Search Results - "Cojocaru, Laura"

Recommendations for Validation of LC-MS/MS Bioanalytical Methods for Protein Biotherapeutics by Jenkins, Rand, Duggan, Jeffrey X., Aubry, Anne-Françoise, Zeng, Jianing, Lee, Jean W., Cojocaru, Laura, Dufield, Dawn, Garofolo, Fabio, Kaur, Surinder, Schultz, Gary A., Xu, Keyang, Yang, Ziping, Yu, John, Zhang, Yan J., Vazvaei, Faye

“…ABSTRACT This paper represents the consensus views of a cross-section of companies and organizations from the USA and Canada regarding the validation and…”
Get full text

2014 White Paper on recent issues in bioanalysis: a full immersion in bioanalysis (Part 2 - hybrid LBA/LCMS, ELN & regulatory agencies' input) by Dufield, Dawn, Neubert, Hendrik, Garofolo, Fabio, Kirkovsky, Leo, Stevenson, Lauren, Dumont, Isabelle, Kaur, Surinder, Xu, Keyang, Alley, Stephen C, Szapacs, Matthew, Arnold, Mark, Bansal, Surendra, Haidar, Sam, Welink, Jan, Le Blaye, Olivier, Wakelin-Smith, Jason, Whale, Emma, Ishii-Watabe, Akiko, Bustard, Mark, Katori, Noriko, Amaravadi, Lakshmi, Aubry, Anne-Françoise, Beaver, Chris, Bergeron, Annik, Cai, Xiao-Yan, Cojocaru, Laura, DeSilva, Binodh, Duggan, Jeff, Fluhler, Eric, Gorovits, Boris, Gupta, Swati, Hayes, Roger, Ho, Stacy, Ingelse, Benno, King, Lindsay, Lévesque, Ann, Lowes, Steve, Ma, Mark, Musuku, Adrien, Myler, Heather, Olah, Timothy, Patel, Shefali, Rose, Mark, Schultz, Gary, Smeraglia, John, Swanson, Steven, Torri, Albert, Vazvaei, Faye, Wilson, Amanda, Woolf, Eric, Xue, Li, Yang, Tong-Yuan

“…The 2014 8th Workshop on Recent Issues in Bioanalysis (8th WRIB), a 5-day full immersion in the evolving field of bioanalysis, took place in Universal City,…”
Get full text

2014 White Paper on recent issues in bioanalysis: a full immersion in bioanalysis (Part 1--small molecules by LCMS) by Fluhler, Eric, Hayes, Roger, Garofolo, Fabio, Dumont, Isabelle, Blaye, Olivier Le, Arnold, Mark, Bansal, Surendra, Verhaeghe, Tom, Wilson, Amanda, Stevenson, Lauren, Myler, Heather, Bauer, Ronald, Bergeron, Annik, Bustard, Mark, Cai, Xiao-Yan, Carbone, Mary, Cojocaru, Laura, Desai-Krieger, Daksha, Duggan, Jeff, Haidar, Sam, Ho, Stacy, Ingelse, Benno, Katori, Noriko, Lévesque, Ann, Lowes, Steve, Ma, Mark, Mettke, Katalina, Michon, Josée, Musuku, Adrien, Olah, Timothy, Patel, Shefali, Rose, Mark, Schultz, Gary, Smeraglia, John, Spooner, Neil, Stouffer, Bruce, Vazvaei, Faye, Wakelin-Smith, Jason, Wang, Jian, Welink, Jan, Whale, Emma, Woolf, Eric, Xue, Li, Yang, Tong-Yuan

“…The 2014 8th Workshop on Recent Issues in Bioanalysis (8th WRIB), a 5-day full immersion in the evolving field of bioanalysis, took place in Universal City,…”
Get full text

Dalbavancin: Quantification in human plasma and urine by a new improved high performance liquid chromatography–tandem mass spectrometry method by Alebic-Kolbah, Tanja, Demers, Roger, Cojocaru, Laura

