, Ana, Colin, Didier J., Trajkovski, Mirko

“…Caloric restriction (CR) extends lifespan from yeast to mammals, delays onset of age-associated diseases, and improves metabolic health. We show that CR…”
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Microbiota depletion promotes browning of white adipose tissue and reduces obesity by Suárez-Zamorano, Nicolas, Fabbiano, Salvatore, Chevalier, Claire, Stojanović, Ozren, Colin, Didier J, Stevanović, Ana, Veyrat-Durebex, Christelle, Tarallo, Valentina, Rigo, Dorothée, Germain, Stéphane, Ilievska, Miroslava, Montet, Xavier, Seimbille, Yann, Hapfelmeier, Siegfried, Trajkovski, Mirko

“…Browning of white adipose tissue is induced by depletion of the microbiota, improving metabolic disease and reducing obesity. Brown adipose tissue (BAT)…”
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Ectopic UCP1 Overexpression in White Adipose Tissue Improves Insulin Sensitivity in Lou/C Rats, a Model of Obesity Resistance by Poher, Anne-Laure, Veyrat-Durebex, Christelle, Altirriba, Jordi, Montet, Xavier, Colin, Didier J, Caillon, Aurélie, Lyautey, Jacqueline, Rohner-Jeanrenaud, Françoise

“…Brown adipose tissue (BAT), characterized by the presence of uncoupling protein 1 (UCP1), has been described as metabolically active in humans. Lou/C rats,…”
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P-Glycoprotein 1 Affects Chemoactivities of Resveratrol against Human Colorectal Cancer Cells by Aires, Virginie, Colin, Didier J, Doreau, Agnès, Di Pietro, Attilio, Heydel, Jean-Marie, Artur, Yves, Latruffe, Norbert, Delmas, Dominique

“…Resveratrol has been proposed to prevent tumor growth and the different steps of carcinogenesis; nevertheless, these biological effects are sometimes…”
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The impact of short-term machine perfusion on the risk of cancer recurrence after rat liver transplantation with donors after circulatory death by Oldani, Graziano, Peloso, Andrea, Slits, Florence, Gex, Quentin, Delaune, Vaihere, Orci, Lorenzo A, van de Looij, Yohan, Colin, Didier J, Germain, Stéphane, de Vito, Claudio, Rubbia-Brandt, Laura, Lacotte, Stéphanie, Toso, Christian

“…Hypothermic and normothermic ex vivo liver perfusions promote organ recovery after donation after circulatory death (DCD). We tested whether these perfusions…”
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Experimental Model of Human Malignant Mesothelioma in Athymic Mice by Colin, Didier J, Cottet-Dumoulin, David, Faivre, Anna, Germain, Stéphane, Triponez, Frédéric, Serre-Beinier, Véronique

“…Malignant pleural mesothelioma (MPM) is a thoracic aggressive cancer caused by asbestos exposure, which is difficult to diagnose and treat. Here, we…”
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Cellular responses to a prolonged delay in mitosis are determined by a DNA damage response controlled by Bcl-2 family proteins by Colin, Didier J., Hain, Karolina O., Allan, Lindsey A., Clarke, Paul R.

“…Anti-cancer drugs that disrupt mitosis inhibit cell proliferation and induce apoptosis, although the mechanisms of these responses are poorly understood. Here,…”
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Time-of-flight and black-blood MRI to study intracranial arteries in rats by Cayron, Anne F., Bejuy, Olivia, Vargas, Maria Isabel, Colin, Didier J., Aoki, Tomohiro, Lövblad, Karl-Olof, Bijlenga, Philippe, Kwak, Brenda R., Allémann, Eric, Morel, Sandrine

“…Intracranial aneurysms (IAs) are usually incidentally discovered by magnetic resonance imaging (MRI). Once discovered, the risk associated with their treatment…”
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Short-term 3D culture systems of various complexity for treatment optimization of colorectal carcinoma by Zoetemelk, Marloes, Rausch, Magdalena, Colin, Didier J., Dormond, Olivier, Nowak-Sliwinska, Patrycja

“…Three-dimensional (3D) cultures have the potential to increase the predictive value of pre-clinical drug research and bridge the gap towards anticipating…”
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Revealing the complexity of ultra-soft hydrogel re-swelling inside the brain by Shur, Michael, Akouissi, Outman, Rizzo, Olivier, Colin, Didier J., Kolinski, John M., Lacour, Stéphanie P.

