Search Results - "Coley, H."

The context and potential of epigenetics in oncology by Lopez, J, Percharde, M, Coley, H M, Webb, A, Crook, T

“…Cancer has long been known to be a disease caused by alterations in the genetic blueprint of cells. In the past decade it has become evident that epigenetic…”
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Paclitaxel resistance is associated with switch from apoptotic to autophagic cell death in MCF-7 breast cancer cells by Ajabnoor, G M A, Crook, T, Coley, H M

“…Taxanes remain first line chemotherapy in management of metastatic breast cancer and have a key role in epithelial ovarian cancer, with increasingly common use…”
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Epigenetic status of argininosuccinate synthetase and argininosuccinate lyase modulates autophagy and cell death in glioblastoma by Syed, N, Langer, J, Janczar, K, Singh, P, Lo Nigro, C, Lattanzio, L, Coley, H M, Hatzimichael, E, Bomalaski, J, Szlosarek, P, Awad, M, O'Neil, K, Roncaroli, F, Crook, T

“…Arginine deprivation, either by nutritional starvation or exposure to ADI-PEG20, induces adaptive transcriptional upregulation of ASS1 and ASL in glioblastoma…”
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Comparative analyses between younger and older patients with pancreatic adenocarcinoma: differences in clinicopathological features, treatment patterns, and outcomes by Salem, M., Kadakia, K., Trufan, S., Hwang, J., Nazemzadeh, R., Jagosky, M., Worrilow, W., Coley, H., Al Hallak, M., Gower, N., Philip, P., O’Reilly, E.

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Design of double-walled carbon nanotubes for biomedical applications by Neves, V, Heister, E, Costa, S, Tîlmaciu, C, Flahaut, E, Soula, B, Coley, H M, McFadden, J, Silva, S R P

“…Double-walled carbon nanotubes (DWNTs) prepared by catalytic chemical vapour deposition were functionalized in such a way that they were optimally designed as…”
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AFM imaging of functionalized carbon nanotubes on biological membranes by Lamprecht, C, Liashkovich, I, Neves, V, Danzberger, J, Heister, E, Rangl, M, Coley, H M, McFadden, J, Flahaut, E, Gruber, H J, Hinterdorfer, P, Kienberger, F, Ebner, A

“…Multifunctional carbon nanotubes are promising for biomedical applications as their nano-size, together with their physical stability, gives access into the…”
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521 Cell Cycle Regulation Changes in Drug-Resistant Cancers by Safuwan, N. Mohd, Crook, T, Coley, H

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Dielectrophoretic analysis of changes in cytoplasmic ion levels due to ion channel blocker action reveals underlying differences between drug-sensitive and multidrug-resistant leukaemic cells by Duncan, L, Shelmerdine, H, Hughes, M P, Coley, H M, Hübner, Y, Labeed, F H

“…Dielectrophoresis (DEP)--the motion of particles in non-uniform AC fields-has been used in the investigation of cell electrophysiology. The technique offers…”
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The cyclin-dependent kinase inhibitor p57 Kip2 is epigenetically regulated in carboplatin resistance and results in collateral sensitivity to the CDK inhibitor seliciclib in ovarian cancer by COLEY, H. M, SAFUWAN, N. A. M, CHIVERS, P, PAPACHARALBOUS, E, GIANNOPOULOS, T, BUTLER-MANUEL, S, MADHURI, K, LOVELL, D. P, CROOK, T

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The cyclin-dependent kinase inhibitor p57(Kip2) is epigenetically regulated in carboplatin resistance and results in collateral sensitivity to the CDK inhibitor seliciclib in ovarian cancer by Coley, H M, Safuwan, N A M, Chivers, P, Papacharalbous, E, Giannopoulos, T, Butler-Manuel, S, Madhuri, K, Lovell, D P, Crook, T

“…Carboplatin remains a first-line agent in the management of epithelial ovarian cancer (EOC). Unfortunately, platinum-resistant disease ultimately occurs in…”
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Microbeam PIXE analysis of platinum resistant and sensitive ovarian cancer cells by Jeynes, J.C.G., Bailey, M.J., Coley, H., Kirkby, K.J., Jeynes, C.

