Search Results - "Cohen, Paul"

The cellular and functional complexity of thermogenic fat by Cohen, Paul, Kajimura, Shingo

“…Brown and beige adipocytes are mitochondria-enriched cells capable of dissipating energy in the form of heat. These thermogenic fat cells were originally…”
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Cervical cancer by Cohen, Paul A, Jhingran, Anjua, Oaknin, Ana, Denny, Lynette

“…Each year, more than half a million women are diagnosed with cervical cancer and the disease results in over 300 000 deaths worldwide. High-risk subtypes of…”
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Obesity, Adipose Tissue and Vascular Dysfunction by Koenen, Mascha, Hill, Michael A., Cohen, Paul, Sowers, James R.

“…Cardiovascular diseases are the leading cause of death worldwide. Overweight and obesity are strongly associated with comorbidities such as hypertension and…”
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Brown and Beige Fat: Molecular Parts of a Thermogenic Machine by Cohen, Paul, Spiegelman, Bruce M

“…The epidemic of obesity and type 2 diabetes has increased interest in pathways that affect energy balance in mammalian systems. Brown fat, in all of its…”
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Nutritional basis for colonization resistance by human commensal Escherichia coli strains HS and Nissle 1917 against E. coli O157:H7 in the mouse intestine by Maltby, Rosalie, Leatham-Jensen, Mary P, Gibson, Terri, Cohen, Paul S, Conway, Tyrrell

“…Escherichia coli is a single species consisting of many biotypes, some of which are commensal colonizers of mammals and others that cause disease. Humans are…”
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The Multifaceted Roles of PRDM16: Adipose Biology and Beyond by Chi, Jingyi, Cohen, Paul

“…The PRDM [PRDI-BFI (positive regulatory domain I-binding factor 1) and RIZ1 (retinoblastoma protein-interacting zinc finger gene 1) homologous domain…”
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Perioperative transfusion of packed red blood cells in advanced ovarian cancer: a lot to unpack by Cohen, Paul A

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DARPA's Big Mechanism program by Cohen, Paul R

“…Reductionist science produces causal models of small fragments of complicated systems. Causal models of entire systems can be hard to construct because what is…”
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Cell biology of fat storage by Cohen, Paul, Spiegelman, Bruce M

“…The worldwide epidemic of obesity and type 2 diabetes has greatly increased interest in the biology and physiology of adipose tissues. Adipose (fat) cells are…”
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Commensal and Pathogenic Escherichia coli Metabolism in the Gut by Conway, Tyrrell, Cohen, Paul S

“…E. coli is a ubiquitous member of the intestinal microbiome. This organism resides in a biofilm comprised of a complex microbial community within the mucus…”
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Adaptive thermogenesis in adipocytes: is beige the new brown? by Wu, Jun, Cohen, Paul, Spiegelman, Bruce M

“…One of the most promising areas in the therapeutics for metabolic diseases centers around activation of the pathways of energy expenditure. Brown adipose…”
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Response to: Correspondence on 'Medicolegal, infrastructural,and financial aspects in gynecologic cancer surgery and their implications in decision making processes: Quo Vadis?' by Nevin and Bolton by Allanson, Emma, Cohen, Paul A, Bristow, Robert

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Effective Physical Activity Promotion to Survivors of Cancer Is Likely to Be Home Based and to Require Oncologist Participation by Hardcastle, Sarah J, Cohen, Paul A

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Molecular mechanisms of cancer development in obesity by Khandekar, Melin J., Cohen, Paul, Spiegelman, Bruce M.

“…Obesity is increasing in the developed world, and epidemiological studies indicate that this is accompanied by an increased risk of cancer. This Opinion…”
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A leptin–BDNF pathway regulating sympathetic innervation of adipose tissue by Wang, Putianqi, Loh, Ken H., Wu, Michelle, Morgan, Donald A., Schneeberger, Marc, Yu, Xiaofei, Chi, Jingyi, Kosse, Christin, Kim, Damian, Rahmouni, Kamal, Cohen, Paul, Friedman, Jeffrey

“…Mutations in the leptin gene ( ob ) result in a metabolic disorder that includes severe obesity 1 , and defects in thermogenesis 2 and lipolysis 3 , both of…”
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Questioning the value of margin status in treated cervical precancer by Cohen, Paul A

“…[...]clinicians need to balance the risks of future obstetric harm and inadequate treatment of the premalignant lesion. The corresponding pretest and post-test…”
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Knowledge, attitudes, and practice of oncologists and oncology health care providers in promoting physical activity to cancer survivors: an international survey by Hardcastle, Sarah J., Kane, Robert, Chivers, Paola, Hince, Dana, Dean, Andrew, Higgs, Dominic, Cohen, Paul A.

“…Objective To investigate knowledge, attitudes, and practices of oncologists towards physical activity (PA) in cancer survivors, and the association between…”
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Appearance and disappearance of the mRNA signature characteristic of Tᵣₑg cells in visceral adipose tissue: Age, diet, and PPARγ effects by Cipolletta, Daniela, Cohen, Paul, Spiegelman, Bruce M, Benoist, Christophe, Mathis, Diane

“…Significance A unique population of Foxp3 ⁺CD4 ⁺ regulatory T (T ᵣₑg) cells resides in visceral adipose tissue of lean mice. VAT T ᵣₑgₛ are important…”
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A flexible data schema and system architecture for the virtualization of manufacturing machines (VMM) by Angrish, Atin, Starly, Binil, Lee, Yuan-Shin, Cohen, Paul H.

“…•An Unstructured Data model to represent virtual twins of physical machines.•Stacked architecture for the representation of a virtual manufacturing machine…”
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Factors influencing non-participation in an exercise program and attitudes towards physical activity amongst cancer survivors by Hardcastle, Sarah J., Maxwell-Smith, Chloe, Kamarova, Sviatlana, Lamb, Stephanie, Millar, Lesley, Cohen, Paul A.

“…Purpose The purposes of this study are to investigate factors influencing non-participation in a structured exercise program for cancer survivors and to…”
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