Search Results - "Colbert, Sarah M.C."

The addiction risk factor: A unitary genetic vulnerability characterizes substance use disorders and their associations with common correlates by Hatoum, Alexander S, Johnson, Emma C, Colbert, Sarah M C, Polimanti, Renato, Zhou, Hang, Walters, Raymond K, Gelernter, Joel, Edenberg, Howard J, Bogdan, Ryan, Agrawal, Arpana

“…Substance use disorders commonly co-occur with one another and with other psychiatric disorders. They share common features including high impulsivity,…”
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Commentary on Lannoy et al.: The continued value of within‐family designs in addiction and psychiatric research by Colbert, Sarah M. C., Johnson, Emma C.

“…Family-based designs continue to be valuable for establishing evidence of causal relationships in studies of substance use disorders and other mental health…”
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Association of Mental Health Burden With Prenatal Cannabis Exposure From Childhood to Early Adolescence: Longitudinal Findings From the Adolescent Brain Cognitive Development (ABCD) Study by Baranger, David A A, Paul, Sarah E, Colbert, Sarah M C, Karcher, Nicole R, Johnson, Emma C, Hatoum, Alexander S, Bogdan, Ryan

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Declining autozygosity over time: An exploration in over 1 million individuals from three diverse cohorts by Colbert, Sarah M.C., Wendt, Frank R., Pathak, Gita A., Helmer, Drew A., Hauser, Elizabeth R., Keller, Matthew C., Polimanti, Renato, Johnson, Emma C.

“…Previous studies have hypothesized that autozygosity is decreasing over generational time. However, these studies were limited to relatively small samples…”
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Exploring the genetic overlap of suicide‐related behaviors and substance use disorders by Colbert, Sarah M. C., Hatoum, Alexander S., Shabalin, Andrey, Li, Qingqin S., Coon, Hilary, Nelson, Elliot C., Agrawal, Arpana, Docherty, Anna R., Johnson, Emma C.

“…Suicide‐related behaviors are heterogeneous and transdiagnostic, and may demonstrate varying levels of genetic overlap with different substance use disorders…”
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Associations Between Cannabis Use, Polygenic Liability for Schizophrenia, and Cannabis-related Experiences in a Sample of Cannabis Users by Johnson, Emma C, Colbert, Sarah M C, Jeffries, Paul W, Tillman, Rebecca, Bigdeli, Tim B, Karcher, Nicole R, Chan, Grace, Kuperman, Samuel, Meyers, Jacquelyn L, Nurnberger, John I, Plawecki, Martin H, Degenhardt, Louisa, Martin, Nicholas G, Kamarajan, Chella, Schuckit, Marc A, Murray, Robin M, Dick, Danielle M, Edenberg, Howard J, D’Souza, Deepak Cyril, Di Forti, Marta, Porjesz, Bernice, Nelson, Elliot C, Agrawal, Arpana

“…Abstract Background and Hypothesis Risk for cannabis use and schizophrenia is influenced in part by genetic factors, and there is evidence that genetic risk…”
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Novel characterization of the multivariate genetic architecture of internalizing psychopathology and alcohol use by Colbert, Sarah M. C., Funkhouser, Scott A., Johnson, Emma C., Morrison, Claire L., Hoeffer, Charles A., Friedman, Naomi P., Ehringer, Marissa A., Evans, Luke M.

“…Genetic correlations suggest that the genetic relationship of alcohol use with internalizing psychopathology depends on the measure of alcohol use. Problematic…”
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Characterizing Alcohol Expectancies in the ABCD Study: Associations with Sociodemographic Factors, the Immediate Social Environment, and Genetic Propensities by Johnson, Emma C., Paul, Sarah E., Baranger, David A. A., Hatoum, Alexander S., Colbert, Sarah M. C., Lin, Shuyu, Wolff, Rachel, Gorelik, Aaron J., Hansen, Isabella, Karcher, Nicole R., Bogdan, Ryan, Agrawal, Arpana

“…Alcohol expectancies (AEs) are associated with likelihood of alcohol initiation and subsequent alcohol use disorders. It is unclear whether genetic…”
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A Phenome-Wide Association Study (PheWAS) of Late Onset Alzheimer Disease Genetic Risk in Children of European Ancestry at Middle Childhood: Results from the ABCD Study by Gorelik, Aaron J., Paul, Sarah E., Karcher, Nicole R., Johnson, Emma C., Nagella, Isha, Blaydon, Lauren, Modi, Hailey, Hansen, Isabella S., Colbert, Sarah M. C., Baranger, David A. A., Norton, Sara A., Spears, Isaiah, Gordon, Brian, Zhang, Wei, Hill, Patrick L., Oltmanns, Thomas F., Bijsterbosch, Janine D., Agrawal, Arpana, Hatoum, Alexander S., Bogdan, Ryan

“…Genetic risk for Late Onset Alzheimer Disease (AD) has been associated with lower cognition and smaller hippocampal volume in healthy young adults. However,…”
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Genetic Liability to Cannabis Use Disorder and COVID-19 Hospitalization by Hatoum, Alexander S., Morrison, Claire L., Colbert, Sarah M.C., Winiger, Evan A., Johnson, Emma C., Agrawal, Arpana, Bogdan, Ryan

“…Vulnerability to COVID-19 hospitalization has been linked to behavioral risk factors, including combustible psychoactive substance use (e.g., tobacco smoking)…”
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Polygenic Contributions to Suicidal Thoughts and Behaviors in a Sample Ascertained for Alcohol Use Disorders by Colbert, Sarah M.C., Mullins, Niamh, Chan, Grace, Meyers, Jacquelyn L., Schulman, Jessica, Kuperman, Samuel, Lai, Dongbing, Nurnberger, John, Plawecki, Martin H., Kamarajan, Chella, Anokhin, Andrey P., Bucholz, Kathleen K., Hesselbrock, Victor, Edenberg, Howard J., Kramer, John, Dick, Danielle M., Porjesz, Bernice, Agrawal, Arpana, Johnson, Emma C.

“…Introduction: Suicidal thoughts and behaviors have partially distinct genetic etiologies. Methods: We used PRS-CS to create polygenic risk scores (PRSs) from…”
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Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders by Hatoum, Alexander S, Colbert, Sarah M C, Johnson, Emma C, Huggett, Spencer B, Deak, Joseph D, Pathak, Gita, Jennings, Mariela V, Paul, Sarah E, Karcher, Nicole R, Hansen, Isabella, Baranger, David A A, Edwards, Alexis, Grotzinger, Andrew, Tucker-Drob, Elliot M, Kranzler, Henry R, Davis, Lea K, Sanchez-Roige, Sandra, Polimanti, Renato, Gelernter, Joel, Edenberg, Howard J, Bogdan, Ryan, Agrawal, Arpana

“…Genetic liability to substance use disorders can be parsed into loci that confer general or substance-specific addiction risk. We report a multivariate…”
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