Search Results - "Coleman, Haley A."

Unique, dual-indexed sequencing adapters with UMIs effectively eliminate index cross-talk and significantly improve sensitivity of massively parallel sequencing by MacConaill, Laura E, Burns, Robert T, Nag, Anwesha, Coleman, Haley A, Slevin, Michael K, Giorda, Kristina, Light, Madelyn, Lai, Kevin, Jarosz, Mirna, McNeill, Matthew S, Ducar, Matthew D, Meyerson, Matthew, Thorner, Aaron R

“…Sample index cross-talk can result in false positive calls when massively parallel sequencing (MPS) is used for sensitive applications such as low-frequency…”
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Neuropeptidergic signaling partitions arousal behaviors in zebrafish by Woods, Ian G, Schoppik, David, Shi, Veronica J, Zimmerman, Steven, Coleman, Haley A, Greenwood, Joel, Soucy, Edward R, Schier, Alexander F

“…Animals modulate their arousal state to ensure that their sensory responsiveness and locomotor activity match environmental demands. Neuropeptides can regulate…”
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Abstract 3644: Optimization of library construction for massively parallel sequencing using low-input, FFPE-derived DNA without additional PCR amplification by Thorner, Aaron R., Ziaugra, Liuda, Ducar, Matthew D., Lin, Ling, Laing, Angelica, Coleman, Haley A., McShane, Suzanne R., Clapp, Andrea, Paquette, Rachel R., Wollison, Bruce M., Hoeftberger, Johann, Patel, Neil A., Hunter, Samuel S., Manam, Monica D., MacConaill, Laura E., Hahn, William C., Meyerson, Matthew L., van Hummelen, Paul

“…Massively parallel sequencing (MPS) is increasingly used in the laboratory and clinic to identify genomic factors contributing to tumorigenesis, such as…”
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Genomic Heterogeneity as a Barrier to Precision Medicine in Gastroesophageal Adenocarcinoma by Pectasides, Eirini, Stachler, Matthew D, Derks, Sarah, Liu, Yang, Maron, Steven, Islam, Mirazul, Alpert, Lindsay, Kwak, Heewon, Kindler, Hedy, Polite, Blase, Sharma, Manish R, Allen, Kenisha, O'Day, Emily, Lomnicki, Samantha, Maranto, Melissa, Kanteti, Rajani, Fitzpatrick, Carrie, Weber, Christopher, Setia, Namrata, Xiao, Shu-Yuan, Hart, John, Nagy, Rebecca J, Kim, Kyoung-Mee, Choi, Min-Gew, Min, Byung-Hoon, Nason, Katie S, O'Keefe, Lea, Watanabe, Masayuki, Baba, Hideo, Lanman, Rick, Agoston, Agoston T, Oh, David J, Dunford, Andrew, Thorner, Aaron R, Ducar, Matthew D, Wollison, Bruce M, Coleman, Haley A, Ji, Yuan, Posner, Mitchell C, Roggin, Kevin, Turaga, Kiran, Chang, Paul, Hogarth, Kyle, Siddiqui, Uzma, Gelrud, Andres, Ha, Gavin, Freeman, Samuel S, Rhoades, Justin, Reed, Sarah, Gydush, Greg, Rotem, Denisse, Davison, Jon, Imamura, Yu, Adalsteinsson, Viktor, Lee, Jeeyun, Bass, Adam J, Catenacci, Daniel V

“…Gastroesophageal adenocarcinoma (GEA) is a lethal disease where targeted therapies, even when guided by genomic biomarkers, have had limited efficacy. A…”
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Abstract 3417: Detection and analysis of oncovirus integration sites in FFPE-derived human tumor samples using hybrid capture and massively parallel sequencing by Slevin, Michael K., Powers, Winslow T., Burns, Robert T., Wollison, Bruce M., Coleman, Haley A., Paskavitz, Amanda L., Nag, Anwesha, Manning, Danielle K., Garcia, Elizabeth, Ducar, Matthew D., Thorner, Aaron R., MacConaill, Laura E.

“…Viral genome integration into the host's genetic material can provide cells with selective advantages that make critical contributions to unregulated growth,…”
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Abstract 5695: Increased sensitivity for detection of oncogenic mutations present in circulating cell-free tumor DNA by Thorner, Aaron R., Slevin, Michael K., Clapp, Andrea, Coleman, Haley A., McShane, Suzanne R., Drinan, Samantha D., Thai, Edwin, Wollison, Bruce M., Burns, Robert T., Frieden, Alex, Ducar, Matthew D., Nag, Anwesha, MacConaill, Laura E., Meyerson, Matthew L.

“…Molecular pathways involved in tumor survival and progression are often activated by genetic alterations, and anticancer agents specifically targeting many…”
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Abstract 562: Oncovirus detection and integration analysis from human tumor samples using targeted massively parallel sequencing by Burns, Robert T., Hunter, Samuel S., Ducar, Matthew D., Thorner, Aaron R., Decaprio, James A., Hummelen, Paul Van, Frieden, Alexander, Nag, Anwesha, Coleman, Haley A., Slevin, Michael K., Clapp, Andrea, Drinan, Samantha D., McShane, Suzanne R., Thai, Edwin, Shivdasani, Priyanka, Bohannon, Joshua, Hoeftberger, Johann, Jacobs, Reuben, Wollison, Bruce M., Patel, Neil A., Manam, Monica D., Davineni, Phani, Meyerson, Matthew, MacConaill, Laura E.

“…Viruses are a major contributor to oncogenesis, causing 10-15% of human cancers. Molecular pathways involved in malignant transformation are frequently…”
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