Search Results - "Colbert, Lauren E"

Microbiome factors in HPV-driven carcinogenesis and cancers by Lin, Daniel, Kouzy, Ramez, Abi Jaoude, Joseph, Noticewala, Sonal S, Delgado Medrano, Andrea Y, Klopp, Ann H, Taniguchi, Cullen M, Colbert, Lauren E

“…About the Authors: Daniel Lin Affiliation: Department of Radiation Oncology, Division of Radiation Oncology, University of Texas MD Anderson Cancer Center,…”
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Gut microbial diversity and genus-level differences identified in cervical cancer patients versus healthy controls by Sims, Travis T, Colbert, Lauren E, Zheng, Jiali, Delgado Medrano, Andrea Y, Hoffman, Kristi L, Ramondetta, Lois, Jazaeri, Amir, Jhingran, Anuja, Schmeler, Kathleen M, Daniel, Carrie R, Klopp, Ann

“…AbstractObjectivesThe aim of this study was to characterize variation in the gut microbiome of women with locally advanced cervical cancer and compare it to…”
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Immune environment and antigen specificity of the T cell receptor repertoire of malignant ascites in ovarian cancer by Yoshida-Court, Kyoko, Karpinets, Tatiana V, Mitra, Aparna, Solley, Travis N, Dorta-Estremera, Stephanie, Sims, Travis T, Delgado Medrano, Andrea Y, El Alam, Molly B, Ahmed-Kaddar, Mustapha, Lynn, Erica J, Sastry, K Jagannadha, Zhang, Jianhua, Futreal, Andrew, Nick, Alpa, Lu, Karen, Colbert, Lauren E, Klopp, Ann H

“…We evaluated the association of disease outcome with T cell immune-related characteristics and T cell receptor (TCR) repertoire in malignant ascites from…”
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Kinetics of Intratumoral Immune Cell Activation During Chemoradiation for Cervical Cancer by Dorta-Estremera, Stephanie, Colbert, Lauren E., Nookala, Sita S., Yanamandra, Ananta V., Yang, Guojun, Delgado, Andrea, Mikkelson, Megan, Eifel, Patricia, Jhingran, Anuja, Lilie, Lin L., Welsh, James, Schmeler, Kathleen, Sastry, Jagannadha K., Klopp, Ann

“…Radiation therapy has direct cytotoxic effects on tumor-infiltrating lymphocytes, but it also has immune stimulatory effects that increase immune cell…”
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Correction: Immune environment and antigen specificity of the T cell receptor repertoire of malignant ascites in ovarian cancer by Yoshida-Court, Kyoko, Karpinets, Tatiana V, Mitra, Aparna, Solley, Travis N, Dorta-Estremera, Stephanie, Sims, Travis T, Delgado Medrano, Andrea Y, Alam, Molly B. El, Ahmed-Kaddar, Mustapha, Lynn, Erica J, Sastry, K. Jagannadha, Zhang, Jianhua, Futreal, Andrew, Nick, Alpa, Lu, Karen, Colbert, Lauren E, Klopp, Ann H

“…[This corrects the article DOI: 10.1371/journal.pone.0279590.].[This corrects the article DOI: 10.1371/journal.pone.0279590.]…”
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Intratumoral microbiome of adenoid cystic carcinomas and comparison with other head and neck cancers by Karpinets, Tatiana V., Mitani, Yoshitsugu, Chang, Chia-Chi, Wu, Xiaogang, Song, Xingzhi, Flores, Ivonne I., McDaniel, Lauren K., Hoballah, Yasmine M., Veguilla, Fabiana J., Ferrarotto, Renata, Colbert, Lauren E., Ajami, Nadim J., Jenq, Robert R., Zhang, Jianhua, Futreal, Andrew P., El-Naggar, Adel K.

