Search Results - "Colapicchioni, V"
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The biomolecular corona of nanoparticles in circulating biological media
Published in Nanoscale (01-01-2015)“…When nanoparticles come into contact with biological media, they are covered by a biomolecular 'corona', which confers a new identity to the particles. In all…”
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Mechanistic evaluation of the transfection barriers involved in lipid-mediated gene delivery: Interplay between nanostructure and composition
Published in Biochimica et biophysica acta (01-03-2014)“…Here we present a quantitative mechanism-based investigation aimed at comparing the cell uptake, intracellular trafficking, endosomal escape and final fate of…”
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In vivo protein corona patterns of lipid nanoparticles
Published in RSC advances (2017)“…In physiological environments ( e.g. the blood), nanoparticles (NPs) are surrounded by a layer of biomolecules referred to as a ‘protein corona’ (PC). The most…”
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Mechanistic Understanding of Gene Delivery Mediated by Highly Efficient Multicomponent Envelope-Type Nanoparticle Systems
Published in Molecular pharmaceutics (02-12-2013)“…We packaged condensed DNA/protamine particles in multicomponent envelope-type nanoparticle systems (MENS) combining different molar fractions of the cationic…”
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A proteomics-based methodology to investigate the protein corona effect for targeted drug delivery
Published in Molecular bioSystems (01-11-2014)“…Here we introduce a proteomics methodology based on nanoliquid-chromatography tandem mass spectrometry (nanoLC/MS-MS) to investigate the "protein corona effect…”
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In vivo protein corona patterns of lipid nanoparticlesElectronic supplementary information (ESI) available: Fig. S1. Size and zeta-potential distributions of bare liposomes. Table S1. The average size of liposomal AmBisome®. Fig. S2. Proteins associated with AmBisome® liposomes after in vitro and in vivo incubation. Fig. S3. Morphology and morphometric features of AmBisome® liposomes following in vitro and in vivo incubation. See DOI: 10.1039/c6ra25493d
Published 04-01-2017“…In physiological environments ( e.g. the blood), nanoparticles (NPs) are surrounded by a layer of biomolecules referred to as a 'protein corona' (PC). The most…”
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