“…Dalbavancin is a novel second-generation lipoglycopeptide antibiotic with activity against broad range of Gram-positive pathogens. In order to determine the…”
Get full text

Consideration Regarding Current Assets in the Construction Entities by Cojocaru (Alionescu), Laura-Adriana

“…Accounting for current assets mainly aims to obtain useful information on the management of their best in order to make management decisions. Counting…”
Get full text

Financial System Development and Economic Growth in Transition Economies: New Empirical Evidence from the CEE and CIS Countries by Cojocaru, Laura, Falaris, Evangelos M., Hoffman, Saul D., Miller, Jeffrey B.

“…We examine the role of financial development in economic growth in the former Communist countries of Central and Eastern Europe and the Commonwealth of…”
Get full text

Multiplexed LC-MS/MS method for the simultaneous quantitation of three novel hepatitis C antivirals, daclatasvir, asunaprevir, and beclabuvir in human plasma by Jiang, Hao, Kandoussi, Hamza, Zeng, Jianing, Wang, Jian, Demers, Roger, Eley, Timothy, He, Bing, Burrell, Richard, Easter, John, Kadiyala, Pathanjali, Pursley, Janice, Cojocaru, Laura, Baker, Chanda, Ryan, John, Aubry, Anne-Françoise, Arnold, Mark E.

“…•Simultaneous quantitation of three novel HCV drugs in human plasma by LC-MS/MS.•The validation results demonstrate the method is accurate, precise, and…”
Get full text

A sensitive and accurate liquid chromatography–tandem mass spectrometry method for quantitative determination of the novel hepatitis C NS5A inhibitor BMS-790052 (daclastasvir) in human plasma and urine by Jiang, Hao, Zeng, Jianing, Kandoussi, Hamza, Liu, Yifei, Wang, Xiaodong, Bifano, Marc, Cojocaru, Laura, Ryan, John, Arnold, Mark E.

“…► We developed a sensitive and accurate LC–MS/MS method with the LLOQ at 50pg/mL. ► A doubly charged precursor ion was monitored in +ESI/SRM mode, which showed…”
Get full text

A highly sensitive and selective LC–MS/MS method to quantify asunaprevir, an HCV NS3 protease inhibitor, in human plasma in support of pharmacokinetic studies by Kandoussi, Hamza, Jiang, Hao, Zeng, Jianing, Zheng, Naiyu, Kadiyala, Pathanjali, Eley, Timothy, He, Bing, Garimella, Tushar, Demers, Roger, Cojocaru, Laura, Aubry, Anne-Françoise, Arnold, Mark E.

“…[Display omitted] •Sensitive LC–MS/MS assay was developed to quantify asunaprevir in human plasma.•CHAPS was added during LLE to prevent non-specific binding…”
Get full text

Primary Prevention Programme for Burnout-Endangered Teachers : Follow-Up Effectiveness of a Combined Group and Individual Intervention of AFA Breathing Therapy by Loew, Thomas, Goetz, Katja, Hornung, Regina, Cojocaru, Laura, Lahmann, Claas, Tritt, Karin

“…Background. Early retirement of teachers due to burnout is frequent in Germany. In this study short- and medium-term effects of AFA breathing therapy were…”
Get full text

Liquid chromatography and tandem mass spectrometry method for the quantitative determination of saxagliptin and its major pharmacologically active 5-monohydroxy metabolite in human plasma: Method validation and overcoming specific and non-specific binding at low concentrations by Xu, Xiaohui (Sophia), Demers, Roger, Gu, Huidong, Christopher, Lisa J., Su, Hong, Cojocaru, Laura, Boulton, David W., Kirby, Mark, Stouffer, Bruce, Humphreys, William G., Arnold, Mark E.

