Search Results - "Colbert, C."

Neural Crest Cells Retain Multipotential Characteristics in the Developing Valves and Label the Cardiac Conduction System by Nakamura, Tomoki, Colbert, Melissa C, Robbins, Jeffrey

“…Multipotent neural crest cells (NCCs) are a major extracardiac component of cardiovascular development. Although recognized as contributing cells to the…”
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Differential activation of airway eosinophils induces IL‐13‐mediated allergic Th2 pulmonary responses in mice by Jacobsen, E. A., Doyle, A. D., Colbert, D. C., Zellner, K. R., Protheroe, C. A., LeSuer, W. E., Lee, N. A., Lee, J. J.

“…Background Eosinophils are hallmark cells of allergic Th2 respiratory inflammation. However, the relative importance of eosinophil activation and the induction…”
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Human versus mouse eosinophils: “That which we call an eosinophil, by any other name would stain as red” by Lee, James J., PhD, Jacobsen, Elizabeth A., PhD, Ochkur, Sergei I., PhD, McGarry, Michael P., PhD, Condjella, Rachel M., PhD, Doyle, Alfred D., BS, Luo, Huijun, PhD, Zellner, Katie R., BS, Protheroe, Cheryl A., BA, Willetts, Lian, BS, LeSuer, William E., BS, Colbert, Dana C., MS, Helmers, Richard A., MD, Lacy, Paige, PhD, Moqbel, Redwan, PhD, FRCPath, Lee, Nancy A., PhD

“…The respective life histories of human subjects and mice are well defined and describe a unique story of evolutionary conservation extending from sequence…”
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Non-Ketotic Hyperglycemic Hemichorea-Hemiballismus in the Setting of Antipsychotics and Methamphetamine by Nelson, Colbert C, Ohnoutka, Cole, Ulen, Michael

“…The management of common chronic conditions presenting in uncommon ways is an important facet of medical education and patient care. We report a 54-year-old…”
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Fatty acid synthase is a metabolic oncogene targetable in malignant peripheral nerve sheath tumors by Patel, Ami V, Johansson, Gunnar, Colbert, Melissa C, Dasgupta, Biplab, Ratner, Nancy

“…Malignant peripheral nerve sheath tumors (MPNSTs) are soft tissue sarcomas with minimal therapeutic opportunities. We observed that lipid droplets (LDs)…”
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Protein tyrosine phosphatase activity in the neural crest is essential for normal heart and skull development by Nakamura, Tomoki, Gulick, James, Colbert, Melissa C, Robbins, Jeffrey

“…Mutations within the protein tyrosine phosphatase, SHP2, which is encoded by PTPN11, cause a significant proportion of Noonan syndrome (NS) cases, typically…”
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Role of ERK1/2 signaling in congenital valve malformations in Noonan syndrome by Krenz, Maike, Gulick, James, Osinska, Hanna E, Colbert, Melissa C, Molkentin, Jeffery D, Robbins, Jeffrey

“…Noonan syndrome (NS) is the most common nonchromosomal genetic disorder associated with cardiovascular malformations. The most prominent cardiac defects in NS…”
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Prevention of Cardiac Hypertrophy in Mice by Calcineurin Inhibition by Sussman, Mark A., Lim, Hae W., Gude, Natalie, Taigen, Tyler, Olson, Eric N., Robbins, Jeffrey, Colbert, Melissa C., Gualberto, Antonio, Wieczorek, David F., Molkentin, Jeffery D.

“…Hypertrophic cardiomyopathy (HCM) is an inherited form of heart disease that affects 1 in 500 individuals. Here it is shown that calcineurin, a…”
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Mitochondrial death protein Nix is induced in cardiac hypertrophy and triggers apoptotic cardiomyopathy by Dorn, Gerald W, Yussman, Martin G, Toyokawa, Tsuyoshi, Odley, Amy, Lynch, Roy A, Wu, Guangyu, Colbert, Melissa C, Aronow, Bruce J, Lorenz, John N

