Search Results - "Coin, F"

XPC is an RNA polymerase II cofactor recruiting ATAC to promoters by interacting with E2F1 by Bidon, B., Iltis, I., Semer, M., Nagy, Z., Larnicol, A., Cribier, A., Benkirane, M., Coin, F., Egly, J-M., Le May, N.

“…The DNA damage sensor XPC is involved in nucleotide excision repair. Here we show that in the absence of damage, XPC co-localizes with RNA polymerase II (Pol…”
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DNA repair complex licenses acetylation of H2A.Z.1 by KAT2A during transcription by Semer, M., Bidon, B., Larnicol, A., Caliskan, G., Catez, P., Egly, J. M., Coin, F., Le May, N.

“…Post-translational modifications of histone variant H2A.Z accompany gene transactivation, but its modifying enzymes still remain elusive. Here, we reveal a…”
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Mutations in XPB and XPD helicases found in xeroderma pigmentosum patients impair the transcription function of TFIIH by Coin, Frédéric, Bergmann, Etienne, Tremeau-Bravard, Alexandre, Egly, Jean-Marc

“…As part of TFIIH, XPB and XPD helicases have been shown to play a role in nucleotide excision repair (NER). Mutations in these subunits are associated with…”
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Mechanism of Promoter Melting by the Xeroderma Pigmentosum Complementation Group B Helicase of Transcription Factor IIH Revealed by Protein-DNA Photo-Cross-Linking by Douziech, Maxime, Coin, Frédéric, Chipoulet, Jean-Marc, Arai, Yoko, Ohkuma, Yoshiaki, Egly, Jean-Marc, Coulombe, Benoit

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Ten years of TFIIH by Coin, F, Egly, J M

“…A complete molecular description of the transcriptionmachinery is now at hand. The essential transcription factors that allow RNA polymerase II (pol II) to…”
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Cellular Strategies for Accommodating Replication-Hindering Adducts in DNA: Control by the SOS Response in Escherichia coli by Koffel-Schwartz, Nicole, Coin, Frédéric, Veaute, Xavier, Robert P. P. Fuchs

“…The replication of double-stranded plasmids containing a single adduct was analyzed in vivo by means of a sequence heterology that marks the two DNA strands…”
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p8/TTD-A as a Repair-Specific TFIIH Subunit by Coin, Frédéric, De Santis, Luca Proietti, Nardo, Tiziana, Zlobinskaya, Olga, Stefanini, Miria, Egly, Jean-Marc

“…How subunits of the transcription/repair factor TFIIH cooperate to allow for the removal of DNA lesions or for the transcription of genes is crucial to…”
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A new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group A by Ranish, Jeffrey A, Egly, Jean-Marc, Raams, Anja, van der Spek, P J, Aebersold, Ruedi, Hoeijmakers, Jan H J, Vermeulen, Wim, Jaspers, Nicolaas G J, Coin, Frederic, Theil, Arjan, Wijgers, Nils, Hoogstraten, Deborah, Argentini, Manuela, Stefanini, Miria, Giglia-Mari, Giuseppina, Botta, Elena

“…DNA repair-deficient trichothiodystrophy (TTD) results from mutations in the XPD and XPB subunits of the DNA repair and transcription factor TFIIH. In a third…”
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Reconstitution of the Transcription Factor TFIIH: Assignment of Functions for the Three Enzymatic Subunits, XPB, XPD, and cdk7 by Tirode, Franck, Busso, Didier, Coin, Frédéric, Egly, Jean-Marc

“…To understand the initiation of the transcription of protein-coding genes, we have dissected the role of the basal transcription/DNA repair factor TFIIH…”
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Nucleotide excision repair of DNA with recombinant human proteins: definition of the minimal set of factors, active forms of TFIIH, and modulation by CAK by Araújo, S J, Tirode, F, Coin, F, Pospiech, H, Syväoja, J E, Stucki, M, Hübscher, U, Egly, J M, Wood, R D

“…During human nucleotide excision repair, damage is recognized, two incisions are made flanking a DNA lesion, and residues are replaced by repair synthesis. A…”
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Ordered Conformational Changes in Damaged DNA Induced by Nucleotide Excision Repair Factors by Tapias, Angels, Auriol, Jerome, Forget, Diane, Enzlin, Jacqueline H, Schärer, Orlando D, Coin, Frederic, Coulombe, Benoit, Egly, Jean-Marc