“…► A liquid chromatography and tandem mass spectrometry (LC–MS/MS) method was developed and validated to simultaneously determine the concentrations of…”
Get full text

Recommendations on biomarker bioanalytical method validation by GCC by Hougton, Richard, Gouty, Dominique, Allinson, John, Green, Rachel, Losauro, Mike, Lowes, Steve, LeLacheur, Richard, Garofolo, Fabio, Couerbe, Philippe, Bronner, Stéphane, Struwe, Petra, Schiebl, Christine, Sangster, Timothy, Pattison, Colin, Islam, Rafiq, Garofolo, Wei, Pawula, Maria, Buonarati, Mike, Hayes, Roger, Cameron, Mark, Nicholson, Robert, Harman, Jake, Wieling, Jaap, De Boer, Theo, Reuschel, Scott, Cojocaru, Laura, Harter, Tammy, Malone, Michele, Nowatzke, William

“…The 5th GCC in Barcelona (Spain) and 6th GCC in San Antonio (TX, USA) events provided a unique opportunity for CRO leaders to openly share opinions and…”
Get more information

Sensitive and accurate liquid chromatography–tandem mass spectrometry methods for quantitative determination of a novel hepatitis C NS5B inhibitor BMS-791325 and its active metabolite in human plasma and urine by Jiang, Hao, Demers, Roger, Kandoussi, Hamza, Burrell, Richard, Eley, Timothy, Kadiyala, Pathanjali, Cojocaru, Laura, Baker, Chanda, Ryan, John, Aubry, Anne-Françoise, Arnold, Mark E., Zeng, Jianing

“…•Quantitation of BMS-791325 and active metabolite in plasma and urine by LC–MS/MS.•The validation results demonstrate the method is accurate, precise, and…”
Get full text

2014 White Paper on recent issues in bioanalysis: a full immersion in bioanalysis (Part 3 - LBA and immunogenicity) by Stevenson, Lauren, Amaravadi, Lakshmi, Myler, Heather, Salazar-Fontana, Laura, Gorovits, Boris, Kirshner, Susan, Xue, Li, Garofolo, Fabio, Alley, Stephen C, Thway, Theingi, Joyce, Alison, Bansal, Surendra, Beaver, Chris, Bergeron, Annik, Cai, Xiao-Yan, Cojocaru, Laura, DeSilva, Binodh, Dumont, Isabelle, Fluhler, Eric, Fraser, Stephanie, Gouty, Dominique, Gupta, Swati, Haidar, Sam, Hayes, Roger, Ingelse, Benno, Ishii-Watabe, Akiko, Kaur, Surinder, King, Lindsay, Laterza, Omar, Leung, Sheldon, Lévesque, Ann, Ma, Mark, Petit-Frere, Corinne, Pillutla, Renuka, Rose, Mark, Schultz, Gary, Smeraglia, John, Swanson, Steven, Torri, Albert, Vazvaei, Faye, Wakelin-Smith, Jason, Wilson, Amanda, Woolf, Eric, Yang, Tong-Yuan

“…The 2014 8th Workshop on Recent Issues in Bioanalysis (8th WRIB), a 5-day full immersion in the evolving field of bioanalysis, took place in Universal City,…”
Get full text

Recommendations on: internal standard criteria, stability, incurred sample reanalysis and recent 483s by the Global CRO Council for Bioanalysis by Lowes, Steve, Jersey, Jim, Shoup, Ronald, Garofolo, Fabio, Savoie, Natasha, Mortz, Ejvind, Needham, Shane, Caturla, Maria Cruz, Steffen, Ray, Sheldon, Curtis, Hayes, Roger, Samuels, Tim, Di Donato, Lorella, Kamerud, John, Michael, Steve, Lin, Zhongping John, Hillier, Jim, Moussallie, Marc, de Souza Teixeira, Leonardo, Rocci, Mario, Buonarati, Mike, Truog, James, Hussain, Saleh, Lundberg, Richard, Breau, Alan, Zhang, Tianyi, Jonker, Jianine, Berger, Neil, Gagnon-Carignan, Sofi, Nehls, Corey, Nicholson, Robert, Hilhorst, Martijn, Karnik, Shane, de Boer, Theo, Houghton, Richard, Smith, Kirk, Cojocaru, Laura, Allen, Mike, Harter, Tammy, Fatmi, Saadya, Sayyarpour, Farhad, Vija, Jenifer, Malone, Michele, Heller, Dennis

