Search Results - "Cole, Bonnie L."

Modular skeletal evolution in sticklebacks is controlled by additive and clustered quantitative trait Loci by Miller, Craig T, Glazer, Andrew M, Summers, Brian R, Blackman, Benjamin K, Norman, Andrew R, Shapiro, Michael D, Cole, Bonnie L, Peichel, Catherine L, Schluter, Dolph, Kingsley, David M

“…Understanding the genetic architecture of evolutionary change remains a long-standing goal in biology. In vertebrates, skeletal evolution has contributed…”
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Therapeutic HDAC inhibition in hypermutant diffuse intrinsic pontine glioma by Noll, Alyssa, Myers, Carrie, Biery, Matthew C, Meechan, Michael, Tahiri, Sophie, Rajendran, Asmitha, Berens, Michael E, Paine, Danyelle, Byron, Sara, Zhang, Jiaming, Winter, Conrad, Pakiam, Fiona, Leary, Sarah E S, Cole, Bonnie L, Jackson, Evangeline R, Dun, Matthew D, Foster, Jessica B, Evans, Myron K, Pattwell, Siobhan S, Olson, James M, Vitanza, Nicholas A

“…Constitutional mismatch repair deficiency (CMMRD) is a cancer predisposition syndrome associated with the development of hypermutant pediatric high-grade…”
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Mutations of the DNA repair gene PNKP in a patient with microcephaly, seizures, and developmental delay (MCSZ) presenting with a high-grade brain tumor by Jiang, Bingcheng, Murray, Cameron, Cole, Bonnie L., Glover, J. N. Mark, Chan, Gordon K., Deschenes, Jean, Mani, Rajam S., Subedi, Sudip, Nerva, John D., Wang, Anthony C., Lockwood, Christina M., Mefford, Heather C., Leary, Sarah E. S., Ojemann, Jeffery G., Weinfeld, Michael, Ene, Chibawanye I.

“…Polynucleotide Kinase-Phosphatase (PNKP) is a bifunctional enzyme that possesses both DNA 3′-phosphatase and DNA 5′-kinase activities, which are required for…”
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Looking beyond year 1 in the molecular era of pediatric brain tumor diagnosis: confirmatory testing of germline variants found on tumor sequencing by Greene, Brittany L, Stasi, Shannon M, Ting, Michelle A, Waligorski, Natalie, Cole, Bonnie L, Lockwood, Christina M, Paulson, Vera A, Buchan, Jillian G, Lee, Amy, Ojemann, Jeffrey G, Ellenbogen, Richard G, Stevens, Jeffrey, Leary, Sarah E S

“…Somatic molecular profiling of pediatric brain tumors aids with the diagnosis and treatment of patients with a variety of high- and low-grade central nervous…”
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The genetic architecture of divergence between threespine stickleback species by Kingsley, David M, Peichel, Catherine L, Nereng, Kirsten S, Ohgi, Kenneth A, Cole, Bonnie L. E, Colosimo, Pamela F, Buerkle, C. Alex, Schluter, Dolph

“…The genetic and molecular basis of morphological evolution is poorly understood, particularly in vertebrates. Genetic studies of the differences between…”
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The “SEED” Study: The Feasibility of Selecting Patient-Specific Biologically Targeted Therapy with Sorafenib, Everolimus, Erlotinib or Dasatinib for Pediatric and Young Adult Patients with Recurrent or Refractory Brain Tumors by Cole, Bonnie L., Starr, Kimberly, Lockwood, Christina M., Leary, Sarah E. S.

