Search Results - "Cohn, David"

“The times they are a-changin’” – And how are we managing? by Cohn, David E.

Get full text

Microfluidic affinity separation chip for selective capture and release of label-free ovarian cancer exosomes by Hisey, Colin L, Dorayappan, Kalpana Deepa Priya, Cohn, David E, Selvendiran, Karuppaiyah, Hansford, Derek J

“…Exosomes are nanoscale vesicles found in many bodily fluids which play a significant role in cell-to-cell signaling and contain biomolecules indicative of…”
Get more information

Bokhman Redux: Endometrial cancer “types” in the 21st century by Suarez, Adrian A, Felix, Ashley S, Cohn, David E

“…Abstract In 1983 Jan V. Bokhman, M.D. published a landmark paper entitled “Two Pathogenetic Types of Endometrial Carcinoma” in which an enduring dualistic view…”
Get full text

Hypoxia-induced exosomes contribute to a more aggressive and chemoresistant ovarian cancer phenotype: a novel mechanism linking STAT3/Rab proteins by Dorayappan, Kalpana Deepa Priya, Wanner, Ross, Wallbillich, John J., Saini, Uksha, Zingarelli, Roman, Suarez, Adrian A., Cohn, David E., Selvendiran, Karuppaiyah

“…Hypoxia-mediated tumor progression, metastasis, and drug resistance are major clinical challenges in ovarian cancer. Exosomes released in the hypoxic tumor…”
Get full text

Official American Thoracic Society/Infectious Diseases Society of America/Centers for Disease Control and Prevention Clinical Practice Guidelines: Diagnosis of Tuberculosis in Adults and Children by Lewinsohn, David M., Leonard, Michael K., LoBue, Philip A., Cohn, David L., Daley, Charles L., Desmond, Ed, Keane, Joseph, Lewinsohn, Deborah A., Loeffler, Ann M., Mazurek, Gerald H., O'Brien, Richard J., Pai, Madhukar, Richeldi, Luca, Salfinger, Max, Shinnick, Thomas M., Sterling, Timothy R., Warshauer, David M., Woods, Gail L.

“…Background. Individuals infected with Mycobacterium tuberculosis (Mtb) may develop symptoms and signs of disease (tuberculosis disease) or may have no clinical…”
Get full text

Carboplatin and Paclitaxel for Advanced Endometrial Cancer: Final Overall Survival and Adverse Event Analysis of a Phase III Trial (NRG Oncology/GOG0209) by Miller, David S, Filiaci, Virginia L, Mannel, Robert S, Cohn, David E, Matsumoto, Takashi, Tewari, Krishnansu S, DiSilvestro, Paul, Pearl, Michael L, Argenta, Peter A, Powell, Matthew A, Zweizig, Susan L, Warshal, David P, Hanjani, Parviz, Carney, Michael E, Huang, Helen, Cella, David, Zaino, Richard, Fleming, Gini F

“…Limitations of the paclitaxel-doxorubicin-cisplatin (TAP) regimen in the treatment of endometrial cancer include tolerability and cumbersome scheduling. The…”
Get full text

Randomized Trial of Intravenous Versus Intraperitoneal Chemotherapy Plus Bevacizumab in Advanced Ovarian Carcinoma: An NRG Oncology/Gynecologic Oncology Group Study by Walker, Joan L, Brady, Mark F, Wenzel, Lari, Fleming, Gini F, Huang, Helen Q, DiSilvestro, Paul A, Fujiwara, Keiichi, Alberts, David S, Zheng, Wenxin, Tewari, Krishnansu S, Cohn, David E, Powell, Matthew A, Van Le, Linda, Davidson, Susan A, Gray, Heidi J, Rose, Peter G, Aghajanian, Carol, Myers, Tashanna, Alvarez Secord, Angeles, Rubin, Stephen C, Mannel, Robert S

“…To evaluate the impact of two different intraperitoneal (IP) chemotherapy regimens on progression-free survival (PFS) among women with newly diagnosed advanced…”
Get full text

Official American Thoracic Society/Infectious Diseases Society of America/Centers for Disease Control and Prevention Clinical Practice Guidelines: Diagnosis of Tuberculosis in Adults and Children by Lewinsohn, David M, Leonard, Michael K, LoBue, Philip A, Cohn, David L, Daley, Charles L, Desmond, Ed, Keane, Joseph, Lewinsohn, Deborah A, Loeffler, Ann M, Mazurek, Gerald H, O'Brien, Richard J, Pai, Madhukar, Richeldi, Luca, Salfinger, Max, Shinnick, Thomas M, Sterling, Timothy R, Warshauer, David M, Woods, Gail L

“…Individuals infected with Mycobacterium tuberculosis (Mtb) may develop symptoms and signs of disease (tuberculosis disease) or may have no clinical evidence of…”
Get full text

Phase III Trial of Four Cisplatin-Containing Doublet Combinations in Stage IVB, Recurrent, or Persistent Cervical Carcinoma: A Gynecologic Oncology Group Study by MONK, Bradley J, SILL, Michael W, MCMEEKIN, D. Scott, COHN, David E, RAMONDETTA, Lois M, BOARDMAN, Cecelia H, BENDA, Jo, CELLA, David

“…Assess toxicity and efficacy of cisplatin (Cis) doublet combinations in advanced and recurrent cervical carcinoma. Patients were randomly assigned to…”
Get full text

