Search Results - "Colello, Raymond J."
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Elucidating the Role of Injury-Induced Electric Fields (EFs) in Regulating the Astrocytic Response to Injury in the Mammalian Central Nervous System
Published in PloS one (12-11-2015)“…Injury to the vertebrate central nervous system (CNS) induces astrocytes to change their morphology, to increase their rate of proliferation, and to display…”
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Basic fibroblast growth factor-enhanced neurogenesis contributes to cognitive recovery in rats following traumatic brain injury
Published in Experimental neurology (01-03-2009)“…Stem/progenitor cells reside throughout the adult CNS and are actively dividing in the subventricular zone (SVZ) and the dentate gyrus (DG) of the hippocampus…”
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Two pole air gap electrospinning: Fabrication of highly aligned, three-dimensional scaffolds for nerve reconstruction
Published in Acta biomaterialia (2011)“…We describe the structural and functional properties of three-dimensional (3D) nerve guides fabricated from poly-ε-caprolactone (PCL) using the air gap…”
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The effect of epidermal growth factor in the injured brain after trauma in rats
Published in Journal of neurotrauma (01-05-2010)“…Epidermal growth factor (EGF) is a known mitogen for neural stem and progenitor cells (NS/NPCs) in the central nervous system (CNS). In vitro, EGF maintains…”
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Endogenous bioelectric fields: a putative regulator of wound repair and regeneration in the central nervous system
Published in Neural regeneration research (01-06-2016)“…Studies on a variety of highly regenerative tissues, including the central nervous system(CNS) in non-mammalian vertebrates, have consistently demonstrated…”
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Focal adhesion kinase (FAK): A regulator of CNS myelination
Published in Journal of neuroscience research (15-11-2009)“…The formation of the myelin sheath is a crucial step during development because it enables fast and efficient propagation of signals within the limited space…”
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Overexpression of Serum Response Factor Restores Ocular Dominance Plasticity in a Model of Fetal Alcohol Spectrum Disorders
Published in The Journal of neuroscience (17-02-2010)“…Neuronal plasticity deficits underlie many of the neurobehavioral problems seen in fetal alcohol spectrum disorders (FASD). Recently, we showed that third…”
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Cell proliferation and neuronal differentiation in the dentate gyrus in juvenile and adult rats following traumatic brain injury
Published in Journal of neurotrauma (01-01-2005)“…It is well known that the cognitive functions of juveniles recover to a greater extent than adult patients following traumatic brain injury (TBI). The exact…”
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Utilizing X-irradiation to selectively eliminate neural stem/progenitor cells from neurogenic regions of the mammalian brain
Published in Journal of neuroscience methods (15-05-2008)“…Neural stem/progenitor cells residing in the mammalian CNS provide a potential endogenous source for replenishing neurons that are lost due to aging, trauma or…”
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Growth conelike sensorimotor structures are characteristic features of postmigratory, premyelinating oligodendrocytes
Published in Glia (01-04-2006)“…During development, postmigratory, premyelinating oligodendrocytes extend processes that navigate through the central nervous system (CNS) environment, where…”
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Age-related proteomic changes in the subventricular zone and their association with neural stem/progenitor cell proliferation
Published in Journal of neuroscience research (01-06-2012)“…In the mammalian central nervous system, generation of new neurons persists in the subventricular zone (SVZ) throughout life. However, the capacity for…”
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Anatomical integration of newly generated dentate granule neurons following traumatic brain injury in adult rats and its association to cognitive recovery
Published in Experimental neurology (01-03-2007)“…The hippocampus is particularly vulnerable to traumatic brain injury (TBI), the consequences of which are manifested as learning and memory deficits. Following…”
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The incorporation of growth factor and chondroitinase ABC into an electrospun scaffold to promote axon regrowth following spinal cord injury
Published in Journal of tissue engineering and regenerative medicine (01-08-2016)“…Spinal cord injury results in tissue necrosis in and around the lesion site, commonly leading to the formation of a fluid‐filled cyst. This pathological end…”
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Enhanced hippocampal neurogenesis by intraventricular S100B infusion is associated with improved cognitive recovery after traumatic brain injury
Published in Journal of neurotrauma (01-06-2005)“…Evidence of injury-induced neurogenesis in the adult hippocampus suggests that an endogenous repair mechanism exists for cognitive dysfunction following…”
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FTY720 reduces inflammation and promotes functional recovery after spinal cord injury
Published in Journal of neurotrauma (01-12-2009)“…A robust and complex inflammatory cascade is known to be a prominent component of secondary injury following spinal cord injury (SCI). Specifically, the…”
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Spontaneous optic nerve compression in the osteopetrotic (op/op) mouse: a novel model of myelination failure
Published in The Journal of neuroscience (20-02-2013)“…We report a focal disturbance in myelination of the optic nerve in the osteopetrotic (op/op) mouse, which results from a spontaneous compression of the nerve…”
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Aging- and injury-related differential apoptotic response in the dentate gyrus of the hippocampus in rats following brain trauma
Published in Frontiers in aging neuroscience (2013)“…The elderly are among the most vulnerable to traumatic brain injury (TBI) with poor functional outcomes and impaired cognitive recovery. Of the pathological…”
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Developmental expression of the prion protein gene in glial cells
Published in Neuron (Cambridge, Mass.) (01-03-1995)“…Replication of prions is dependent on the presence of the host protein PrP c. During the course of disease, PrP c is converted into an abnormal isoform, PrP…”
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Confocal laser scanning microscopic photoconversion: a new method to stabilize fluorescently labeled cellular elements for electron microscopic analysis
Published in Current protocols in neuroscience (2012)“…Photoconversion, the method by which a fluorescent dye is transformed into a stable, osmiophilic product that can be visualized by electron microscopy, is the…”
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Photoconversion using confocal laser scanning microscopy: A new tool for the ultrastructural analysis of fluorescently labeled cellular elements
Published in Journal of neuroscience methods (30-08-2007)“…Photoconversion, the method by which a fluorescent dye is transformed into a stable, osmiophilic product that can be visualized by transmission electron…”
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