“…Adenoid cystic carcinoma (ACC) is a rare, usually slow-growing yet aggressive head and neck malignancy. Despite its clinical significance, our understanding of…”
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Feasibility of a novel non-invasive swab technique for serial whole-exome sequencing of cervical tumors during chemoradiation therapy by Bronk, Julianna K, Kapadia, Chiraag, Wu, Xiaogang, Chapman, Bhavana V, Wang, Rui, Karpinets, Tatiana V, Song, Xingzhi, Futreal, Andrew M, Zhang, Jianhua, Klopp, Ann H, Colbert, Lauren E

“…Background Clinically relevant genetic predictors of radiation response for cervical cancer are understudied due to the morbidity of repeat invasive biopsies…”
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A prospective study of the adaptive changes in the gut microbiome during standard-of-care chemoradiotherapy for gynecologic cancers by El Alam, Molly B, Sims, Travis T, Kouzy, Ramez, Biegert, Greyson W G, Jaoude, Joseph A B I, Karpinets, Tatiana V, Yoshida-Court, Kyoko, Wu, Xiaogang, Delgado-Medrano, Andrea Y, Mezzari, Melissa P, Ajami, Nadim J, Solley, Travis, Ahmed-Kaddar, Mustapha, Lin, Lilie L, Ramondetta, Lois, Jazaeri, Amir, Jhingran, Anuja, Eifel, Patricia J, Schmeler, Kathleen M, Wargo, Jennifer, Klopp, Ann H, Colbert, Lauren E

“…A diverse and abundant gut microbiome can improve cancer patients' treatment response; however, the effect of pelvic chemoradiotherapy (CRT) on gut diversity…”
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HPV-related anal cancer is associated with changes in the anorectal microbiome during cancer development by Elnaggar, Jacob H, Huynh, Victoria O, Lin, Daniel, Hillman, R Tyler, Abana, Chike O, El Alam, Molly B, Tomasic, Katarina C, Karpinets, Tatiana V, Kouzy, Ramez, Phan, Jae L, Wargo, Jennifer, Holliday, Emma B, Das, Prajnan, Mezzari, Melissa P, Ajami, Nadim J, Lynn, Erica J, Minsky, Bruce D, Morris, Van K, Milbourne, Andrea, Messick, Craig A, Klopp, Ann H, Futreal, P Andrew, Taniguchi, Cullen M, Schmeler, Kathleen M, Colbert, Lauren E

“…Squamous cell carcinoma of the anus (SCCA) is a rare gastrointestinal cancer. Factors associated with progression of HPV infection to anal dysplasia and cancer…”
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Gut microbiome diversity is an independent predictor of survival in cervical cancer patients receiving chemoradiation by Sims, Travis T., El Alam, Molly B., Karpinets, Tatiana V., Dorta-Estremera, Stephanie, Hegde, Venkatesh L., Nookala, Sita, Yoshida-Court, Kyoko, Wu, Xiaogang, Biegert, Greyson W. G., Delgado Medrano, Andrea Y., Solley, Travis, Ahmed-Kaddar, Mustapha, Chapman, Bhavana V., Sastry, K. Jagannadha, Mezzari, Melissa P., Petrosino, Joseph F., Lin, Lilie L., Ramondetta, Lois, Jhingran, Anuja, Schmeler, Kathleen M., Ajami, Nadim J., Wargo, Jennifer, Colbert, Lauren E., Klopp, Ann H.

“…Diversity of the gut microbiome is associated with higher response rates for cancer patients receiving immunotherapy but has not been investigated in patients…”
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Metagenomes of rectal swabs in larger, advanced stage cervical cancers have enhanced mucus degrading functionalities and distinct taxonomic structure by Karpinets, Tatiana V, Wu, Xiaogang, Solley, Travis, El Alam, Molly B, Sims, Travis T, Yoshida-Court, Kyoko, Lynn, Erica, Ahmed-Kaddar, Mustapha, Biegert, Greyson, Yue, Jingyan, Song, Xingzhi, Sun, Huandong, Petrosino, Joseph F, Mezzari, Melissa P, Okhuysen, Pablo, Eifel, Patricia J, Jhingran, Anuja, Lin, Lilie L, Schmeler, Kathleen M, Ramondetta, Lois, Ajami, Nadim, Jenq, Robert R, Futreal, Andrew, Zhang, Jianhua, Klopp, Ann H, Colbert, Lauren E

“…Gut microbiome community composition differs between cervical cancer (CC) patients and healthy controls, and increased gut diversity is associated with…”
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Chemoradiation therapy sequencing for resected pancreatic adenocarcinoma in the National Cancer Data Base by Colbert, Lauren E., Hall, William A., Nickleach, Dana, Switchenko, Jeffrey, Kooby, David A., Liu, Yuan, Gillespie, Theresa, Lipscomb, Joseph, Kauh, John, Landry, Jerome C.

