Search Results - "Coleman, RL"
-
1
Effects of acarbose on cardiovascular and diabetes outcomes in patients with coronary heart disease and impaired glucose tolerance (ACE): a randomised, double-blind, placebo-controlled trial
Published in The lancet. Diabetes & endocrinology (01-11-2017)“…The effect of the α-glucosidase inhibitor acarbose on cardiovascular outcomes in patients with coronary heart disease and impaired glucose tolerance is…”
Get full text
Journal Article -
2
Impact of Acarbose on Incident Diabetes and Regression to Normoglycemia in People With Coronary Heart Disease and Impaired Glucose Tolerance: Insights From the ACE Trial
Published in Diabetes care (01-09-2020)“…We examined the impact of acarbose, an α-glucosidase inhibitor, on incident diabetes and regression to normoglycemia in 6,522 Acarbose Cardiovascular…”
Get full text
Journal Article -
3
Predicting heart failure events in patients with coronary heart disease and impaired glucose tolerance: Insights from the Acarbose Cardiovascular Evaluation (ACE) trial
Published in Diabetes research and clinical practice (01-12-2020)“…•Higher age and plasma creatinine, lower haemoglobin, and HF, MI or AF predicted hHF.•Higher age and creatinine values predicted case fatality.•Acarbose did…”
Get full text
Journal Article -
4
Comparison of medical resources and costs among patients with coronary heart disease and impaired glucose tolerance in the Acarbose Cardiovascular Evaluation trial
Published in Journal of diabetes (01-02-2024)“…Background The Acarbose Cardiovascular Evaluation (ACE) trial (ISRCTN91899513) evaluated the alpha‐glucosidase inhibitor acarbose, compared with placebo, in…”
Get full text
Journal Article -
5
Targeted PI3K/AKT/mTOR therapy for metastatic carcinomas of the cervix: A phase I clinical experience
Published in Oncotarget (30-11-2014)“…Activated PI3K/AKT/mTOR pathway frequently occurs in metastatic or recurrent cervical carcinomas. However, the clinical benefits of matched therapy, a…”
Get full text
Journal Article -
6
A phase II evaluation of aflibercept in the treatment of recurrent or persistent endometrial cancer: A Gynecologic Oncology Group study
Published in Gynecologic oncology (01-12-2012)“…Abstract Objectives Aflibercept targets vascular endothelial growth factor and placental growth factor. We evaluated activity and toxicity of aflibercept in…”
Get full text
Journal Article -
7
Baseline characteristics and temporal differences in Acarbose Cardiovascular Evaluation (ACE) trial participants
Published in The American heart journal (01-05-2018)“…The ACE trial is examining whether acarbose, an insulin-sparing postprandial glucose-lowering agent, can reduce cardiovascular (CV) events in patients who have…”
Get full text
Journal Article -
8
Risk Factors for Myocardial Infarction Case Fatality and Stroke Case Fatality in Type 2 Diabetes
Published in Diabetes care (01-01-2004)“…Risk Factors for Myocardial Infarction Case Fatality and Stroke Case Fatality in Type 2 Diabetes UKPDS 66 Richard J. Stevens , PHD , Ruth L. Coleman , BSC ,…”
Get full text
Journal Article -
9
Critical evaluation of secondary cytoreduction in recurrent ovarian cancer
Published in Gynecologic oncology (01-11-2004)“…The optimal strategy for salvage therapy in patients who suffer from ovarian cancer recurrence after a disease-free interval is not established. The objective…”
Get full text
Journal Article -
10
-
11
Risk factors for heart failure in the ACE trial population
Published in DIABETOLOGIA (2019)Get full text
Conference Proceeding -
12
Feasibility of monitoring response to the PARP inhibitor rucaparib with targeted deep sequencing of circulating tumor DNA (ctDNA) in women with high grade ovarian carcinoma on the ARIEL2 trial
Published in European journal of cancer (1990) (01-12-2016)“…Background: TP53 mutations are present in >97% cases of high-grade serous ovarian cancer (HGSOC). Detection of TP53 mutations in ctDNA extracted from plasma…”
Get full text
Journal Article -
13
Secondary mutations in RAD51C and RAD51D are associated with acquired resistance to the PARP inhibitor rucaparib in patients with high-grade ovarian cancer
Published in European journal of cancer (1990) (01-12-2016)“…Background: High-grade ovarian carcinomas (HGOC) with mutated BRCA1, BRCA2, or other core homologous recombination repair (HRR) genes are sensitive to…”
Get full text
Journal Article -
14
Intraoperative Lymphatic Mapping and Sentinel Node Identification with Blue Dye in Patients with Vulvar Cancer
Published in Gynecologic oncology (01-11-2001)“…Objective. To determine the effectiveness of intraoperative lymphatic with blue dye alone as a means of localizing sentinel nodes in patients with vulvar…”
Get full text
Journal Article -
15
Phase I/II Trial of the Pharmacokinetics, Safety, and Antiretroviral Activity of Tenofovir Disoproxil Fumarate in Human Immunodeficiency Virus-Infected Adults
Published in Antimicrobial Agents and Chemotherapy (01-10-2001)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text
Journal Article -
16
Phase II trial of imatinib mesylate in patients with recurrent platinum- and taxane-resistant epithelial ovarian and primary peritoneal cancers
Published in Gynecologic oncology (01-04-2006)“…To evaluate the efficacy and tolerability of imatinib mesylate (Gleevec; Novartis Pharmaceuticals, Basel, Switzerland) in patients with recurrent ovarian and…”
Get full text
Journal Article -
17
Saline, mannitol, and furosemide hydration in acute cisplatin nephrotoxicity: a randomized trial
Published in Cancer chemotherapy and pharmacology (01-07-2003)“…To determine which hydration (saline, saline + mannitol, or saline + furosemide) is associated with least cisplatin nephrotoxicity. We randomized 49 women who…”
Get full text
Journal Article -
18
Effects of a laboratory-based skills curriculum on laparoscopic proficiency: A randomized trial
Published in American journal of obstetrics and gynecology (01-04-2002)“…Objective: The purpose of this study was to determine the effect and validity of an intensive laboratory-based laparoscopic skills training curriculum on…”
Get full text
Journal Article -
19
Intraperitoneal carboplatin-based chemotherapy for epithelial ovarian cancer
Published in Gynecologic oncology (01-04-2005)“…Intraperitoneal (IP) chemotherapy is an attractive approach to the treatment of ovarian cancer because the disease remains confined to the peritoneal cavity…”
Get full text
Journal Article -
20
Non-HDL Cholesterol Is Less Informative Than the Total-to-HDL Cholesterol Ratio in Predicting Cardiovascular Risk in Type 2 Diabetes
Published in Diabetes care (01-07-2005)“…Holman et al evaluate whether non-high density lipoprotein (HDL) cholesterol is less informative than the total-to-HDL cholesterol ratio in predicting…”
Get full text
Journal Article