Search Results - "Cole, S.A."

Impact of DISC1 variation on neuroanatomical and neurocognitive phenotypes by Carless, M A, Glahn, D C, Johnson, M P, Curran, J E, Bozaoglu, K, Dyer, T D, Winkler, A M, Cole, S A, Almasy, L, MacCluer, J W, Duggirala, R, Moses, E K, Göring, H H H, Blangero, J

“…Although disrupted in schizophrenia 1 ( DISC1 ) has been implicated in many psychiatric disorders, including schizophrenia, bipolar disorder, schizoaffective…”
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A Quantitative Trait Locus on Chromosome 16q Influences Variation in Plasma HDL-C Levels in Mexican Americans by Mahaney, M C, Almasy, L, Rainwater, D L, VandeBerg, J L, Cole, S A, Hixson, J E, Blangero, J, MacCluer, J W

“…OBJECTIVE—We conducted a whole-genome, multipoint linkage screen to localize a previously reported major locus accounting for 56% to 67% of the additive…”
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Childhood bone strength shows genetic linkage to chromosomes 2, 4 and 12: Results from the Fels Longitudinal Study by Duren, D.L, Blangero, J, Sherwood, R.J, Dyer, T, Cole, S.A, Czerwinski, S.A, Chumlea, W.C, Sun, S.S, Demerath, E.W, Siervogel, R.M, Towne, B

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The association of genetic variants of type 2 diabetes with kidney function by Franceschini, Nora, Shara, Nawar M, Wang, Hong, Voruganti, V Saroja, Laston, Sandy, Haack, Karin, Lee, Elisa T, Best, Lyle G, Maccluer, Jean W, Cochran, Barbara J, Dyer, Thomas D, Howard, Barbara V, Cole, Shelley A, North, Kari E, Umans, Jason G

“…Type 2 diabetes is highly prevalent and is the major cause of progressive chronic kidney disease in American Indians. Genome-wide association studies…”
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Plasminogen activator inhibitor‐1 is associated with leukocyte telomere length in American Indians: findings from the Strong Heart Family Study by Peng, H., Yeh, F., Lin, J., Best, L. G., Cole, S. A., Lee, E. T., Howard, B. V., Zhao, J.

“…Essentials Plasminogen activator inhibitor‐1 (PAI‐1) advanced cellular senescence in experiment studies. No population study exists on the association between…”
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Transcriptomics of cortical gray matter thickness decline during normal aging by Kochunov, P., Charlesworth, J., Winkler, A., Hong, L.E., Nichols, T.E., Curran, J.E., Sprooten, E., Jahanshad, N., Thompson, P.M., Johnson, M.P., Kent, J.W., Landman, B.A., Mitchell, B., Cole, S.A., Dyer, T.D., Moses, E.K., Goring, H.H.H., Almasy, L., Duggirala, R., Olvera, R.L., Glahn, D.C., Blangero, J.

“…We performed a whole-transcriptome correlation analysis, followed by the pathway enrichment and testing of innate immune response pathway analyses to evaluate…”
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Brain-derived neurotrophic factor in human subjects with function-altering melanocortin-4 receptor variants by Hohenadel, M G, Thearle, M S, Grice, B A, Huang, H, Dai, M-H, Tao, Y-X, Hunter, L A, Palaguachi, G I, Mou, Z, Kim, R C, Tsang, M M, Haack, K, Voruganti, V S, Cole, S A, Butte, N F, Comuzzie, A G, Muller, Y L, Baier, L J, Krakoff, J, Knowler, W C, Yanovski, J A, Han, J C

“…Background: In rodents, hypothalamic brain-derived neurotrophic factor (BDNF) expression appears to be regulated by melanocortin-4 receptor (MC4R) activity…”
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Observations regarding the immunogenicity of BDD‐rFVIII derived from a mechanistic personalized medicine perspective by SAUNA, Z. E., AMERI, A., KIM, B., YANOVER, C., VIEL, K. R., RAJALINGAM, R., COLE, S. A., HOWARD, T. E.

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baboon as a nonhuman primate model for the study of the genetics of obesity by Comuzzie, A.G, Cole, S.A, Martin, L, Carey, K.D, Mahaney, M.C, Blangero, J, VandeBerg, J.L

“…Objective: At present, rodents represent the most common animal model for research in obesity and its comorbidities (e.g., type 2 diabetes and coronary heart…”
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Cytokine and antibody subclass responses in the intestinal lymph of sheep during repeated experimental infections with the nematode parasite Trichostrongylus colubriformis by Pernthaner, Anton, Cole, Sally-Ann, Morrison, Lilian, Green, Richard, Shaw, Richard J., Hein, Wayne R.