“…BACKGROUNDPediatric brain tumors are the leading cause of cancer death in children and represent a variety of diseases and molecular subtypes. This study…”
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Neuropathology of Pediatric Brain Tumors: A Concise Review by Cole, Bonnie L

“…Pediatric brain tumors are an incredibly diverse group of neoplasms and neuropathological tumor classification is an essential part of patient care…”
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Correction to: Heme oxygenase-1 deficiency presenting with interstitial lung disease and hemophagocytic flares by Chau, Alice S, Cole, Bonnie L, Debley, Jason S, Nanda, Kabita, Rosen, Aaron B I, Bamshad, Michael J, Nickerson, Deborah A, Torgerson, Troy R, Allenspach, Eric J

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Heme oxygenase-1 deficiency presenting with interstitial lung disease and hemophagocytic flares by Chau, Alice S, Cole, Bonnie L, Debley, Jason S, Nanda, Kabita, Rosen, Aaron B I, Bamshad, Michael J, Nickerson, Deborah A, Torgerson, Troy R, Allenspach, Eric J

“…Heme oxygenase-1 (HMOX1) catalyzes the metabolism of heme into carbon monoxide, ferrous iron, and biliverdin. Through biliverdin reductase, biliverdin becomes…”
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Intraventricular B7-H3 CAR T Cells for Diffuse Intrinsic Pontine Glioma: Preliminary First-in-Human Bioactivity and Safety by Vitanza, Nicholas A, Wilson, Ashley L, Huang, Wenjun, Seidel, Kristy, Brown, Christopher, Gustafson, Joshua A, Yokoyama, Jason K, Johnson, Adam J, Baxter, Blake A, Koning, Ryan W, Reid, Aquene N, Meechan, Michael, Biery, Matthew C, Myers, Carrie, Rawlings-Rhea, Stephanie D, Albert, Catherine M, Browd, Samuel R, Hauptman, Jason S, Lee, Amy, Ojemann, Jeffrey G, Berens, Michael E, Dun, Matthew D, Foster, Jessica B, Crotty, Erin E, Leary, Sarah E S, Cole, Bonnie L, Perez, Francisco A, Wright, Jason N, Orentas, Rimas J, Chour, Tony, Newell, Evan W, Whiteaker, Jeffrey R, Zhao, Lei, Paulovich, Amanda G, Pinto, Navin, Gust, Juliane, Gardner, Rebecca A, Jensen, Michael C, Park, Julie R

“…Diffuse intrinsic pontine glioma (DIPG) remains a fatal brainstem tumor demanding innovative therapies. As B7-H3 (CD276) is expressed on central nervous system…”
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Primary choriocarcinoma of the bilateral basal ganglia presenting in a teenaged male by Perry, Brandon C., MD, Perez, Francisco A., MD, PhD, Nixon, Jason N., MD, Cole, Bonnie L., MD, Ishak, Gisele, MD

“…Abstract Primary intracranial choriocarcinoma (PICCC), a type of germ-cell tumor, is a very rare primary tumor of the central nervous system that generally…”
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Optimal therapeutic targeting by HDAC inhibition in biopsy-derived treatment-naïve diffuse midline glioma models by Vitanza, Nicholas A, Biery, Matt C, Myers, Carrie, Ferguson, Eric, Zheng, Ye, Girard, Emily J, Przystal, Justyna M, Park, Giulia, Noll, Alyssa, Pakiam, Fiona, Winter, Conrad A, Morris, Shelli M, Sarthy, Jay, Cole, Bonnie L, Leary, Sarah E S, Crane, Courtney, Lieberman, Nicole A P, Mueller, Sabine, Nazarian, Javad, Gottardo, Raphael, Brusniak, Mi-Youn, Mhyre, Andrew J, Olson, James M

“…Abstract Background Diffuse midline gliomas (DMGs), including diffuse intrinsic pontine gliomas (DIPGs), have a dismal prognosis, with less than 2% surviving 5…”
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Changes to pediatric brain tumors in 2021 World Health Organization classification of tumors of the central nervous system by Oztek, Murat Alp, Noda, Sakura M., Romberg, Erin K., Cole, Bonnie L., Wright, Jason N., Ishak, Gisele E., Perez, Francisco A.