“…"The Global CRO Council (GCC) for Bioanalysis was formed in an effort to bring together many CRO leaders to openly discuss bioanalysis and the regulatory…”
Get more information

Recommendations on incurred sample stability (ISS) by GCC by Lowes, Steve, LeLacheur, Richard, Shoup, Ronald, Garofolo, Fabio, Dumont, Isabelle, Martinez, Suzanne, Zimmer, Jennifer, Caturla, Maria Cruz, Couerbe, Philippe, Awaiye, Kayode, Fatmi, Saadya, Farmen, Raymond, Sheldon, Curtis, Bower, Joseph, Fiscella, Michele, Fast, Douglas, Cape, Stephanie, Hulse, Jim, Kamerud, John, Zhang, Tee, Pasas-Farmer, Stephanie, Garofolo, Wei, Moussallie, Marc, Rocci, Mario, Allinson, John, Gouty, Dominique, Buonarati, Mike, Boudreau, Nadine, Pellerin, Brigitte, Lin, Jenny, Xu, Allan, Hayes, Roger, Bouhajib, Mohammed, Stipancic, Mary, Nicholson, Robert, Nehls, Corey, Warren, Mark, Karnik, Shane, Houghton, Richard, Stovold, Craig, Reuschel, Scott, Cojocaru, Laura, Marcelletti, John, Fang, Xinping, Smith, Ian, Watson, Andrea

“…The topic of incurred sample stability (ISS) has generated considerable discussion within the bioanalytical community in recent years. The subject was an…”
Get full text

The 10th GCC Closed Forum: rejected data, GCP in bioanalysis, extract stability, BAV, processed batch acceptance, matrix stability, critical reagents, ELN and data integrity and counteracting fraud by Cape, Stephanie, Islam, Rafiq, Nehls, Corey, Allinson, John, Safavi, Afshin, Bennett, Patrick, Hulse, James, Beaver, Chris, Khan, Masood, Karnik, Shane, Caturla, Maria Cruz, Lowes, Steve, Iordachescu, Adriana, Silvestro, Luigi, Tayyem, Rabab, Shoup, Ron, Mowery, Stephanie, Keyhani, Anahita, Wakefield, Andrea, Li, Yinghe, Zimmer, Jennifer, Torres, Javier, Couerbe, Philippe, Khadang, Ardeshir, Bourdage, James, Hughes, Nicola, Awaiye, Kayode, Matthews, Brent, Fatmi, Saadya, Johnson, Rhonda, Satterwhite, Christina, Yu, Mathilde, Lin, Jenny, Cojocaru, Laura, Fiscella, Michele, Thomas, Eric, Kurylak, Kai, Kamerud, John, Lin, Zhongping (John), Garofolo, Wei, Savoie, Natasha, Buonarati, Mike, Boudreau, Nadine, Williard, Clark, Liu, Yansheng, Warrino, Dominic, Kale, Prashant, Adcock, Neil, Shekar, Radha, O'Connor, Edward, Ritzen, Hanna, Sanchez, Christina, Hayes, Roger, Bouhajib, Mohammed, Savu, Simona Rizea, Stouffer, Bruce, Tabler, Edward, Tu, Jing, Briscoe, Chad, der Strate, Barry van, Rhyne, Paul, Conliffe, Phyllis, DuBey, Ira, Yamashita, Jim, Tang, Daniel, Groeber, Elizabeth, Vija, Jenifer, Malone, Michele, Osman, Mohamed

