Search Results - "Cole, P.A."

LSD1 Histone Demethylase Assays and Inhibition by Hayward, D, Cole, P A

“…The lysine-specific demethylase (LSD1) is a flavin-dependent amine oxidase that selectively removes one or two methyl groups from histone H3 at the Lys4…”
Get more information

Ghrelin by Müller, T.D, Nogueiras, R, Andermann, M.L, Andrews, Z.B, Anker, S.D, Argente, J, Batterham, R.L, Benoit, S.C, Bowers, C.Y, Broglio, F, Casanueva, F.F, D'Alessio, D, Depoortere, I, Geliebter, A, Ghigo, E, Cole, P.A, Cowley, M, Cummings, D.E, Dagher, A, Diano, S, Dickson, S.L, Diéguez, C, Granata, R, Grill, H.J, Grove, K, Habegger, K.M, Heppner, K, Heiman, M.L, Holsen, L, Holst, B, Inui, A, Jansson, J.O, Kirchner, H, Korbonits, M, Laferrère, B, LeRoux, C.W, Lopez, M, Morin, S, Nakazato, M, Nass, R, Perez-Tilve, D, Pfluger, P.T, Schwartz, T.W, Seeley, R.J, Sleeman, M, Sun, Y, Sussel, L, Tong, J, Thorner, M.O, van der Lely, A.J, van der Ploeg, L.H.T, Zigman, J.M, Kojima, M, Kangawa, K, Smith, R.G, Horvath, T, Tschöp, M.H

“…Abstract Background The gastrointestinal peptide hormone ghrelin was discovered in 1999 as the endogenous ligand of the growth hormone secretagogue receptor…”
Get full text

The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia by Giotopoulos, G, Chan, W-I, Horton, S J, Ruau, D, Gallipoli, P, Fowler, A, Crawley, C, Papaemmanuil, E, Campbell, P J, Göttgens, B, Van Deursen, J M, Cole, P A, Huntly, B J P

“…Growing evidence links abnormal epigenetic control to the development of hematological malignancies. Accordingly, inhibition of epigenetic regulators is…”
Get full text

Real-time analysis of the thermal oxidation of polyolefins by FT-IR emission by George, G.A., Celina, M., Vassallo, A.M., Cole-Clarke, P.A.

“…Quantitative FTIR-emission spectroscopy was applied to investigate the real-time thermal oxidation of polyolefin samples and shown to be a useful method for…”
Get full text

Discovery of Entry Inhibitors for HIV-1 via a New De Novo Protein Design Framework by Bellows, M.L., Taylor, M.S., Cole, P.A., Shen, L., Siliciano, R.F., Fung, H.K., Floudas, C.A.

“…A new (to our knowledge) de novo design framework with a ranking metric based on approximate binding affinity calculations is introduced and applied to the…”
Get full text

Less invasive stabilization system (LISS) for fractures of the proximal tibia: Indications, Surgical Technique and Preliminary Results of the UMC Clinical Trial by Cole, P.A., Zlowodzki, M., Kregor, P.J.

“…The surgical treatment of proximal tibia fractures, with or without intraarticular involvement, is associated with well-described patterns of failure and…”
Get full text

Fixation of distal femoral fractures above total knee arthroplasty utilizing the Less Invasive Stabilization System (L.I.S.S.) by Kregor, P.J., Hughes, J.L., Cole, P.A.

“…Supracondylar femoral fractures above total knee arthroplasty remain a treatment challenge. Complication rates as high as 30% are associated with both…”
Get full text

Distal femoral fracture fixation utilizing the Less Invasive Stabilization System (L.I.S.S.): The technique and early results by Kregor, P.J., Stannard, J., Zlowodzki, M., Cole, P.A., Alonso, J.

“…The treatment of supracondylar femoral fractures in the past three decades has evolved from non-operative to operative treatment. While operative fixation…”
Get full text

Maisonneuve Fracture Equivalent with Proximal Tibiofibular Dislocation: A Case Report and Literature Review by Levy, B.A., Vogt, K.J., Herrera, D.A., Cole, P.A.

Get full text

Compartment Pressures after Submuscular Fixation of Proximal Tibia Fractures by Cole, P.A., Zlowodzki, M., Kregor, P.J.

Get full text

The impact of manpower, personnel, and training (MPT) on life cycle cost (Air Force management) by Cole, P.A.

“…The author outlines all of the different elements of MPT costs that are considered during the O&S (operating and support) portion of an LCC (life cycle cost)…”
Get full text