“…New tumor types are continuously being described with advances in molecular testing and genomic analysis resulting in better prognostics, new targeted therapy…”
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Sensitization of osteosarcoma to irradiation by targeting nuclear FGFR1 by Kim, Jin-Ah, Berlow, Noah E., Lathara, Melvin, Bharathy, Narendra, Martin, Leah R., Purohit, Reshma, Cleary, Megan M., Liu, Qianqian, Michalek, Joel E., Srinivasa, Ganapati, Cole, Bonnie L., Chen, Sonja D., Keller, Charles

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Imaging of pediatric pancreatic neoplasms with radiologic-histopathologic correlation by Shet, Narendra S, Cole, Bonnie L, Iyer, Ramesh S

“…The purpose of this article is to describe the imaging features of pediatric pancreatic tumors with pathologic correlation. Epithelial and nonepithelial…”
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Children with DIPG and high-grade glioma treated with temozolomide, irinotecan, and bevacizumab: the Seattle Children’s Hospital experience by Crotty, Erin E., Leary, Sarah E. S., Geyer, J. Russell, Olson, James M., Millard, Nathan E., Sato, Aimee A., Ermoian, Ralph P., Cole, Bonnie L., Lockwood, Christina M., Paulson, Vera A., Browd, Samuel R., Ellenbogen, Richard G., Hauptman, Jason S., Lee, Amy, Ojemann, Jeffrey G., Vitanza, Nicholas A.

“…Introduction Beyond focal radiation, there is no consensus standard therapy for pediatric high-grade glioma (pHGG) and outcomes remain dismal. We describe the…”
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Desmoplastic Infantile Ganglioglioma/Astrocytoma (DIG/DIA) Are Distinct Entities with Frequent BRAFV600 Mutations by Wang, Anthony C, Jones, David T W, Abecassis, Isaac Joshua, Cole, Bonnie L, Leary, Sarah E S, Lockwood, Christina M, Chavez, Lukas, Capper, David, Korshunov, Andrey, Fallah, Aria, Wang, Shelly, Ene, Chibawanye, Olson, James M, Geyer, J Russell, Holland, Eric C, Lee, Amy, Ellenbogen, Richard G, Ojemann, Jeffrey G

“…Desmoplastic infantile ganglioglioma (DIG) and desmoplastic infantile astrocytoma (DIA) are extremely rare tumors that typically arise in infancy; however,…”
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Two cases of pineal anlage tumor with molecular analysis by Scherpelz, Kathryn P., Crotty, Erin E., Paulson, Vera A., Lockwood, Christina M., Leary, Sarah E. S., Ellenbogen, Richard G., Lee, Amy, Ermoian, Ralph P., Vitanza, Nicholas A., Cole, Bonnie L.

“…Pineal anlage tumor is a rare pediatric tumor with clinical and histological features overlapping with pineoblastoma. Two patients with pineal anlage tumor, a…”
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Extramedullary Hematopoiesis in the Dura Mater During Treatment of a CNS Embryonal Tumor by Ganapathi, Shireen S., Havard, Molly E., Ferguson, Mark, Cole, Bonnie L., Millard, Nathan E., Vitanza, Nicholas A.

“…Extramedullary hematopoiesis (EMH) is hematopoiesis occurring outside of the bone marrow. It has been reported to develop in abdominal organs or lymph nodes…”
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Current Utilization of Electron Microscopy in the Pediatric Pathology Setting: A Survey by the SPP Practice Committee by Warren, Mikako, Reed, Robyn C., Prasad, Vinay, Rajaram, Veena, Roberts, Drucilla, Kreiger, Portia A., Darrisaw, Lora, Besmer, Sherri, Church, Alanna J., Keisling, Matthew, Craver, Randall D., Cole, Bonnie L., Robers, James, Lopez-Terrada, Dolores

“…Background: Electron microscopy (EM), once an important component in diagnosing pediatric diseases, has experienced a decline in its use. To assess the impact…”
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