Search Results - "Coker, Allison"

MDMA-assisted therapy for severe PTSD: a randomized, double-blind, placebo-controlled phase 3 study by Mitchell, Jennifer M., Bogenschutz, Michael, Lilienstein, Alia, Harrison, Charlotte, Kleiman, Sarah, Parker-Guilbert, Kelly, Ot’alora G., Marcela, Garas, Wael, Paleos, Casey, Gorman, Ingmar, Nicholas, Christopher, Mithoefer, Michael, Carlin, Shannon, Poulter, Bruce, Mithoefer, Ann, Quevedo, Sylvestre, Wells, Gregory, Klaire, Sukhpreet S., van der Kolk, Bessel, Tzarfaty, Keren, Amiaz, Revital, Worthy, Ray, Shannon, Scott, Woolley, Joshua D., Marta, Cole, Gelfand, Yevgeniy, Hapke, Emma, Amar, Simon, Wallach, Yair, Brown, Randall, Hamilton, Scott, Wang, Julie B., Coker, Allison, Matthews, Rebecca, de Boer, Alberdina, Yazar-Klosinski, Berra, Emerson, Amy, Doblin, Rick

“…Post-traumatic stress disorder (PTSD) presents a major public health problem for which currently available treatments are modestly effective. We report the…”
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Effects of MDMA-assisted therapy for PTSD on self-experience by van der Kolk, Bessel A, Wang, Julie B, Yehuda, Rachel, Bedrosian, Leah, Coker, Allison R, Harrison, Charlotte, Mithoefer, Michael, Yazar-Klosinki, Berra, Emerson, Amy, Doblin, Rick

“…There is a resurgence of interest in the therapeutic potential of psychedelic substances such as 3,4-methylenedioxymethamphetamine (MDMA). Primary findings…”
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Altered brain activity and functional connectivity after MDMA-assisted therapy for post-traumatic stress disorder by Singleton, S Parker, Wang, Julie B, Mithoefer, Michael, Hanlon, Colleen, George, Mark S, Mithoefer, Annie, Mithoefer, Oliver, Coker, Allison R, Yazar-Klosinski, Berra, Emerson, Amy, Doblin, Rick, Kuceyeski, Amy

“…3,4-methylenedioxymethamphetamine-assisted therapy (MDMA-AT) for post-traumatic stress disorder (PTSD) has demonstrated promise in multiple clinical trials…”
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Psychedelic drug abuse potential assessment research for new drug applications and Controlled Substances Act scheduling by Henningfield, Jack E., Coe, Marion A., Griffiths, Roland R., Belouin, Sean J., Berger, Ann, Coker, Allison R., Comer, Sandra D., Heal, David J., Hendricks, Peter S., Nichols, Charles D., Sapienza, Frank, Vocci, Frank J., Zia, Farah Z.

“…New medicines containing classic hallucinogenic and entactogenic psychedelic substance are under development for various psychiatric and neurological…”
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The catechol-O-methyltransferase inhibitor tolcapone modulates alcohol consumption and impulsive choice in alcohol use disorder by Coker, Allison R., Weinstein, Dawn N., Vega, Taylor A., Miller, Catriona S., Kayser, Andrew S., Mitchell, Jennifer M.

“…Rationale Individuals suffering from alcohol use disorder (AUD) demonstrate difficulty with decision-making and impulsivity that may be associated with…”
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Reliability in the identification of midbrain dopamine neurons by Margolis, Elyssa B, Coker, Allison R, Driscoll, Joseph R, Lemaître, Anne-Iris, Fields, Howard L

“…Brain regions typically contain intermixed subpopulations of neurons with different connectivity and neurotransmitters. This complicates identification of…”
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Intra-VTA Deltorphin, But Not DPDPE, Induces Place Preference in Ethanol-Drinking Rats: Distinct DOR-1 and DOR-2 Mechanisms Control Ethanol Consumption and Reward by Mitchell, Jennifer M., Margolis, Elyssa B., Coker, Allison R., Allen, Daicia C., Fields, Howard L.

