Search Results - "Colak, Selcuk"

Cancer stem cells – important players in tumor therapy resistance by Colak, Selcuk, Medema, Jan P.

“…Resistance to tumor therapy is an unsolved problem in cancer treatment. A plethora of studies have attempted to explain this phenomenon and many mechanisms of…”
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Development of a Neural Network Algorithm for Estimating the Makespan in Jobshop Production Scheduling by Yildiz, Incilay, Saygin, Abdulvahap, Colak, Selcuk, Abut, Fatih

“…Since production scheduling is considered a short-term plan for future production planning, the advantages of effective scheduling and control and their…”
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Mutations in the Ras-Raf Axis Underlie the Prognostic Value of CD133 in Colorectal Cancer by KEMPER, Kristel, VERSLOOT, Miranda, MEDEMA, Jan Paul, CAMERON, Katherine, COLAK, Selçuk, DE SOUSA E MELO, Felipe, DE JONG, Joan H, BLEACKLEY, Joanne, VERMEULEN, Louis, VERSTEEG, Rogier, KOSTER, Jan

“…High expression of cancer stem cell (CSC) marker CD133 has been used as a predictor for prognosis in colorectal cancer (CRC), suggesting that enumeration of…”
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Methylation of Cancer-Stem-Cell-Associated Wnt Target Genes Predicts Poor Prognosis in Colorectal Cancer Patients by de Sousa E Melo, Felipe, Colak, Selcuk, Buikhuisen, Joyce, Koster, Jan, Cameron, Kate, de Jong, Joan H., Tuynman, Jurriaan B., Prasetyanti, Pramudita R., Fessler, Evelyn, van den Bergh, Saskia P., Rodermond, Hans, Dekker, Evelien, van der Loos, Chris M., Pals, Steven T., van de Vijver, Marc J., Versteeg, Rogier, Richel, Dick J., Vermeulen, Louis, Medema, Jan Paul

“…Gene signatures derived from cancer stem cells (CSCs) predict tumor recurrence for many forms of cancer. Here, we derived a gene signature for colorectal CSCs…”
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Bcl-2 is a critical mediator of intestinal transformation by van der Heijden, Maartje, Zimberlin, Cheryl D., Nicholson, Anna M., Colak, Selcuk, Kemp, Richard, Meijer, Sybren L., Medema, Jan Paul, Greten, Florian R., Jansen, Marnix, Winton, Douglas J., Vermeulen, Louis

“…Intestinal tumour formation is generally thought to occur following mutational events in the stem cell pool. However, active NF-κB signalling additionally…”
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Targeting colorectal cancer stem cells with inducible caspase-9 by Kemper, Kristel, Rodermond, Hans, Colak, Selçuk, Grandela, Catarina, Medema, Jan Paul

“…Colorectal cancer stem cells (CSCs) drive tumor growth and are suggested to initiate distant metastases. Moreover, colon CSCs are reportedly more resistant to…”
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ER-Stress-Induced Differentiation Sensitizes Colon Cancer Stem Cells to Chemotherapy by Wielenga, Mattheus C.B., Colak, Selcuk, Heijmans, Jarom, van Lidth de Jeude, Jooske F., Rodermond, Hans M., Paton, James C., Paton, Adrienne W., Vermeulen, Louis, Medema, Jan Paul, van den Brink, Gijs R.

“…Colon cancer stem cells (colon-CSCs) are more resistant to conventional chemotherapy than differentiated cancer cells. This subset of therapy refractory cells…”
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Performance analysis of a university hospital blood laboratory via discrete event simulation by Kadı, Deniz, Kuvvetli, Yusuf, Çolak, Selçuk

“…Due to its simplicity and efficiency, blood testing has become a crucial step in the diagnosis of a variety of diseases. In this study, a university hospital…”
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Targeting TGF-β Signaling in Cancer by Colak, Selcuk, Ten Dijke, Peter

“…The transforming growth factor (TGF)-β signaling pathway is deregulated in many diseases, including cancer. In healthy cells and early-stage cancer cells, this…”
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The cytotoxic protease granzyme M is expressed by lymphocytes of both the innate and adaptive immune system by de Koning, Pieter J.A., Tesselaar, Kiki, Bovenschen, Niels, Çolak, Selçuk, Quadir, Razi, Volman, Thomas J.H., Kummer, J. Alain

“…The cytotoxic serine protease granzyme M (GrM) is one of the five human granzymes, which are mainly expressed by cytotoxic T lymphocytes and/or NK cells. Upon…”
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A Neurogenetic approach for the resource-constrained project scheduling problem by Agarwal, Anurag, Colak, Selcuk, Erenguc, Selcuk

“…A variety of metaheuristic approaches have emerged in recent years for solving the resource-constrained project scheduling problem (RCPSP), a well-known…”
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Design, validation and performance of aspartate aminotransferase- and lactate dehydrogenase-reporting algorithms for haemolysed specimens including correction within quality specifications by Colak, Selcuk, Tasdemir, Onur, van der Schaaf, Marianne, Opdam, Frans, van den Noort, Vincent, van den Broek, Daan, van Rossum, Huub H

“…haemolysis is a major operational challenge for medical laboratories. A new experimental design was used to investigate under what conditions algorithms could…”
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A Neurogenetic approach for the resource-constrained project scheduling problem : Project management and scheduling by AGARWAL, Anurag, COLAK, Selcuk, ERENGUC, Selcuk

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Differential Expression of DNA Repair Genes in Prognostically-Favorable versus Unfavorable Uveal Melanoma by Dogrusöz, Mehmet, Ruschel Trasel, Andrea, Cao, Jinfeng, Ҫolak, Selҫuk, van Pelt, Sake I, Kroes, Wilma G M, Teunisse, Amina F A S, Alsafadi, Samar, van Duinen, Sjoerd G, Luyten, Gregorius P M, van der Velden, Pieter A, Amaro, Adriana, Pfeffer, Ulrich, Jochemsen, Aart G, Jager, Martine J

“…Expression of DNA repair genes was studied in uveal melanoma (UM) in order to identify genes that may play a role in metastases formation. We searched for…”
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NeuroGenetic approach for combinatorial optimization: an exploratory analysis by Agarwal, Anurag, Colak, Selcuk, Deane, Jason

“…Given the NP-Hard nature of many optimization problems, it is often impractical to obtain optimal solutions to large-scale problems in reasonable computing…”
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Improvement heuristic for the flow-shop scheduling problem: An adaptive-learning approach by Agarwal, Anurag, Colak, Selcuk, Eryarsoy, Enes

“…We propose an improvement-heuristic approach for the general flow-shop problem ( n/ m/ C max) based on the idea of adaptive learning. The approach employs a…”
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Heuristics and augmented neural networks for task scheduling with non-identical machines by Agarwal, Anurag, Colak, Selcuk, Jacob, Varghese S., Pirkul, Hasan

“…We propose new heuristics along with an augmented-neural-network (AugNN) formulation for solving the makespan minimization task-scheduling problem for the…”
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Improvement heuristic for the flow-shop scheduling problem : An adaptive-learning approach : Flowshop scheduling research by AGARWAL, Anurag, COLAK, Selcuk, ERYARSOY, Enes

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Non-greedy heuristics and augmented neural networks for the open-shop scheduling problem by Colak, Selcuk, Agarwal, Anurag

“…In this paper we propose some non‐greedy heuristics and develop an Augmented‐Neural‐Network (AugNN) formulation for solving the classical open‐shop scheduling…”
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Üretim yönetimi: Editör, Selçuk Çolak by Çolak, Selçuk

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