Secondary Surgical Cytoreduction for Recurrent Ovarian Cancer by Coleman, Robert L, Spirtos, Nick M, Enserro, Danielle, Herzog, Thomas J, Sabbatini, Paul, Armstrong, Deborah K, Kim, Jae-Weon, Park, Sang-Yoon, Kim, Byoung-Gie, Nam, Joo-Hyun, Fujiwara, Keiichi, Walker, Joan L, Casey, Ann C, Alvarez Secord, Angeles, Rubin, Steve, Chan, John K, DiSilvestro, Paul, Davidson, Susan A, Cohn, David E, Tewari, Krishnansu S, Basen-Engquist, Karen, Huang, Helen Q, Brady, Mark F, Mannel, Robert S

“…An NCI-sponsored, randomized clinical trial tested whether patients with relapsed ovarian cancer might benefit from surgical debulking of tumors followed by…”
Get full text

Inhibition of miR-328-3p Impairs Cancer Stem Cell Function and Prevents Metastasis in Ovarian Cancer by Srivastava, Amit K, Banerjee, Ananya, Cui, Tiantian, Han, Chunhua, Cai, Shurui, Liu, Lu, Wu, Dayong, Cui, Ri, Li, Zaibo, Zhang, Xiaoli, Xie, Guozhen, Selvendiran, Karuppaiyah, Patnaik, Srinivas, Karpf, Adam R, Liu, Jinsong, Cohn, David E, Wang, Qi-En

“…Cancer stem cells (CSC) play a central role in cancer metastasis and development of drug resistance. miRNA are important in regulating CSC properties and are…”
Get full text

Clinicopathologic Significance of Mismatch Repair Defects in Endometrial Cancer: An NRG Oncology/Gynecologic Oncology Group Study by McMeekin, D Scott, Tritchler, David L, Cohn, David E, Mutch, David G, Lankes, Heather A, Geller, Melissa A, Powell, Matthew A, Backes, Floor J, Landrum, Lisa M, Zaino, Richard, Broaddus, Russell D, Ramirez, Nilsa, Gao, Feng, Ali, Shamshad, Darcy, Kathleen M, Pearl, Michael L, DiSilvestro, Paul A, Lele, Shashikant B, Goodfellow, Paul J

“…The clinicopathologic significance of mismatch repair (MMR) defects in endometrioid endometrial cancer (EEC) has not been definitively established. We…”
Get full text

Polymerase ε (POLE) mutations in endometrial cancer: clinical outcomes and implications for Lynch Syndrome testing by Billingsley, Caroline C, Cohn, David E, Mutch, David G, Stephens, Julie A, Suarez, Adrian A, Goodfellow, Paul J

Get full text

The biological significance and clinical applications of exosomes in ovarian cancer by Dorayappan, Kalpana Deepa Priya, Wallbillich, John J, Cohn, David E, Selvendiran, Karuppaiyah

“…Abstract Exosomes are nano-sized (20–100 nm) vesicles released by a variety of cells and are generated within the endosomal system or at the plasma membrane…”
Get full text

The detection of differentially expressed microRNAs from the serum of ovarian cancer patients using a novel real-time PCR platform by Resnick, Kimberly E, Alder, Hansjuerg, Hagan, John P, Richardson, Debra L, Croce, Carlo M, Cohn, David E

“…Abstract Objective To determine the utility of serum miRNAs as biomarkers for epithelial ovarian cancer. Methods Twenty-eight patients with histologically…”
Get full text

Fertility‐sparing surgery and survival among reproductive‐age women with epithelial ovarian cancer in 2 cancer registries by Crafton, Sarah M., Cohn, David E., Llamocca, Elyse N., Louden, Elaine, Rhoades, Jennifer, Felix, Ashley S.

“…Background This study examined predictors of fertility‐sparing surgery (FSS) among reproductive‐age women diagnosed with epithelial ovarian cancer (EOC). In…”
Get full text

Mismatch repair deficiency identifies patients with high‐intermediate–risk (HIR) endometrioid endometrial cancer at the highest risk of recurrence: A prognostic biomarker by Backes, Floor J., Haag, Jennifer, Cosgrove, Casey M., Suarez, Adrian, Cohn, David E., Goodfellow, Paul J.

“…Background The objective of this study was to assess the correlation between mismatch repair (MMR) status, disease recurrence patterns, and recurrence‐free…”
Get full text

Comparison of Anticoagulation Regimens Following Stent Placement for Nonthrombotic Lower Extremity Venous Disease by Arendt, Victoria A., Mabud, Tarub S., Kuo, William T., Jeon, Gyeong S., An, Xiao, Cohn, David M., Fu, Jin Xin, Hofmann, Lawrence V.

“…To determine whether subtherapeutic anticoagulation regimens are noninferior to therapeutic anticoagulation regimens following stent placement for…”
Get full text

Prospective clinical trial of robotic sentinel lymph node assessment with isosulfane blue (ISB) and indocyanine green (ICG) in endometrial cancer and the impact of ultrastaging (NCT01818739) by Backes, Floor J., Cohen, David, Salani, Ritu, Cohn, David E., O'Malley, David M., Fanning, Emily, Suarez, Adrian A., Fowler, Jeffrey M.

“…•SLN assessment in endometrial cancer is feasible and safe with high NPV (99%)•Increasing BMI decreased the chance of successful SLN mapping•Indocyanine green…”
Get full text

Safety and Immunogenicity of the Quadrivalent Human Papillomavirus Vaccine in HIV-1-Infected Men by Wilkin, Timothy, Lee, Jeannette Y., Lensing, Shelly Y., Stier, Elizabeth A., Goldstone, Stephen E., Berry, J. Michael, Jay, Naomi, Aboulafia, David, Cohn, David L., Einstein, Mark H., Saah, Alfred, Mitsuyasu, Ronald T., Palefsky, Joel M.

“…Background. Human immunodeficiency virus type 1 (HIV-1)-infected men are at increased risk for anal cancer. Human papillomavirus (HPV) vaccination may prevent…”
Get full text