“…The brain is an ultra-soft viscoelastic matrix. Sub-kPa hydrogels match the brain's mechanical properties but are challenging to manipulate in an implantable…”
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Preclinical validations of [18F]FPyPEGCBT-c(RGDfK): a 18F-labelled RGD peptide prepared by ligation of 2-cyanobenzothiazole and 1,2-aminothiol to image angiogenesis by Colin, Didier J., Inkster, James A. H., Germain, Stéphane, Seimbille, Yann

“…Background α V β 3 , α V β 5 and α 5 β 1 integrins are known to be involved in carcinogenesis and are overexpressed in many types of tumours compared to…”
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Prolonged mitotic arrest induces a caspase-dependent DNA damage response at telomeres that determines cell survival by Hain, Karolina O., Colin, Didier J., Rastogi, Shubhra, Allan, Lindsey A., Clarke, Paul R.

“…A delay in the completion of metaphase induces a stress response that inhibits further cell proliferation or induces apoptosis. This response is thought to…”
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Does non-activated platelet-rich plasma (PRP) enhance fat graft outcome? An assessment with 3D CT-scan in mice by Atashi, Fatemeh, André-Lévigne, Dominik, Colin, Didier J., Germain, Stéphane, Pittet-Cuénod, Brigitte, Modarressi, Ali

“…The adjunction of autologous platelet-rich plasma (PRP) is emerging as a promising approach to enhance the long-term survival of fat grafting, but there are…”
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Importance of lipid microdomains, rafts, in absorption, delivery, and biological effects of resveratrol by Delmas, Dominique, Aires, Virginie, Colin, Didier J., Limagne, Emeric, Scagliarini, Alessandra, Cotte, Alexia K., Ghiringhelli, François

“…The preventive effects of the phytoalexin trans‐resveratrol toward cancer have been largely described at the cellular and molecular levels in both in vivo and…”
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A novel 2-cyanobenzothiazole-based (18)F prosthetic group for conjugation to 1,2-aminothiol-bearing targeting vectors by Inkster, James A H, Colin, Didier J, Seimbille, Yann

“…In a bid to find an efficient means to radiolabel biomolecules under mild conditions for PET imaging, a bifunctional (18)F prosthetic molecule has been…”
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Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice by Colin, Didier J, Bejuy, Olivia, Germain, Stéphane, Triponez, Frédéric, Serre-Beinier, Véronique

“…Malignant pleural mesothelioma (MPM) is a rare and aggressive tumor arising in the mesothelium that covers the lungs, the heart, and the thoracic cavity. MPM…”
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Tristetraprolin Promotes Hepatic Inflammation and Tumor Initiation but Restrains Cancer Progression to Malignancy by Dolicka, Dobrochna, Sobolewski, Cyril, Gjorgjieva, Monika, Correia de Sousa, Marta, Berthou, Flavien, De Vito, Claudio, Colin, Didier J., Bejuy, Olivia, Fournier, Margot, Maeder, Christine, Blackshear, Perry J., Rubbia-Brandt, Laura, Foti, Michelangelo

“…Tristetraprolin (TTP) is a key post-transcriptional regulator of inflammatory and oncogenic transcripts. Accordingly, TTP was reported to act as a tumor…”
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Role of MIF/CD74 signaling pathway in the development of pleural mesothelioma by D'Amato-Brito, Cintia, Cipriano, Davide, Colin, Didier J, Germain, Stéphane, Seimbille, Yann, Robert, John H, Triponez, Frédéric, Serre-Beinier, Véronique

“…Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine implicated in acute and chronic inflammatory diseases. MIF is overexpressed in…”
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[11C]acetate and PET/CT assessment of muscle activation in rat studies by Trombella, Sara, García, David, Colin, Didier J., Germain, Stéphane, Seimbille, Yann, Ratib, Osman

“…Purpose The purpose of the present study is to apply kinetic analysis to investigate exercise-related changes in the metabolism of the skeletal muscle of the…”
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