“…The expression of interleukin (IL)-4, IL-5, IL-10, IL-13, TNF-α and IFN-γ genes, and parasite-specific IgM, IgG1, IgG2, IgA and total IgE levels, were…”
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Localization of a major susceptibility locus influencing preterm birth by Chittoor, G, Farook, V S, Puppala, S, Fowler, S P, Schneider, J, Dyer, T D, Cole, S A, Lynch, J L, Curran, J E, Almasy, L, Maccluer, J W, Comuzzie, A G, Hale, D E, Ramamurthy, R S, Dudley, D J, Moses, E K, Arya, R, Lehman, D M, Jenkinson, C P, Bradshaw, B S, Defronzo, R A, Blangero, J, Duggirala, R

“…Preterm birth (PTB) is a complex trait, but little is known regarding its major genetic determinants. The objective of this study is to localize genes that…”
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Quantitative trait locus determining dietary macronutrient intakes is located on human chromosome 2p22. [Erratum: 2006 Oct., v. 84, no. 4, p. 950.] by Cai, G, Cole, S.A, Bastarrachea, R.A, MacCluer, J.W, Blangero, J, Comuzzie, A.G

“…Background: Obesity is generally accompanied by increased food intake. Objective: We sought to identify the genes influencing variation in dietary…”
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Genome-wide scan revealed genetic loci for energy metabolism in Hispanic children and adolescents by Cai, G, Cole, S.A, Butte, N.F, Voruganti, V.S, Comuzzie, A.G

“…Objective: Genome-wide scans were conducted in search for genetic locations linked to energy expenditure and substrate oxidation in children. Design: Pedigreed…”
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Linkage analysis of circulating levels of adiponectin in hispanic children by Tejero, M.E, Cai, G, Goring, H.H.H, Diego, V, Cole, S.A, Bacino, C.A, Butte, N.F, Comuzzie, A.G

“…Introduction: Adiponectin, a hormone produced exclusively by adipose tissue, is inversely associated with insulin resistance and proinflammatory conditions…”
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Genome-wide linkage scan for quantitative trait loci underlying normal variation in heel bone ultrasound measures by Lee, Miryoung, Choh, A. C., Williams, K. D., Schroeder, V., Dyer, T. D., Blangero, J., Cole, S. A., Chumlea, W. M. C., Duren, D. L., Sherwood, R. J., Siervogel, R. M., Towne, B., Czerwinski, S. A.

“…Quantitative ultrasound (QUS) traits are correlated with bone mineral density (BMD), but predict risk for future fracture independent of BMD. Only a few…”
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Linkage analysis of LDL cholesterol in American Indian populations: the Strong Heart Family Study by North, K. E, Goring, H. H. H, Cole, S. A, Diego, V. P, Almasy, L, Laston, S, Cantu, T, Howard, B. V, Lee, E. T, Best, L. G, Fabsitz, R. R, MacCluer, J. W

“…Previous studies have demonstrated that low density lipoprotein cholesterol (LDL-C) concentration is influenced by both genes and environment. Although rare…”
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Linkage analysis of LDL cholesterol in American Indian populations: the Strong Heart Family Studys by K.E. North, H.H.H. Göring, S.A. Cole, V.P. Diego, L. Almasy, S. Laston, T. Cantu, B.V. Howard, E.T. Lee, L.G. Best, R.R. Fabsitz, J.W. MacCluer

“…Previous studies have demonstrated that low density lipoprotein cholesterol (LDL-C) concentration is influenced by both genes and environment. Although rare…”
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Adiponectin but not resistin is associated with insulin resistance-related phenotypes in baboons by Tejero, M.E, Freeland-Graves, J.H, Proffitt, J.M, Peebles, K.W, Cai, G, Cole, S.A, Comuzzie, A.G

“…Objectives: The hormones adiponectin and resistin have been associated with insulin resistance. This paper analyzed the potential relationship between…”
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Genetics of leptin expression in baboons by Cole, S.A, Martin, L.J, Peebles, K.W, Leland, M.M, Rice, K, VandeBerg, J.L, Blangero, J, Comuzzie, A.G

“…OBJECTIVE: Leptin gene expression is higher in females than in males, and is regulated by many factors including energy intake and insulin, but little is known…”
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Quantitative genetic analysis of glucose transporter 4 mRNA levels in baboon adipose by Tejero, M.E, Proffitt, J.M, Cole, S.A, Freeland-Graves, J.H, Cai, G, Peebles, K.W, Cox, L.A, Mahaney, M.C, Rogers, J, VandeBerg, J.L

“…Objective: Glucose transporter 4 (GLUT4) is an insulin‐responsive glucose transporter expressed in adipose tissue. A decrease of the mRNA abundance of GLUT4 in…”
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