“…BACKGROUND Pancreatic adenocarcinoma (PAC) has low overall survival (OS) rates and high recurrence rates following surgical resection. The role for…”
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Proton beam radiation as salvage therapy for bilateral colorectal liver metastases not amenable to second-stage hepatectomy by Colbert, Lauren E., MD, MSCR, Cloyd, Jordan M., MD, Koay, Eugene J., MD, PhD, Crane, Christopher H., MD, Vauthey, Jean-Nicolas, MD

“…Background Bilobar colorectal liver metastases (CRLM), are now aggressively managed in a multidisciplinary fashion with a two-stage hepatectomy; however, up to…”
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Cervicovaginal Microbiota Profiles in Precancerous Lesions and Cervical Cancer among Ethiopian Women by Teka, Brhanu, Yoshida-Court, Kyoko, Firdawoke, Ededia, Chanyalew, Zewditu, Gizaw, Muluken, Addissie, Adamu, Mihret, Adane, Colbert, Lauren E, Napravnik, Tatiana Cisneros, El Alam, Molly B, Lynn, Erica J, Mezzari, Melissa, Anuja, Jhingran, Kantelhardt, Eva Johanna, Kaufmann, Andreas M, Klopp, Ann H, Abebe, Tamrat

“…Although high-risk human papillomavirus infection is a well-established risk factor for cervical cancer, other co-factors within the local microenvironment may…”
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Protocol for culturing patient-derived organoids of cervical cancer by Wang, Rui, Harris, Timothy, Negrón-Figueroa, Dalissa, Lo, David, Judge, Allison, Walters, D’Shaunique, Jiang, Bo, Colbert, Lauren E.

“…Herein, we present a protocol for culturing patient-derived organoids (PDOs) of cervical cancer that includes workflows for tumor biopsy/resection tissue and…”
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The Role of the Cervicovaginal and Gut Microbiome in Cervical Intraepithelial Neoplasia and Cervical Cancer by Sims, Travis T, Colbert, Lauren E, Klopp, Ann H

“…The microbiome, which refers to the microbiota within a host and their collective genomes, has recently been demonstrated to play a critical role in cancer…”
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Discharge to Subacute Rehabilitation Facilities Does Not Benefit Patients Hospitalized With Progressive Gastrointestinal Cancer by Desai, Anjali V., MD, Epstein, Andrew S., MD, Colbert, Lauren E., MD, MSCR, Saltz, Leonard B., MD

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High Nuclear Hypoxia-Inducible Factor 1 Alpha Expression Is a Predictor of Distant Recurrence in Patients With Resected Pancreatic Adenocarcinoma by Colbert, Lauren E., MD, MSCR, Fisher, Sarah B., MD, MSCR, Balci, Serdar, MD, Saka, Burcu, MD, Chen, Zhengjia, PhD, Kim, Sungjin, MS, El-Rayes, Bassel F., MD, Adsay, N. Volkan, MD, Maithel, Shishir K., MD, Landry, Jerome C., MD, MBA, Curran, Walter J., MD

“…Purpose To evaluate nuclear hypoxia-inducible factor 1α (HIF-1α) expression as a prognostic factor for distant recurrence (DR) and local recurrence (LR) after…”
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Circulating neutrophils and tumor-associated myeloid cells function as a powerful biomarker for response to chemoradiation in locally advanced cervical cancer by Gjyshi, Olsi, Grippin, Adam, Andring, Lauren, Jhingran, Anuja, Lin, Lilie L., Bronk, Julianna, Eifel, Patricia J., Joyner, Melissa M., Sastry, Jagannadha K., Yoshida-Court, Kyoko, Solley, Travis N., Napravnik, Tatiana Cisneros, O'Hara, Madison P., Hegde, Venkatesh L, Colbert, Lauren E., Klopp, Ann H

“…•On-treatment mean neutrophil count predicts disease related treatment outcomes for patients with locally advanced cervical cancer.•Neutrophil counts in tumors…”
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Dose escalation for locally advanced pancreatic cancer: How high can we go? by Colbert, Lauren E., MD, Rebueno, Neal, CMD, Moningi, Shalini, MD, Beddar, Sam, PhD, Sawakuchi, Gabriel O., PhD, Herman, Joseph M., MD, Koong, Albert C., MD, PhD, Das, Prajnan, MD, Holliday, Emma B., MD, Koay, Eugene J., MD, PhD, Taniguchi, Cullen M., MD, PhD

“…Abstract Purpose There are limited treatment options for locally advanced, unresectable pancreatic cancer (LAPC) and no likelihood of cure without surgery…”
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