Search Results - "Cole, Laurence A."

Biological functions of hCG and hCG-related molecules by Cole, Laurence A

“…hCG is a term referring to 4 independent molecules, each produced by separate cells and each having completely separate functions. These are hCG produced by…”
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hCG, the wonder of today's science by Cole, Laurence A

“…hCG is a wonder. Firstly, because hCG is such an extreme molecule. hCG is the most acidic glycoprotein containing the highest proportion of sugars. Secondly,…”
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New discoveries on the biology and detection of human chorionic gonadotropin by Cole, Laurence A

“…Human chorionic gonadotropin (hCG) is a glycoprotein hormone comprising 2 subunits, alpha and beta joined non covalently. While similar in structure to…”
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The normal variabilities of the menstrual cycle by Cole, Laurence A., Ph.D, Ladner, Donald G., M.D, Byrn, Francis W., M.D

“…Objective To address conflicts in the normal variabilities of the menstrual cycle using the newest generation test methods and to establish normal ranges for…”
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Hyperglycosylated human chorionic gonadotropin and the source of pregnancy failures by Sasaki, Yasushi, M.D., Ph.D, Ladner, Donald G., M.D, Cole, Laurence A., Ph.D

“…Objective To investigate the proportion of hyperglycosylated human chorionic gonadotropin (hCG-H) produced at the time of implantation as a predictor of…”
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Gestational trophoblastic diseases: 1. Pathophysiology of hyperglycosylated hCG by Cole, Laurence A., Dai, Donghai, Butler, Stephen A., Leslie, Kimberly K., Kohorn, Ernest I.

“…Hyperglycosylated hCG (hCG-H) is a glycosylation variant of hCG produced by cytotrophoblast cells at implantation of pregnancy and in choriocarcinoma. We…”
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Normal Production of Human Chorionic Gonadotropin in Menopause by Cole, Laurence A, Sasaki, Yasushi, Muller, Carolyn Y

“…To the Editor: A positive test for the presence of human chorionic gonadotropin (hCG) before menopause is an indication of pregnancy. 1 A positive hCG test in…”
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Direct analysis of hCGβcf glycosylation in normal and aberrant pregnancy by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry by Iles, Ray K, Cole, Laurence A, Butler, Stephen A

“…The analysis of human chorionic gonadotropin (hCG) in clinical chemistry laboratories by specific immunoassay is well established. However, changes in…”
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Immunoassay of human chorionic gonadotropin, its free subunits, and metabolites by Cole, Laurence A

“…Multiple hCG-related molecules are present in pregnancy serum and urine samples. These include non-nicked hCG (the hormone), nicked hCG, hyper- and…”
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hCG, five independent molecules by Cole, Laurence A.

“…The hCG amino acid sequence supports 5 glycoproteins. All are called hCG forms. This review examines all 5 molecules, the hormone as produced by the placental…”
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Hyperglycosylated hCG, hCGβ and Hyperglycosylated hCGβ: Interchangeable cancer promoters by Cole, Laurence A., Butler, Stephen

“…► This article examines and shows that Hyperglycosylated hCG, Hyperglycosylated hCGβ and hCGβ are interchangeable in choriocarcinoma, bladder and endometrial…”
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Detection of perimenopause or postmenopause human chorionic gonadotropin: an unnecessary source of alarm by Cole, Laurence A., PhD, Khanlian, Sarah A., MPH, Muller, Carolyn Y., MD

“…Objective The normal pituitary production of human chorionic gonadotropin alongside luteinizing hormone, measurable in menopausal serum and urine was initially…”
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Hyperglycosylated hCG and pregnancy failures by Cole, Laurence A

“…Abstract Considerable evidence indicates that one third of early pregnancy failures, spontaneous abortions and biochemical pregnancies, are due to chromosomal…”
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WITHDRAWN: Value of home ovulation tests by Cole, Laurence A., Ph.D, Byrn, Francis W., M.D

“…This article has been withdrawn consistent with Elsevier Policy on Article Withdrawal. ( http://www.elsevier.com/locate/withdrawalpolicy ). The Publisher…”
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The hCG assay or pregnancy test by Cole, Laurence A

“…This review examines human chorionic gonadotropin (hCG) or pregnancy tests from multiple perspectives. It first investigates the molecule hCG and shows that…”
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Choriocarcinoma and gestational trophoblastic disease by Smith, Harriet O, Kohorn, Ernest, Cole, Laurence A

“…Gestational trophoblastic disease (GTD) encompasses a unique group of uncommon but interrelated conditions derived from placental trophoblasts. For the…”
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The utility of six over-the-counter (home) pregnancy tests by Cole, Laurence A

“…The home pregnancy market is rapidly evolving. It has moved from detection of pregnancy on the day of missed menstrual bleeding, to detection claims 4 days…”
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Proportion hyperglycosylated hCG: a new test for discriminating gestational trophoblastic diseases by Cole, Laurence A

“…Hyperglycosylated human chorionic gonadotropin (hCG) is a variant of hCG with large oligosaccharide side chains. Although hCG is produced by…”
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Familial hCG Syndrome by Cole, Laurence A

“…Abstract An explanation is needed for why some men and women show positive in hCG screening tests when they are not pregnant, do not have cancer and are…”
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Individual deviations in human chorionic gonadotropin concentrations during pregnancy by Cole, Laurence A.

“…Serum and urine human chorionic gonadotropin (hCG) vary greatly during the course of pregnancy. We investigated the cause of this variation. Eighty-two women…”
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