Search Results - "Colella, Marina P"
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Key endothelial cell angiogenic mechanisms are stimulated by the circulating milieu in sickle cell disease and attenuated by hydroxyurea
Published in Haematologica (Roma) (01-06-2015)“…As hypoxia-induced inflammatory angiogenesis may contribute to the manifestations of sickle cell disease, we compared the angiogenic molecular profiles of…”
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Elevated hypercoagulability markers in hemoglobin SC disease
Published in Haematologica (Roma) (01-04-2015)“…Hemoglobin SC disease is a very prevalent hemoglobinopathy; however, very little is known about this condition specifically. There appears to be an increased…”
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Crizanlizumab for the Prevention of Pain Crises in Sickle Cell Disease
Published in The New England journal of medicine (02-02-2017)“…In this yearlong trial involving patients with sickle cell disease, crizanlizumab, an antibody to P-selectin, was associated with a 45% lower rate of pain…”
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A retrospective analysis of 122 immune thrombocytopenia patients treated with dapsone: Efficacy, safety and factors associated with treatment response
Published in Journal of thrombosis and haemostasis (01-09-2021)“…Background The optimum second‐line treatment or best sequence of treatments for immune thrombocytopenia (ITP) are yet to be determined. Our institution has…”
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Aquatic exercise in patients with haemophilia: Electromyographic and functional results from a prospective cohort study
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-03-2021)“…Introduction Recurrent joint bleeds in haemophilia patients often cause musculoskeletal changes leading to functional capacity impairment. Aim In this study,…”
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Residual Vein Thrombosis Echogenicity Is Associated to the Risk of DVT Recurrence: A Cohort Study
Published in Clinical and applied thrombosis/hemostasis (01-04-2018)“…Although deep vein thrombosis (DVT) recurrence is a common late complication of the disease, there are few predictive markers to risk-stratify patients…”
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Elevated plasma levels and platelet-associated expression of the pro-thrombotic and pro-inflammatory protein, TNFSF14 (LIGHT), in sickle cell disease
Published in British journal of haematology (01-09-2012)“…Summary Chronic vascular inflammation and endothelial activation may initiate vaso‐occlusion in sickle cell disease (SCD). TNFSF14 (CD258; LIGHT), a…”
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Severe postthrombotic syndrome is associated with characteristic sonographic pattern of the residual thrombosis
Published in Blood coagulation & fibrinolysis (01-09-2016)“…Postthrombotic syndrome (PTS) may affect 50% of patients with deep venous thrombosis, 5–10% of them may present severe manifestations. The causes for PTS…”
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Performance of a point-of-care device in determining prothrombin time in an anticoagulation clinic
Published in Blood coagulation & fibrinolysis (01-03-2012)“…New portable devices for the measurement of the prothrombin time and the international normalized ratio (INR) from capillary blood samples have demonstrated to…”
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Acquired Hemophilia a Relapse Is Related to Th2 Response, and Increased Expression of B-Cell Activating Factor (BAFF)
Published in Blood (23-11-2021)“…Acquired hemophilia A (AHA) is a rare autoimmune disorder caused by the development of autoantibodies against the factor (F)VIII of coagulation with higher…”
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Impact of Two Immobilized GPIbα Assays in the Diagnosis of Von Willebrand Disease
Published in Blood (06-12-2014)“…The diagnosis of von Willebrand Disease (VWD) remains a challenge of daily hematology practice. Ristocetin cofactor activity (VWF:RCo) is an important…”
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Lower Echogenicity of the Residual Venous Thrombosis at Ultrasound Examination Is Associated to Recurrent Thrombosis Events
Published in Blood (06-12-2014)“…Introduction: After the first thrombotic event, up to 30% of deep venous thrombosis (DVT) cases may recur within 10 years. Unprovoked first DVT episode, male…”
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Six Novel Mutations Identified in the Glycoproteins Ib Alpha, Ib Beta and IX Genes Among Twenty-Two Unrelated Patients with Bernard-Soulier Syndrome in Brazil
Published in Blood (18-11-2011)“…Abstract 1156▪▪This icon denotes a clinically relevant abstract Bernard-Soulier syndrome (BSS) is a rare hereditary bleeding disorder, caused by mutations…”
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Comparative Evaluation of Five Different Assays for Ristocetin Cofactor Activity Determination
Published in Blood (18-11-2011)“…Abstract 3317 Despite significant advances in the comprehension of the molecular pathogenesis of Von Willebrand Disease (VWD), the diagnosis of this condition…”
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Hydroxyurea Reduces the Hypercoagulable State In Sickle Cell Anemia
Published in Blood (18-11-2011)“…Abstract 1068 Sickle cell anemia (SCA) is associated with a hypercoagulable state, through mechanisms not yet clearly defined. SCA patients present an elevated…”
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Elevation of Hypercoagulability Markers in Hemoglobin SC Disease
Published in Blood (16-11-2012)“…Abstract 3227 Sickle cell anemia (SCA) patients present an elevated rate of thrombotic complications and increased biological markers of hemostatic activation…”
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Elevated plasma levels and platelet‐associated expression of the pro‐thrombotic and pro‐inflammatory protein, T NFSF14 (LIGHT), in sickle cell disease
Published in British journal of haematology (01-09-2012)“…Summary Chronic vascular inflammation and endothelial activation may initiate vaso‐occlusion in sickle cell disease ( SCD ). TNFSF 14 ( CD 258; LIGHT ), a…”
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Journal Article