“…Background While there is a growing body of evidence that the delta opioid receptor (DOR) modulates ethanol (EtOH) consumption, development of DOR‐based…”
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Alcohol Self-Administration, Anxiety, and Cortisol Levels Predict Changes in Delta Opioid Receptor Function in the Ventral Tegmental Area by Mitchell, Jennifer M, Margolis, Elyssa B, Coker, Allison R, Fields, Howard L

“…The delta opioid receptor (DOR) agonist DPDPE decreases ethanol (EtOH) consumption when injected into the ventral tegmental area (VTA). We previously showed…”
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The Anticonvulsant Levetiracetam Potentiates Alcohol Consumption in Non-Treatment Seeking Alcohol Abusers by MITCHELL, Jennifer M, GROSSMAN, Leah E, COKER, Allison R, MESSING, Robert O

“…Levetiracetam (Keppra) is a commonly prescribed anticonvulsant that has been shown to attenuate alcohol consumption in an open-label study of…”
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MDMA-Therapy for Trauma Related Disorders by Mitchell, Jennifer, Lilienstein, Alia, Coker, Allison, Yazar-Klosinski, Berra

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Reply to: Caution at psychiatry’s psychedelic frontier and Challenges with benchmarking of MDMA-assisted psychotherapy by Mitchell, Jennifer, Coker, Allison, Yazar-Klosinski, Berra

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The effects of MDMA-assisted therapy on alcohol and substance use in a phase 3 trial for treatment of severe PTSD by Nicholas, Christopher R., Wang, Julie B., Coker, Allison, Mitchell, Jennifer M., Klaire, Sukhpreet S., Yazar-Klosinski, Berra, Emerson, Amy, Brown, Randy T., Doblin, Rick

“…Post-traumatic stress disorder (PTSD) is commonly associated with alcohol and substance use disorders (ASUD). A randomized, placebo-controlled, phase 3 trial…”
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Scale up isolation, characterization and in vivo evaluation of aaptamine from A. aaptos suggests its anti‐depressant effects are linked to the DOP receptor by Lambu, Eptisam, McIntosh, Nicole L., Coker, Allison, Li, Fei, Fewerda, Madeline, Milan‐Lobo, Laura, He, Li, Crews, Philip, Whistler, Jennifer L., Johnson, Tyler A.

“…Recently we discovered that the aaptamine class of marine sponge derived natural products exhibit selective agonist activity in vitro for the delta opioid…”
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Scaling Up: Multisite Open-Label Clinical Trials of MDMA-Assisted Therapy for Severe Posttraumatic Stress Disorder by Wang, Julie B., Lin, Jessica, Bedrosian, Leah, Coker, Allison, Jerome, Ilsa, Feduccia, Allison, Lilienstein, Alia, Harrison, Charlotte, Heimler, Elizabeth, Mithoefer, Michael, Mithoefer, Annie, Ot’alora G., Marcela, Poulter, Bruce, Carlin, Shannon, Matthews, Rebecca, Yazar-Klosinski, Berra, Emerson, Amy, Doblin, Rick

“…Background: Posttraumatic stress disorder (PTSD) is a debilitating mental health condition associated with serious adverse health outcomes and functional…”
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Changes in behavioral effects of delta opioid receptor agonists with ethanol consumption by Coker, Allison

“…Alcohol use disorders (AUDs) are a common problem with few effective treatment options. There are only three FDA-approved drugs for the treatment of AUDs, all…”
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MDMA-Assisted Therapy for Severe PTSD: A Randomized, Double-Blind, Placebo-Controlled Phase 3 Study by Mitchell, Jennifer M, Bogenschutz, Michael, Lilienstein, Alia, Harrison, Charlotte, Kleiman, Sarah, Parker-Guilbert, Kelly, Ot'alora G, Marcela, Garas, Wael, Paleos, Casey, Gorman, Ingmar, Nicholas, Christopher, Mithoefer, Michael, Carlin, Shannon, Poulter, Bruce, Mithoefer, Ann, Quevedo, Sylvestre, Wells, Gregory, Klaire, Sukhpreet S, van der Kolk, Bessel, Tzarfaty, Keren, Amiaz, Revital, Worthy, Ray, Shannon, Scott, Woolley, Joshua D, Marta, Cole, Gelfand, Yevgeniy, Hapke, Emma, Amar, Simon, Wallach, Yair, Brown, Randall, Hamilton, Scott, Wang, Julie B, Coker, Allison, Matthews, Rebecca, de Boer, Alberdina, Yazar-Klosinski, Berra, Emerson, Amy, Doblin, Rick

“…Post-traumatic stress disorder (PTSD) presents a major public health problem for which currently available treatments are modestly effective. We report the…”
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