Search Results - "Coleman, Rachel A"

Methods to Discover and Evaluate Proteasome Small Molecule Stimulators by Coleman, Rachel A, Trader, Darci J

“…Protein accumulation has been identified as a characteristic of many degenerative conditions, such as neurodegenerative diseases and aging. In most cases,…”
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Development and Application of a Sensitive Peptide Reporter to Discover 20S Proteasome Stimulators by Coleman, Rachel A, Trader, Darci J

“…To attenuate an overabundance of cellular protein, it has been hypothesized that the 20S core particle (20S CP) of the proteasome can be chemically stimulated…”
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Fluorescent Probes with Unnatural Amino Acids to Monitor Proteasome Activity in Real-Time by Zerfas, Breanna L, Coleman, Rachel A, Salazar-Chaparro, Andres F, Macatangay, Nathaniel J, Trader, Darci J

“…The proteasome is an essential protein complex that, when dysregulated, can result in various diseases in eukaryotic cells. As such, understanding the…”
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Analysis of chain length, substitution patterns, and unsaturation of AM-404 derivatives as 20S proteasome stimulators by Coleman, Rachel A., Muli, Christine S., Zhao, Yizhou, Bhardwaj, Atul, Newhouse, Timothy R., Trader, Darci J.

“…[Display omitted] Proteasome-mediated degradation of proteins is a vital cellular process and is performed by the ubiquitin-dependent proteasome system (UPS)…”
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Measuring Meaning: Searching for and Making Sense of Spousal Loss in Late-Life by Coleman, Rachel A., Neimeyer, Robert A.

“…Despite much recent theorizing, evidence regarding the temporal relationship of sense-making to adjustment following bereavement remains relatively sparse…”
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The Integration of Stressful Life Experiences Scale (ISLES): Development and Initial Validation of a New Measure by Holland, Jason M, Currier, Joseph M, Coleman, Rachel A, Neimeyer, Robert A

“…Making meaning out of life stressors has been proposed as a crucial mechanism by which individuals adjust to these experiences. However, an easy-to-use,…”
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Protein degradation profile reveals dynamic nature of 20S proteasome small molecule stimulation by Coleman, Rachel A, Mohallem, Rodrigo, Aryal, Uma K, Trader, Darci J

“…Small molecules have been discovered to stimulate the 20S core particle (CP) of the proteasome to degrade proteins. However, the impact a 20S CP stimulator can…”
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All About the Core: A Therapeutic Strategy to Prevent Protein Accumulation with Proteasome Core Particle Stimulators by Coleman, Rachel A, Trader, Darci J

“…The proteasome is an essential enzyme complex in cells whose main responsibility is to degrade proteins. Proteins can be degraded through either a…”
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Assessment of Subjective Client Agency in Psychotherapy: A Review by Coleman, Rachel A., Neimeyer, Robert A.

“…Theoretical accounts of psychotherapy, especially of a constructivist or humanistic sort, often assert the importance of the client's active efforts in "making…”
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The Resolution of Anger in Psychotherapy: A Task Analysis by Kannan, Divya, Henretty, Jennifer R, Piazza-Bonin, Elizabeth, Levitt, Heidi M, Coleman, Rachel A, Bickerest-Townsend, Manda, Mathews, Susan S

“…Anger often is conceptualized as a disruptive emotional force, but it may be seen as an adaptive internal signal that cues self-protective action. In this…”
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Increasing subjective client agency for psychotherapy at a Veterans Administration hospital: A process-outcome study by Coleman, Rachel A

“…Subjective client agency, defined as client expectations for actively influencing therapy process and outcome, is hypothesized to contribute to psychotherapy…”
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