Search Results - "Cole, S."
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CAT tails drive degradation of stalled polypeptides on and off the ribosome
Published in Nature structural & molecular biology (01-06-2019)“…Stalled translation produces incomplete, ribosome-tethered polypeptides that the ribosome-associated quality control (RQC) pathway targets for degradation via…”
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Detection and Degradation of Stalled Nascent Chains via Ribosome-Associated Quality Control
Published in Annual review of biochemistry (20-06-2020)“…Stalled protein synthesis produces defective nascent chains that can harm cells. In response, cells degrade these nascent chains via a process called…”
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Higher-Order Topology and Nodal Topological Superconductivity in Fe(Se,Te) Heterostructures
Published in Physical review letters (17-10-2019)“…We show, theoretically, that a heterostructure of monolayer FeTe1−xSex-a superconducting quantum spin Hall material-with a monolayer of FeTe-a bicollinear…”
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Helical Hinge Majorana Modes in Iron-Based Superconductors
Published in Physical review letters (10-05-2019)“…Motivated by recent experiments on FeTe_{1-x}Se_{x}, we construct an explicit minimal model of an iron-based superconductor with band inversion at the Z point…”
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Asc1, Hel2, and Slh1 couple translation arrest to nascent chain degradation
Published in RNA (Cambridge) (01-05-2017)“…Premature arrest of protein synthesis within the open reading frame elicits a protective response that degrades the incomplete nascent chain. In this response,…”
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The Canadian Earth System Model version 5 (CanESM5.0.3)
Published in Geoscientific Model Development (25-11-2019)“…The Canadian Earth System Model version 5 (CanESM5) is a global model developed to simulate historical climate change and variability, to make centennial-scale…”
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7
KCNMA1 -linked channelopathy
Published in The Journal of general physiology (07-10-2019)“…encodes the pore-forming α subunit of the "Big K " (BK) large conductance calcium and voltage-activated K channel. BK channels are widely distributed across…”
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Isotopic advances in understanding reactive nitrogen deposition and atmospheric processing
Published in The Science of the total environment (20-04-2019)“…Recent advances in stable isotope measurements now allow for detailed investigations of the sources, transformations, and deposition of reactive nitrogen (N)…”
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Holstein Friesian dairy cattle edited for diluted coat color as a potential adaptation to climate change
Published in BMC genomics (26-11-2021)“…High-producing Holstein Friesian dairy cattle have a characteristic black and white coat, often with large proportions of black. Compared to a light coat…”
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Physiologically based pharmacokinetic modeling in regulatory decision‐making at the European Medicines Agency
Published in Clinical pharmacology and therapeutics (01-07-2017)“…Physiologically based pharmacokinetic (PBPK) modeling is a valuable tool in drug development and regulatory assessment, as it offers the opportunity to…”
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Going Virtual: Transitioning an Older Adult Community Health Clinical Course to Online During COVID-19
Published in The Journal of nursing education (01-05-2024)“…Nursing students in a community health course implemented a quality improvement project with active older adults (AOA). This article describes a process for…”
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Exercise Intolerance in Heart Failure With Preserved Ejection Fraction: Diagnosing and Ranking Its Causes Using Personalized O 2 Pathway Analysis
Published in Circulation (New York, N.Y.) (09-01-2018)“…Heart failure with preserved ejection fraction (HFpEF) is a common syndrome with a pressing shortage of therapies. Exercise intolerance is a cardinal symptom…”
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13
The science of pipe corrosion: A review of the literature on the corrosion of ferrous metals in soils
Published in Corrosion science (01-03-2012)“…The paper reviews the literature that may assist in forming a multiscale model of corrosion in soils. This model should take into account macro-environmental…”
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Exercise Intolerance in Heart Failure With Preserved Ejection Fraction: Diagnosing and Ranking Its Causes Using Personalized O2 Pathway Analysis
Published in Circulation (New York, N.Y.) (09-01-2018)“…BACKGROUND:Heart failure with preserved ejection fraction (HFpEF) is a common syndrome with a pressing shortage of therapies. Exercise intolerance is a…”
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15
Leader-Team Congruence in Power Distance Values and Team Effectiveness: The Mediating Role of Procedural Justice Climate
Published in Journal of applied psychology (01-11-2013)“…We examine the effect of (in)congruence between leaders' and teams' power distance values on team effectiveness. We hypothesize that the (in)congruence between…”
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Effects of large induced superconducting gap on semiconductor Majorana nanowires
Published in Physical review. B, Condensed matter and materials physics (12-11-2015)“…With the recent achievement of extremely high-quality epitaxial interfaces between InAs nanowires and superconducting Al shells with strong…”
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Volcanic contribution to decadal changes in tropospheric temperature
Published in Nature geoscience (01-03-2014)“…Global mean surface and tropospheric temperatures have shown slower warming since 1998 than found in climate model simulations. A detailed analysis of…”
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Functions of spontaneous and voluntary future thinking: evidence from subjective ratings
Published in Psychological research (01-06-2021)“…Future thinking is defined as the ability to withdraw from reality and mentally project oneself into the future. The primary aim of the present study was to…”
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Origin and evolution of the octoploid strawberry genome
Published in Nature genetics (01-03-2019)“…Cultivated strawberry emerged from the hybridization of two wild octoploid species, both descendants from the merger of four diploid progenitor species into a…”
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Feasibility Cues during a Sexual Encounter Impact the Strength of Heterosexual Women's Orgasm Goal Pursuit
Published in The Journal of sex research (12-02-2024)“…The "orgasm gap" for women who have sex with men remains a pressing gender equity issue. Recent research found that women who pursued orgasm as a goal were…”
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