Search Results - "Coleman, PJ"

Incidence of Hepatitis B Virus Infection in the United States, 1976–1994: Estimates from the National Health and Nutrition Examination Surveys by Coleman, Patrick J., McQuillan, Geraldine M., Moyer, Linda A., Lambert, Stephen B., Margolis, Harold S.

“…Precise estimates of the incidence of hepatitis B virus (HBV) infection are required to assess the impact of immunization and other prevention strategies in…”
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Harlequin syndrome following internal jugular vein catheterization in an adult under general anesthetic by Coleman, Patrick J, Goddard, Jane M

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0103 REM SLEEP IS INDUCED BY DUAL AND OREXIN 2 RECEPTOR ANTAGONISTS VIA MECHANISMS BEYOND ALPHA1-NORADRENERGIC SIGNALING by Gotter, AL, Stevens, J, Garson, SL, Fox, SV, Svetnik, V, 
Tannenbaum, PL, Forman, MS, Coleman, PJ, Herring, WJ, 
Renger, JJ, Winrow, CJ

“…Abstract Introduction: Orexin receptor (OX1R, OX2R) antagonism induces sleep architecture characterized by increases in both NREM and REM reminiscent of…”
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Kinesin spindle protein (KSP) inhibitors. Part 1: The discovery of 3,5-diaryl-4,5-dihydropyrazoles as potent and selective inhibitors of the mitotic kinesin KSP by Cox, Christopher D., Breslin, Michael J., Mariano, Brenda J., Coleman, Paul J., Buser, Carolyn A., Walsh, Eileen S., Hamilton, Kelly, Huber, Hans E., Kohl, Nancy E., Torrent, Maricel, Yan, Youwei, Kuo, Laurence C., Hartman, George D.

“…Optimization of high-throughput screening (HTS) hits resulted in the discovery of 3,5-diaryl-4,5-dihydropyrazoles as potent and selective inhibitors of KSP…”
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1,5-Asymmetric Induction in Boron-Mediated β-Alkoxy Methyl Ketone Aldol Addition Reactions by Evans, David A, Côté, Bernard, Coleman, Paul J, Connell, Brian T

“…This article presents studies that illustrate β-alkoxy methyl ketone-derived boron enolates undergo diastereoselective aldol addition to afford the 1,5-anti…”
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Prevalence of hepatitis B virus infection in the United States: the National Health and Nutrition Examination Surveys, 1976 through 1994 by McQuillan, G M, Coleman, P J, Kruszon-Moran, D, Moyer, L A, Lambert, S B, Margolis, H S

“…Data from 2 National Health and Nutrition Examination Surveys (NHANES), NHANES II (1976-1980) and NHANES III (1988-1994), were analyzed to examine trends in…”
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Enantioselective total synthesis of altohyrtin C (spongistatin 2) by Evans, David A., Trotter, B.Wesley, Coleman, Paul J., Côté, Bernard, Dias, Luiz Carlos, Rajapakse, Hemaka A., Tyler, Andrew N.

“…The first total synthesis of a spongipyran macrolide, altohyrtin C, is described. The convergent synthesis strategy relies on a regioselective…”
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Kinesin spindle protein (KSP) inhibitors. Part 2: The design, synthesis, and characterization of 2,4-diaryl-2,5-dihydropyrrole inhibitors of the mitotic kinesin KSP by Fraley, Mark E., Garbaccio, Robert M., Arrington, Kenneth L., Hoffman, William F., Tasber, Edward S., Coleman, Paul J., Buser, Carolyn A., Walsh, Eileen S., Hamilton, Kelly, Fernandes, Christine, Schaber, Michael D., Lobell, Robert B., Tao, Weikang, South, Victoria J., Yan, Youwei, Kuo, Lawrence C., Prueksaritanont, Thomayant, Shu, Cathy, Torrent, Maricel, Heimbrook, David C., Kohl, Nancy E., Huber, Hans E., Hartman, George D.