“…In response to genotoxic attacks, cells activate sophisticated DNA repair pathways such as nucleotide excision repair (NER), which consists of damage removal…”
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Mutations in the XPD helicase gene result in XP and TTD phenotypes, preventing interaction between XPD and the p44 subunit of TFIIH by Fribourg, Sébastien, Pedrini, Antonia Maria, Rodolfo, Carlo, Egly, Jean-Marc, Coin, Frédéric, Marinoni, Jean-Christophe

“…In most cases, xeroderma pigmentosum group D (XP-D) and trichothiodystrophy (TTD) patients carry mutations in the carboxy-terminal domain of the evolutionarily…”
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Phosphorylation of XPB helicase regulates TFIIH nucleotide excision repair activity by Coin, Frédéric, Auriol, Jérome, Tapias, Angel, Clivio, Pascale, Vermeulen, Wim, Egly, Jean-Marc

“…Nucleotide excision repair (NER) removes damage from DNA in a tightly regulated multiprotein process. The xeroderma pigmentosum group B (XPB) helicase subunit…”
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Transcription activities at 8-oxoG lesions in DNA by Larsen, Elisabeth, Kwon, Kyungrim, Coin, Frédéric, Egly, Jean-Marc, Klungland, Arne

“…7,8-Dihydro-8-oxoguanine (8-oxoG) is the most frequent mutagenic lesion caused by oxidative stress. Eukaryotic cells use a specific DNA glycosylase, OGG1, to…”
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Two sides of the same coin: TFIIH complexes in transcription and DNA repair by Zhovmer, Alexander, Oksenych, Valentyn, Coin, Frédéric

“…TFIIH is organized into a seven-subunit core associated with a three-subunit Cdk-activating kinase (CAK) module. TFIIH has roles in both transcription…”
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Oxidation of reduced Cu,Zn superoxide dismutase by molecular oxygen. A kinetic study by Viglino, P, Scarpa, M, Coin, F, Rotilio, G, Rigo, A

“…The rate of oxidation of reduced bovine Cu,Zn superoxide dismutase [ECu(I)] by molecular O2 was studied by magnetic-resonance techniques and was found to be…”
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Solution Structure and Self-association Properties of the p8 TFIIH Subunit Responsible for Trichothiodystrophy by Vitorino, Marc, Coin, Frédéric, Zlobinskaya, Olga, Atkinson, R. Andrew, Moras, Dino, Egly, Jean-Marc, Poterszman, Arnaud, Kieffer, Bruno

“…Trichothiodystrophy (TTD) is a rare hereditary multi-system disorder associated with defects in nucleotide excision repair (NER) and transcription as…”
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TFIIH with Inactive XPD Helicase Functions in Transcription Initiation but Is Defective in DNA Repair by Winkler, G.Sebastiaan, Araújo, Sofia J., Fiedler, Ulrike, Vermeulen, Wim, Coin, Frederic, Egly, Jean-Marc, Hoeijmakers, Jan H.J., Wood, Richard D., Timmers, H.Th.Marc, Weeda, Geert

“…TFIIH is a multisubunit protein complex involved in RNA polymerase II transcription and nucleotide excision repair, which removes a wide variety of DNA lesions…”
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Transcriptional Activators Stimulate DNA Repair by Frit, Philippe, Kwon, Kyungrim, Coin, Frédéric, Auriol, Jérôme, Dubaele, Sandy, Salles, Bernard, Egly, Jean-Marc

“…To counteract the deleterious effects of genotoxic injury, cells have set up a sophisticated network of DNA repair pathways. We show that Gal4-VP16 and RAR…”
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Cisplatin- and UV-damaged DNA lure the basal transcription factor TFIID/TBP by Vichi, Paul, Coin, Frédéric, Renaud, Jean-Paul, Vermeulen, Wim, Hoeijmakers, J.H.J, Moras, Dino, Egly, Jean-Marc

“…A connection between transcription and DNA repair was demonstrated previously through the characterization of TFIIH. Using filter binding as well as in vitro…”
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