Search Results - "Col, Jessica Dal"
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Role of Human Leukocyte Antigen System as A Predictive Biomarker for Checkpoint-Based Immunotherapy in Cancer Patients
Published in International journal of molecular sciences (01-10-2020)“…Recent advances in cancer immunotherapy have clearly shown that checkpoint-based immunotherapy is effective in a small subgroup of cancer patients. However, no…”
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Dendritic Cells and Immunogenic Cancer Cell Death: A Combination for Improving Antitumor Immunity
Published in Pharmaceutics (12-03-2020)“…The safety and feasibility of dendritic cell (DC)-based immunotherapies in cancer management have been well documented after more than twenty-five years of…”
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rs822336 binding to C/EBPβ and NFIC modulates induction of PD-L1 expression and predicts anti-PD-1/PD-L1 therapy in advanced NSCLC
Published in Molecular cancer (25-03-2024)“…Efficient predictive biomarkers are needed for immune checkpoint inhibitor (ICI)-based immunotherapy in non-small cell lung cancer (NSCLC). Testing the…”
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Distinct functional significance of Akt and mTOR constitutive activation in mantle cell lymphoma
Published in Blood (15-05-2008)“…Functional characterization of signaling pathways that critically control mantle cell lymphoma (MCL) cell growth and survival is relevant to designing new…”
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NFATc2 Is a Potential Therapeutic Target in Human Melanoma
Published in Journal of investigative dermatology (01-11-2012)“…The identification of intracellular signaling pathways that promote cell proliferation and resistance to cell death may lead to the development of improved…”
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Phospholipid scramblase 1 as a critical node at the crossroad between autophagy and apoptosis in mantle cell lymphoma
Published in Oncotarget (05-07-2016)“…Mantle cell lymphoma (MCL) is an aggressive haematological malignancy in which the response to therapy can be limited by aberrantly activated molecular and…”
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The PP2A inhibitor SET regulates granzyme B expression in human natural killer cells
Published in Blood (24-02-2011)“…The ability of natural killer (NK) cells to kill malignant or infected cells depends on the integration of signals from different families of cell surface…”
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Immunogenic Apoptosis as a Novel Tool for Anticancer Vaccine Development
Published in International journal of molecular sciences (16-02-2018)“…Immunogenic apoptosis, or more appropriately called immunogenic cell death (ICD), is a recently described form of apoptosis induced by a specific set of…”
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hTERT inhibits the Epstein‐Barr virus lytic cycle and promotes the proliferation of primary B lymphocytes: Implications for EBV‐driven lymphomagenesis
Published in International journal of cancer (01-08-2007)“…Transformation of primary B lymphocytes by Epstein‐Barr Virus (EBV) requires the establishment of a latent infection, the expression of several latent viral…”
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Editorial: Rising stars in molecular and cellular oncology 2022
Published in Frontiers in oncology (23-01-2023)Get full text
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Enhanced Expression of CD47 Is Associated With Off-Target Resistance to Tyrosine Kinase Inhibitor Gefitinib in NSCLC
Published in Frontiers in immunology (31-01-2020)“…Mutual interactions between cancer cells and the tumor microenvironment importantly contribute to the development of tyrosine kinase inhibitor (TKI) resistance…”
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TGF-beta utilizes SMAD3 to inhibit CD16-mediated IFN-gamma production and antibody-dependent cellular cytotoxicity in human NK cells
Published in The Journal of immunology (1950) (15-09-2008)“…TGF-beta can be a potent suppressor of lymphocyte effector cell functions and can mediate these effects via distinct molecular pathways. The role of TGF-beta…”
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A Novel Dendritic Cell-Based Vaccination Protocol to Stimulate Immunosurveillance of Aggressive Cancers
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2019)“…A major challenge in the development of a successful tumor vaccination is to break immune tolerance and to sensitize efficiently the immune system toward…”
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RNA-Binding Proteins as a Molecular Link between COPD and Lung Cancer
Published in Chronic obstructive pulmonary disease (31-12-2023)“…Chronic obstructive pulmonary disease (COPD) represents an independent risk factor for lung cancer development. Accelerated cell senescence, induced by…”
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Phospholipid scramblase 1: a protein with multiple functions via multiple molecular interactors
Published in Cell communication and signaling (01-06-2022)“…Phospholipid scramblase 1 (PLSCR1) is the most studied protein of the scramblase family. Originally, it was identified as a membrane protein involved in…”
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Damage-Associated Molecular Patterns Modulation by microRNA: Relevance on Immunogenic Cell Death and Cancer Treatment Outcome
Published in Cancers (24-05-2021)“…Immunogenic cell death (ICD) in cancer is a functionally unique regulated form of stress-mediated cell death that activates both the innate and adaptive immune…”
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Editorial: Dendritic Cell-Based Immunotherapy in Solid and Haematologic Tumors
Published in Frontiers in immunology (31-03-2020)Get full text
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Impact of Genomic Mutation on Melanoma Immune Microenvironment and IFN-1 Pathway-Driven Therapeutic Responses
Published in Cancers (17-07-2024)“…The BRAFV600E mutation, found in approximately 50% of melanoma cases, plays a crucial role in the activation of the MAPK/ERK signaling pathway, which promotes…”
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SIRT1 Signaling Is Involved in the Vascular Improvement Induced by Moringa Oleifera Seeds during Aging
Published in Pharmaceuticals (Basel, Switzerland) (18-05-2023)“…Vascular aging is linked to reduce NO bioavailability, endothelial dysfunction, oxidative stress, and inflammation. We previously showed that a 4-week…”
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Peritumoral Immune Infiltrate as a Prognostic Biomarker in Thin Melanoma
Published in Frontiers in immunology (29-09-2020)“…Thin melanomas are tumors less than 1 mm thick according to Breslow classification. Their prognosis is in most cases excellent. However, a small subset of…”
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