“…2,4-Diaryl-2,5-dihydropyrroles are reported as potent inhibitors of the mitotic kinesin KSP. The evolution of 2,4-diaryl-2,5-dihydropyrroles as inhibitors of…”
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Kinesin spindle protein (KSP) inhibitors. Part 4: Structure-based design of 5-alkylamino-3,5-diaryl-4,5-dihydropyrazoles as potent, water-soluble inhibitors of the mitotic kinesin KSP by COX, Christopher D, TORRENT, Maricel, LOBELL, Robert B, WEIKANG TAO, SOUTH, Vicki J, KOHL, Nancy E, YOUWEI YAN, KUO, Lawrence C, PRUEKSARITANONT, Thomayant, SLAUGHTER, Donald E, CHUNZE LI, MAHAN, Elizabeth, BRESLIN, Michael J, BING LU, HARTMAN, George D, MARIANO, Brenda J, WHITMAN, David B, COLEMAN, Paul J, BUSER, Carolyn A, WALSH, Eileen S, HAMILTON, Kelly, SCHABER, Michael D

“…Molecular modeling in combination with X-ray crystallographic information was employed to identify a region of the kinesin spindle protein (KSP) binding site…”
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1,5-Asymmetric Induction in Methyl Ketone Aldol Addition Reactions by Evans, David A, Coleman, Paul J, Côté, Bernard

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Evidence for a role of hyaluronan in the spacing of fibrils within collagen bundles in rabbit synovium by Coleman, Peter J

“…Synovial hydraulic resistance is vital for the retention of intra-articular fluid, and originates within the matrix of biopolymers in the intercellular gaps…”
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Size selectivity of hyaluronan molecular sieving by extracellular matrix in rabbit synovial joints by Sabaratnam, S., Arunan, V., Coleman, P. J., Mason, R. M., Levick, J. R.

“…In joint fluid the polymer hyaluronan (HA) confers viscous lubrication and greatly attenuates trans-synovial fluid loss (outflow buffering). Outflow buffering…”
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Enantioselective Synthesis of Altohyrtin C (Spongistatin 2): Synthesis of the AB- and CD-Spiroketal Subunits by Evans, David A., Coleman, Paul J., Dias, Luiz Carlos

“…The first total synthesis of a spongipyran macrolide, altohyrtin C (spongistatin 2; see picture below), has been realized. The spongipyrans derived from marine…”
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Glycosaminoglycan depletion greatly raises the hydraulic permeability of rabbit joint synovial lining by Scott, D, Coleman, P J, Mason, R M, Levick, J R

“…The hydraulic resistance of the synovial lining of a joint is important for retention of intraarticular lubricant. The resistance has been attributed to…”
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Observations on PAH, PCB, and PCDD/F Trends in U.K. Urban Air, 1991−1995 by Coleman, Peter J, Lee, Robert G. M, Alcock, Ruth E, Jones, Kevin C

“…Ambient air concentrations at London and Manchester are reported for PCBs, PAHs, and PCDD/Fs from 1991 to 1995. This data set suggests that urban PAH…”
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Enantioselective Synthesis of Altohyrtin C (Spongistatin 2): Fragment Assembly and Revision of the Spongistatin 2 Stereochemical Assignment by Evans, David A., Trotter, B. Wesley, Côté, Bernard, Coleman, Paul J., Dias, Luiz Carlos, Tyler, Andrew N.

“…The first total synthesis of a spongipyran macrolide, altohyrtin C (spongistatin 2; see picture below), has been realized. The spongipyrans derived from marine…”
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A Role for Hyaluronan in the Preservation of Interstitial Structure by COLEMAN, PETER J.

“…Hydraulic resistance of interstitium is of major importance in body fluid distribution. In the synovial lining it is vital for the retention of intra-articular…”
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Enantioselective Synthesis of Altohyrtin C (Spongistatin 2): Synthesis of the EF-Bis(pyran) Subunit by Evans, David A., Trotter, B. Wesley, Cǒté, Bernard, Coleman, Paul J.

“…The first total synthesis of a spongipyran macrolide, altohyrtin C (spongistatin 2; see picture below), has been realized. The spongipyrans derived from marine…”
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PCBs in U.K. Urban Air by Halsall, Crispin J, Lee, Robert G. M, Coleman, Peter J, Burnett, Victoria, Harding-Jones, Peter, Jones, Kevin C

“…Atmospheric PCB concentrations are modeled from data acquired by monitoring four UK urban centers every other week during a two-year period. The evidence…”
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Polycyclic Aromatic Hydrocarbons in U.K. Urban Air by Halsall, Crispin J, Coleman, Peter J, Davis, Brian J, Burnett, Victoria, Waterhouse, Keith S, Harding-Jones, Peter, Jones, Kevin C

“…Polycyclic aromatic hydrocarbon data for the first two years of a national urban air monitoring survey in the UK are presented. The results show that…”
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