“…Loss of cardiomyocytes through programmed cell death is a key event in the development of heart failure, but the inciting molecular mechanisms are largely…”
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K + channel regulation of signal propagation in dendrites of hippocampal pyramidal neurons by Johnston, Daniel, Hoffman, Dax A, Magee, Jeffrey C, Colbert, Costa M

“…Pyramidal neurons receive tens of thousands of synaptic inputs on their dendrites. The dendrites dynamically alter the strengths of these synapses and…”
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The addiction risk factor: A unitary genetic vulnerability characterizes substance use disorders and their associations with common correlates by Hatoum, Alexander S, Johnson, Emma C, Colbert, Sarah M C, Polimanti, Renato, Zhou, Hang, Walters, Raymond K, Gelernter, Joel, Edenberg, Howard J, Bogdan, Ryan, Agrawal, Arpana

“…Substance use disorders commonly co-occur with one another and with other psychiatric disorders. They share common features including high impulsivity,…”
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A Causative Relationship Exists Between Eosinophils and the Development of Allergic Pulmonary Pathologies in the Mouse by Shen, HuaHao H, Ochkur, Sergei I, McGarry, Michael P, Crosby, Jeffrey R, Hines, Edie M, Borchers, Michael T, Wang, Huiying, Biechelle, Travis L, O'Neill, Katie R, Ansay, Tracy L, Colbert, Dana C, Cormier, Stephania A, Justice, J. Paul, Lee, Nancy. A, Lee, James J

“…Asthma and mouse models of allergic respiratory inflammation are invariably associated with a pulmonary eosinophilia; however, this association has remained…”
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Nestin-CreER Mice Reveal DNA Synthesis by Nonapoptotic Neurons following Cerebral Ischemia–Hypoxia by Burns, Kevin A., Ayoub, Albert E., Breunig, Joshua J., Adhami, Faisal, Weng, Wei-Lan, Colbert, Melissa C., Rakic, Pasko, Kuan, Chia-Yi

“…The standard method of detecting neurogenesis uses bromodeoxyuridine (BrdU) to label DNA synthesis followed by double labeling with neuronal markers. However,…”
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Evidence for a strong sulfur-aromatic interaction derived from crystallographic data by Zauhar, R. J., Colbert, C. L., Morgan, R. S., Welsh, W. J.

“…We have uncovered new evidence for a significant interaction between divalent sulfur atoms and aromatic rings. Our study involves a statistical analysis of…”
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Association of Mental Health Burden With Prenatal Cannabis Exposure From Childhood to Early Adolescence: Longitudinal Findings From the Adolescent Brain Cognitive Development (ABCD) Study by Baranger, David A A, Paul, Sarah E, Colbert, Sarah M C, Karcher, Nicole R, Johnson, Emma C, Hatoum, Alexander S, Bogdan, Ryan

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Ion channel properties underlying axonal action potential initiation in pyramidal neurons by Colbert, C M, Pan, E

“…A high density of Na super(+) channels in the axon hillock, or initial segment, is believed to determine the threshold for action potential initiation in…”
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Molecular identity of olfactory bulb interneurons: transcriptional codes of periglomerular neuron subtypes by Allen, 2nd, Zegary J, Waclaw, Ronald R, Colbert, Melissa C, Campbell, Kenneth

“…Interneurons in the glomerular layer (GL) of the olfactory bulb represent a diverse set of cells, which can be identified by distinct expression of different…”
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A circuit within a circuit? by Colbert, C. M.

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Active properties of neuronal dendrites by JOHNSTON, D, MAGEE, J. C, COLBERT, C. M, CHRISTIE, B. R

“…Dendrites of neurons in the central nervous system are the principal sites for excitatory synaptic input. Although little is known about their function, two…”
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Prothrombin Deficiency Results in Embryonic and Neonatal Lethality in Mice by Sun, William Y., Witte, David P., Degen, Jay L., Colbert, Melissa C., Burkart, Melissa C., Holmback, Kenn, Xiao, Qing, Bugge, Thomas H., Sandra J. F. Degen

“…The conversion of prothrombin (FII) to the serine protease, thrombin (FIIa), is a key step in the coagulation cascade because FIIa triggers platelet…”
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