Search Results - "Cojocaru, Radu I"
-
1
Conditional ablation of the Notch2 receptor in the ocular lens
Published in Developmental biology (15-02-2012)“…Notch signaling is essential for proper lens development, however the specific requirements of individual Notch receptors have not been investigated. Here we…”
Get full text
Journal Article -
2
Ciliary neurotrophic factor induces genes associated with inflammation and gliosis in the retina: a gene profiling study of flow-sorted, Müller cells
Published in PloS one (2011)“…Ciliary neurotrophic factor (CNTF), a member of the interleukin-6 cytokine family, has been implicated in the development, differentiation and survival of…”
Get full text
Journal Article -
3
Distinct signature of altered homeostasis in aging rod photoreceptors: implications for retinal diseases
Published in PloS one (08-11-2010)“…Advanced age contributes to clinical manifestations of many retinopathies and represents a major risk factor for age-related macular degeneration, a leading…”
Get full text
Journal Article -
4
Protective gene expression changes elicited by an inherited defect in photoreceptor structure
Published in PloS one (20-02-2012)“…Inherited defects in retinal photoreceptor structure impair visual transduction, disrupt relationship with the retinal pigment epithelium (RPE), and compromise…”
Get full text
Journal Article -
5
Preservation of cone photoreceptors after a rapid yet transient degeneration and remodeling in cone-only Nrl-/- mouse retina
Published in The Journal of neuroscience (11-01-2012)“…Cone photoreceptors are the primary initiator of visual transduction in the human retina. Dysfunction or death of rod photoreceptors precedes cone loss in many…”
Get full text
Journal Article -
6
Mutations in a BTB-Kelch Protein, KLHL7, Cause Autosomal-Dominant Retinitis Pigmentosa
Published in American journal of human genetics (12-06-2009)“…Retinitis pigmentosa (RP) refers to a genetically heterogeneous group of progressive neurodegenerative diseases that result in dysfunction and/or death of rod…”
Get full text
Journal Article