Search Results - "Colbran, R."
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Evidence against dopamine D1/D2 receptor heteromers
Published in Molecular psychiatry (01-11-2015)“…Hetero-oligomers of G-protein-coupled receptors have become the subject of intense investigation, because their purported potential to manifest signaling and…”
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Quality of Life and Financial Impacts of Permanent Colostomy for Rectal Cancer
Published in Journal of Coloproctology (01-03-2024)“…Abstract Introduction Returning to work is an important cancer recovery milestone. Permanent colostomy can be required for rectal cancer treatment and can…”
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Orthogonal external ventricular drain (EVD) trajectory from burr holes sited by junior neurosurgical staff is superior to freehand placement: An in-silico model
Published in Journal of clinical neuroscience (01-12-2021)“…•Angular variation from orthogonal is associated with EVD malposition.•Modelling suggests orthogonal EVD trajectories would improve placement…”
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Targeting of calcium/calmodulin-dependent protein kinase II
Published in Biochemical journal (15-02-2004)“…Calcium/calmodulin-dependent protein kinase II (CaMKII) has diverse roles in virtually all cell types and it is regulated by a plethora of mechanisms. Local…”
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Calcium/calmodulin-dependent protein kinase II and synaptic plasticity
Published in Current opinion in neurobiology (01-06-2004)“…A prominent role for calcium/calmodulin-dependent protein kinase II (CaMKII) in regulation of excitatory synaptic transmission was proposed two decades ago…”
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Autophosphorylation-dependent targeting of calcium/ calmodulin-dependent protein kinase II by the NR2B subunit of the N-methyl- D-aspartate receptor
Published in The Journal of biological chemistry (14-08-1998)“…Activation and Thr286 autophosphorylation of calcium/calmodulindependent kinase II (CaMKII) following Ca2+ influx via N-methyl-D-aspartate (NMDA)-type…”
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Differential Inactivation of Postsynaptic Density‐Associated and Soluble Ca2+/Calmodulin‐Dependent Protein Kinase II by Protein Phosphatases 1 and 2A
Published in Journal of neurochemistry (01-05-1997)“…: Autophosphorylation of Ca2+/calmodulin‐dependent protein kinase II (CaMKII) at Thr286 generates Ca2+‐independent activity. As an initial step toward…”
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Mechanism and Regulation of Calcium/Calmodulin-dependent Protein Kinase II Targeting to the NR2B Subunit of the N-Methyl-d-aspartate Receptor
Published in The Journal of biological chemistry (04-08-2000)“…Calcium influx through the N-methyl-d-aspartate (NMDA)-type glutamate receptor and activation of calcium/calmodulin-dependent kinase II (CaMKII) are critical…”
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Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels
Published in Nature cell biology (01-03-2000)“…A dynamic positive feedback mechanism, known as 'facilitation', augments L-type calcium-ion currents (ICa) in response to increased intracellular Ca2+…”
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Inactivation of Ca2+/calmodulin-dependent protein kinase II by basal autophosphorylation
Published in The Journal of biological chemistry (05-04-1993)“…Incubation of either purified rat forebrain Ca2+/calmodulin-dependent protein kinase II (CaMKII) or the purified recombinant, baculovirus-expressed mouse alpha…”
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CaMKIIα enhances the desensitization of NR2B-containing NMDA receptors by an autophosphorylation-dependent mechanism
Published in Molecular and cellular neuroscience (01-05-2005)“…Long-term potentiation or depression of synaptic function often requires Ca 2+ influx via NMDA-type glutamate receptors (NMDARs) and changes in the…”
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Translocation of Autophosphorylated Calcium/Calmodulin-dependent Protein Kinase II to the Postsynaptic Density
Published in The Journal of biological chemistry (23-05-1997)“…Calcium/calmodulin-dependent protein kinase II (CaMKII) undergoes calcium-dependent autophosphorylation, generating a calcium-independent form that may serve…”
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Calcium/calmodulin-dependent protein kinase II. Characterization of distinct calmodulin binding and inhibitory domains
Published in The Journal of biological chemistry (25-05-1988)“…Regulatory domains of the multifunctional Ca2+/calmodulin-dependent protein kinase II were investigated utilizing synthetic peptides. These peptides were…”
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Targeting Protein Phosphatase 1 (PP1) to the Actin Cytoskeleton: the Neurabin I/PP1 Complex Regulates Cell Morphology
Published in Molecular and Cellular Biology (01-07-2002)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Is Persistent Activity of Calcium/Calmodulin-Dependent Kinase Required for the Maintenance of LTP?
Published in Journal of neurophysiology (01-04-2001)“… 1 Volen Center for Complex Systems, Brandeis University, Waltham, Massachusetts 02454; and 2 Department of Molecular Physiology and Biophysics and Center…”
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Calcium/calmodulin-independent autophosphorylation sites of calcium/calmodulin-dependent protein kinase II. Studies on the effect of phosphorylation of threonine 305/306 and serine 314 on calmodulin binding using synthetic peptides
Published in The Journal of biological chemistry (05-07-1990)“…Two synthetic peptides containing the previously identified calmodulin (CaM)-binding domain of Ca2+/CaM-dependent protein kinase II (CaM-kinase II) (residues…”
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Calcium/calmodulin-dependent protein kinase II
Published in Biochemical journal (01-03-1989)“…CaM-kinase Ii is a member of a family of Ca super(2+)/calmodulin-regulated protein kinases which also induces Ca super(2+)/calmodulin-dependent protein kinases…”
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CaM kinase augments cardiac L-type Ca2+ current: a cellular mechanism for long Q-T arrhythmias
Published in The American journal of physiology (01-06-1999)“…Early afterdepolarizations (EAD) caused by L-type Ca2+ current (ICa, L) are thought to initiate long Q-T arrhythmias, but the role of intracellular Ca2+ in…”
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Brain protein phosphatase 2A: Developmental regulation and distinct cellular and subcellular localization by B subunits
Published in Journal of comparative neurology (1911) (23-03-1998)“…Protein phosphatase 2A (PP2A) is a heterotrimeric enzyme consisting of a catalytic subunit (C), a structural subunit (A), and a variable regulatory subunit…”
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