“…The 10th Global CRO Council (GCC) Closed Forum was held in Orlando, FL, USA on 18 April 2016. In attendance were decision makers from international CRO member…”
Get full text

Quantitative determination of free/bound atazanavir via high-throughput equilibrium dialysis and LC-MS/MS, and the application in ex vivo samples by Xu, Xiaohui Sophia, Rose, Anne, Demers, Roger, Eley, Timothy, Ryan, John, Stouffer, Bruce, Cojocaru, Laura, Arnold, Mark

“…The determination of drug-protein binding is important in the pharmaceutical development process because of the impact of protein binding on both the…”
Get full text

9th GCC closed forum: CAPA in regulated bioanalysis; method robustness, biosimilars, preclinical method validation, endogenous biomarkers, whole blood stability, regulatory audit experiences and electronic laboratory notebooks by Hayes, Roger, LeLacheur, Richard, Dumont, Isabelle, Couerbe, Philippe, Safavi, Afshin, Islam, Rafiq, Pattison, Colin, Cape, Stephanie, Rocci, Mario, Briscoe, Chad, Cojocaru, Laura, Groeber, Elizabeth, Silvestro, Luigi, Bravo, Jennifer, Shoup, Ron, Verville, Manon, Zimmer, Jennifer, Caturla, Maria Cruz, Khadang, Ardeshir, Bourdage, James, Hughes, Nicola, Fatmi, Saadya, Di Donato, Lorella, Sheldon, Curtis, Keyhani, Anahita, Satterwhite, Christina, Yu, Mathilde, Fiscella, Michele, Hulse, James, Lin, Zhongping John, Garofolo, Wei, Savoie, Natasha, Xiao, Yi Qun, Kurylak, Kai, Harris, Sarah, Saxena, Manju, Buonarati, Mike, Lévesque, Ann, Boudreau, Nadine, Lin, Jenny, Khan, Masood U, Ray, Gene, Liu, Yansheng, Xu, Allan, Soni, Gunjan, Ward, Ian, Kingsley, Clare, Ritzén, Hanna, Tabler, Edward, Nicholson, Bob, Bennett, Patrick, van de Merbel, Nico, Karnik, Shane, Bouhajib, Mohammed, Wieling, Jaap, Mulvana, Daniel, Ingelse, Benno, Allen, Mike, Malone, Michele, Fang, Xinping

“…The 9th GCCClosed Forum was held just prior to the 2015 Workshop on Recent Issues in Bioanalysis (WRIB) in Miami, FL, USA on 13 April 2015. In attendance were…”
Get full text

7th GCC Insights: incurred samples use; fit-for-purpose validation, solution stability, electronic laboratory notebook and hyperlipidemic matrix testing by Rocci, Mario, Lowes, Steve, Shoup, Ronald, Garofolo, Fabio, Farmen, Raymond, Zhang, Tianyi, Allinson, John, Gouty, Dominique, Hayes, Roger, Nicholson, Robert, Houghton, Richard, Dumont, Isabelle, LeLacheur, Richard, Zimmer, Jennifer, Cruz Caturla, Maria, Couerbe, Philippe, Awaiye, Kayode, Fatmi, Saadya, Sheldon, Curtis, Bower, Joseph, Fiscella, Michelle, Fast, Douglas, Cape, Stephanie, Hulse, Jim, Kamerud, John, Pasas-Farmer, Stephanie, Garofolo, Wei, Moussallie, Marc, Buonarati, Mike, Boudreau, Nadine, Pellerin, Brigitte, Lin, Jenny, Xu, Allan, Bouhajib, Mohammed, Stipancic, Mary, Nehls, Corey, Warren, Mark, Karnik, Shane, Stovold, Craig, Reuschel, Scott, Cojocaru, Laura, Marcelletti, John, Fang, Xinping, Smith, Ian, Watson, Andrea

Get full text