“…Microbeam PIXE was used to analyse platinum in single ovarian cancer cells. Carboplatin sensitive and resistant cells were grown as a monolayer on…”
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The risk of regional lymph node metastases in patients with melanoma less than 1.0 mm thick: recommendations for sentinel lymph node biopsy by Zapas, John L, Coley, H Christopher, Beam, Sandra L, Brown, Sally D, Jablonski, Kathleen A, Elias, E George

“…Lymphatic mapping and sentinel lymph node biopsy can upstage patients with intermediate thickness (1.0 to 4.0 mm) melanoma. Currently, there are no strict…”
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COX-2 Inhibition: A Possible Role in the Management of Prostate Cancer? by Sooriakumaran, P., Langley, S.E.M., Laing, R.W., Coley, H.M.

“…There is mounting evidence to support a role for cyclooxygenase-2 (COX-2) inhibitors (coxibs) in the management of prostate cancer. This review considers the…”
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Examination by laser scanning confocal fluorescence imaging microscopy of the subcellular localisation of anthracyclines in parent and multidrug resistant cell lines by COLEY, H. M, AMOS, W. B, TWENTYMAN, P. R, WORKMAN, P

“…This study highlights the usefulness of laser scanning confocal microscopy in the examination of subcellular disposition of anthracyclines in tumour cell…”
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CHANGES IN SOIL POLLEN ASSEMBLAGES ON FOOTWEAR WORN AT DIFFERENT SITES by RIDING, JAMES B, RAWLINS, BARRY G, COLEY, KIRSTIN H

“…The application of palynology to forensic investigations relies on the similarity of pollen assemblages from forensic items, such as footwear, with control…”
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Incidence of P-glycoprotein overexpression and multidrug resistance (MDR) reversal in adult soft tissue sarcoma by Coley, H.M, Verrill, M.W, Gregson, S.E, Odell, D.E, Fisher, C, Judson, I.R

“…Multidrug resistance (MDR) is a widespread problem in the treatment of neoplastic diseases and may limit the effectiveness of treatment of adult soft tissue…”
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A Gene Expression Profiling Approach Assessing Celecoxib in a Randomized Controlled Trial in Prostate Cancer by Sooriakumaran, P, Macanas-Pirard, P, Bucca, G, Henderson, A, Langley, S E M, Laing, R W, Smith, C P, Laing, E E, Coley, H M

“…Background: We performed a pilot study, looking at the COX-2 inhibitor celecoxib, on newly diagnosed prostate cancer patients in the neo-adjuvant setting using…”
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The cyclin-dependent kinase inhibitor p57Kip2 is epigenetically regulated in carboplatin resistance and results in collateral sensitivity to the CDK inhibitor seliciclib in ovarian cancer by Coley, H M, Safuwan, N A M, Chivers, P, Papacharalbous, E, Giannopoulos, T, Butler-Manuel, S, Madhuri, K, Lovell, D P, Crook, T

“…Background: Carboplatin remains a first-line agent in the management of epithelial ovarian cancer (EOC). Unfortunately, platinum-resistant disease ultimately…”
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Copper bis(diphosphine) complexes: radiopharmaceuticals for the detection of multi-drug resistance in tumours by PET by Lewis, J S, Dearling, J L, Sosabowski, J K, Zweit, J, Carnochan, P, Kelland, L R, Coley, H M, Blower, P J

“…Experience with imaging of the multi-drug resistance (MDR) phenotype in tumours using technetium-99m sestamibi, a substrate of the P-glycoprotein (Pgp)…”
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Retention of activity by selected anthracyclines in a multidrug resistant human large cell lung carcinoma line without P-glycoprotein hyperexpression by COLEY, H. M, WORKMAN, P, TWENTYMAN, P. R

“…A subline (COR-L23/R) of the human large cell lung line [corrected] COR-L23, derived by in vivo exposure to doxorubicin, exhibits an unusual multidrug…”
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