Search Results - "Colby, Donn J"
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Initial productive and latent HIV infections originate in vivo by infection of resting T cells
Published in The Journal of clinical investigation (15-11-2023)“…Productively infected cells are generally thought to arise from HIV infection of activated CD4+ T cells, and these infected activated cells are thought to be a…”
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Feasibility, acceptability, and short-term impact of a brief sexually transmitted infection intervention targeting U.S. Military personnel and family members
Published in BMC public health (02-04-2022)“…Over the past 10 years, incidence of sexually transmitted infections (STIs) has increased to record numbers in the United States, with the most significant…”
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HIV prevalence and incidence among men who have sex with men and transgender women in Bangkok, 2014-2018: Outcomes of a consensus development initiative
Published in PloS one (21-01-2022)“…To reach its goal of ending AIDS by 2030, Thailand has adopted antiretroviral treatment as prevention and HIV pre-exposure prophylaxis for men who have sex…”
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4
Leveraging early HIV diagnosis and treatment in Thailand to conduct HIV cure research
Published in AIDS research and therapy (06-09-2019)“…Thailand has the highest prevalence of HIV among countries in Asia but has also been a pioneer in HIV prevention and treatment efforts in the region, reducing…”
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5
Mosaic vaccine-induced antibody-dependent cellular phagocytosis associated with delayed HIV-1 viral load rebound post treatment interruption
Published in Cell reports (Cambridge) (25-06-2024)“…A heterologous Ad26/MVA vaccine was given prior to an analytic treatment interruption (ATI) in people living with HIV-1 (mainly CRF01_AE) who initiated…”
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6
Field evaluation of a prototype paper-based point-of-care fingerstick transaminase test
Published in PloS one (30-09-2013)“…Monitoring for drug-induced liver injury (DILI) via serial transaminase measurements in patients on potentially hepatotoxic medications (e.g., for HIV and…”
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7
Altered Memory Circulating T Follicular Helper-B Cell Interaction in Early Acute HIV Infection
Published in PLoS pathogens (01-07-2016)“…The RV254 cohort of HIV-infected very early acute (4thG stage 1 and 2) (stage 1/2) and late acute (4thG stage 3) (stage 3) individuals was used to study T…”
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A randomized trial of vorinostat with treatment interruption after initiating antiretroviral therapy during acute HIV-1 infection
Published in Journal of Virus Eradication (01-09-2020)“…Objective and Design: A randomized, open-label pilot study in individuals treated with antiretroviral therapy (ART) since acute HIV infection (AHI) with a…”
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9
Substance use and universal access to HIV testing and treatment in sub-Saharan Africa: implications and research priorities
Published in Journal of Virus Eradication (01-11-2018)“…As universal testing and treatment for HIV, or ‘treat all’, expands across sub-Saharan Africa (SSA), substance use will likely have a negative impact on the…”
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Factors associated with HIV viral load suppression on antiretroviral therapy in Vietnam
Published in Journal of Virus Eradication (01-04-2016)“…Background: Limited data are available on HIV viral suppression rates among men and women on antiretroviral therapy (ART) and factors associated with HIV RNA…”
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Declining trend in transmitted drug resistance detected in a prospective cohort study of acute HIV infection in Bangkok, Thailand
Published in Journal of the International AIDS Society (01-01-2016)“…Introduction As availability of antiretroviral therapy expands in developing countries, the risk for transmission of drug‐resistant HIV also increases…”
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Feasibility and safety of research sigmoid colon biopsy in a cohort of Thai men who have sex with men with acute HIV-1
Published in Journal of Virus Eradication (01-01-2020)“…Background: The gut-associated lymphoid tissue (GALT) is a major reservoir of HIV-1 established early in acute HIV-1 infection (AHI). Sampling tissue from GALT…”
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Rapid HIV RNA rebound after antiretroviral treatment interruption in persons durably suppressed in Fiebig I acute HIV infection
Published in Nature medicine (01-07-2018)“…Antiretroviral therapy during the earliest stage of acute HIV infection (Fiebig I) might minimize establishment of a latent HIV reservoir and thereby…”
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Brief Report: Syphilis Incidence and Effect on Viral Load, CD4, and CD4/CD8 Ratio in a Thai Cohort of Predominantly Men Who Have Sex With Men Living With HIV
Published in Journal of acquired immune deficiency syndromes (1999) (01-02-2021)“…Syphilis has been increasing in the past years, especially among men who have sex with men (MSM). The aim of the study was to assess syphilis prevalence and…”
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Acquisition of Multidrug-Resistant Human Immunodeficiency Virus Type 1 Infection in a Patient Taking Preexposure Prophylaxis
Published in Clinical infectious diseases (31-08-2018)“…Abstract We report a case indicating that acquisition of multidrug-resistant human immunodeficiency (HIV) virus type 1 during preexposure prophylaxis with…”
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Brief Report: Group Sex and Methamphetamine Use Fuel an Explosive Epidemic of Hepatitis C Among HIV-Infected Men Who Have Sex With Men in Bangkok, Thailand
Published in Journal of acquired immune deficiency syndromes (1999) (01-08-2020)“…BACKGROUND:Increased rates of hepatitis C virus (HCV) infection among HIV-infected men who have sex with men (MSM) and who deny injecting drugs have been…”
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Response to hepatitis B vaccination among HIV-infected adults in Vietnam
Published in Journal of Virus Eradication (01-04-2016)“…Objectives: We sought to determine the rate of response to hepatitis B (HBV) vaccination among HIV-infected adults in Vietnam. Methods: We retrospectively…”
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Safety and immunogenicity of Ad26 and MVA vaccines in acutely treated HIV and effect on viral rebound after antiretroviral therapy interruption
Published in Nature medicine (01-04-2020)“…We administered Ad26, modified vaccinia Ankara vectors containing mosaic HIV-1 antigens or placebo in 26 individuals who initiated antiretroviral therapy…”
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Plasmacytoid dendritic cells sense HIV replication before detectable viremia following treatment interruption
Published in The Journal of clinical investigation (01-06-2020)“…Plasmacytoid dendritic cells (pDCs) are robust producers of IFNα and one of the first immune cells to respond to SIV infection. To elucidate responses to early…”
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Recommendations for analytical antiretroviral treatment interruptions in HIV research trials—report of a consensus meeting
Published in The lancet HIV (01-04-2019)“…Analytical antiretroviral treatment interruption (ATI) is an important feature of HIV research, seeking to achieve sustained viral suppression in the absence…”
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