Search Results - "Cohen, O J"

Studies in Subjects with Long-Term Nonprogressive Human Immunodeficiency Virus Infection by Pantaleo, Giuseppe, Menzo, Stefano, Vaccarezza, Mauro, Graziosi, Cecilia, Cohen, Oren J, Demarest, James F, Montefiori, David, Orenstein, Jan M, Fox, Cecil, Schrager, Lewis K, Margolick, Joseph B, Buchbinder, Susan, Giorgi, Janis V, Fauci, Anthony S

“…The typical course of human immunodeficiency virus (HIV) infection includes an acute clinical syndrome of variable severity, a prolonged period of clinical…”
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Neutralizing Antibody Responses to Human Immunodeficiency Virus Type 1 in Primary Infection and Long-Term-Nonprogressive Infection by Pilgrim, Alice K., Pantaleo, Giuseppe, Cohen, Oren J., Fink, Lisa M., Zhou, Ji Ying, Zhou, Jin Tao, Bolognesi, Dani P., Fauci, Anthony S., Montefiori, David C.

“…The role of neutralizing antibodies in human immunodeficiency virus type 1 (HIV-1) infection is poorly understood and was assessed by evaluating responses at…”
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Kinetics of Cytokine Expression during Primary Human Immunodeficiency Virus Type 1 Infection by Graziosi, Cecilia, Gantt, Kira R., Vaccarezza, Mauro, Demarest, James F., Daucher, MaryBeth, Saag, Michael S., Shaw, George M., Quinn, Thomas C., Cohen, Oren J., Welbon, Craig C., Pantaleo, Giuseppe, Fauci, Anthony S.

“…In the present study, we have determined the kinetics of constitutive expression of a panel of cytokines [interleukin (IL) 2, IL-4, IL-6, IL-10, interferon γ…”
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Antiretroviral therapy: time to think strategically by Cohen, O J

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Transmission of Multidrug-Resistant Human Immunodeficiency Virus — The Wake-Up Call by Cohen, Oren J, Fauci, Anthony S

“…The addition of human immunodeficiency virus type 1 (HIV-1)–protease inhibitors to the armamentarium of antiretroviral drugs has dramatically improved the…”
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HIV/AIDS in 1998—Gaining the Upper Hand? by Cohen, Oren J, Fauci, Anthony S

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Benchmarks for antiretroviral therapy by Cohen, O J, Fauci, A S

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Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis by Lum, J J, Cohen, O J, Nie, Z, Weaver, J G, Gomez, T S, Yao, X-J, Lynch, D, Pilon, A A, Hawley, N, Kim, JE, Chen, Z, Montpetit, M, Sanchez-Dardon, J, Cohen, E A, Badley, AD

“…The absence of immune defects that occurs in the syndrome of long-term nonprogressive (LTNP) HIV infection offers insights into the pathophysiology of…”
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Rare mutations in a domain crucial for V3-loop structure prevail in replicating HIV from long-term non-progressors by MENZO, S, SAMPAOLESI, R, VICENZI, E, SANTAGOSTINO, E, LIUZZI, G, CHIRIANNI, A, PIAZZA, M, COHEN, O. J, BAGNARELLI, P, CLEMENTI, M

“…To evaluate the role of the selective forces exerted by the host on the HIV-1 structures involved in viral entry. The V3 region of the env gene was analysed in…”
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Host factors in the pathogenesis of HIV disease by Cohen, Oren J., Kinter, Audrey, Fauci, Anthony S.

“…Summary Host factors play an important role in determining rates of disease progression in human immunodeficiency virus (HIV)‐infected individuals. HIV is able…”
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Host factors that affect sexual transmission of HIV by Cohen, Oren J., Fauci, Anthony S.

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HIV-1 Envelope Induces Activation of Caspase-3 and Cleavage of Focal Adhesion Kinase in Primary Human CD4+T Cells by Cicala, Claudia, Arthos, James, Rubbert, Andrea, Seliq, Sara, Wildt, Kathryn, Cohen, Oren J., Fauci, Anthony S.

“…Binding of HIV type 1 (HIV-1) envelope glycoproteins to the surface of a CD4+T cell transduces intracellular signals through the primary envelope receptor,…”
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Antiretroviral Monotherapy in Early Stage Human Immunodeficiency Virus Disease Has No Detectable Effect on Virus Load in Peripheral Blood and Lymph Nodes by Cohen, Oren J., Pantaleo, Giuseppe, Holodniy, Mark, Fox, Cecil H., Orenstein, Jan M., Schnittman, Steven, Niu, Manette, Graziosi, Cecilia, Pavlakis, George N., Lalezari, Jacob, Bartlett, John A., Steigbigel, Roy T., Cohn, Jonathan, Novak, Richard, McMahon, Deborah, Bilello, John, Fauci, Anthony S.

“…Initiation of antiretroviral monotherapy early in the course of infection with human immunodeficiency virus may result in a temporary slowing in the rate of…”
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Lack of evidence for the dichotomy of TH1 and TH2 predominance in HIV-infected individuals by Graziosi, C, Pantaleo, G, Gantt, K R, Fortin, J P, Demarest, J F, Cohen, O J, Sékaly, R P, Fauci, A S

“…A switch from a T helper 1 (TH1) cytokine phenotype to a TH2 phenotype has been proposed as a critical element in the progression of human immunodeficiency…”
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Evidence for Rapid Disappearance of Initially Expanded HIV-Specific CD8+T Cell Clones during Primary HIV Infection by Pantaleo, Giuseppe, Soudeyns, Hugo, Demarest, James F., Vaccarezza, Mauro, Graziosi, Cecilia, Paolucci, Stefania, Daucher, MaryBeth, Cohen, Oren J., Denis, Francois, Biddison, William E., Sekaly, Rafick P., Fauci, Anthony S.

“…Down-regulation of the initial burst of viremia during primary HIV infection is thought to be mediated predominantly by HIV-specific cytotoxic T lymphocytes,…”
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HIV-1 infection in the lymphoid organs by Graziosi, C, Pantaleo, G, Demarest, J F, Cohen, O J, Vaccarezza, M, Butini, L, Montroni, M, Fauci, A S

“…To develop a model of HIV disease progression. Comparative analysis of viral burden and replication between peripheral blood and lymphoid organs and of the…”
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The Qualitative Nature of the Primary Immune Response to HIV Infection is a Prognosticator of Disease Progression Independent of the Initial Level of Plasma Viremia by Pantaleo, Giuseppe, Demarest, James F., Schacker, Timothy, Vaccarezza, Mauro, Cohen, Oren J., Daucher, Marybeth, Graziosi, Cecilia, Schnitman, Steven S., Quinn, Thomas C., Shaw, George M., Perrin, Luc, Tambussi, Giuseppe, Lazzarin, Adriano, Sekaly, Rafick P., Soudeyns, Hugo, Corey, Lawrence, Fauci, Anthony S.

“…Following infection of the host with a virus, the delicate balance between virus replication/spread and the immune response to the virus determines the outcome…”
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Selection of HIV-Specific Immunogenic Epitopes by Screening Random Peptide Libraries with HIV-1-Positive Sera by Scala, Giuseppe, Chen, Xueni, Liu, Weimin, Telles, Jean Noel, Cohen, Oren J, Vaccarezza, Mauro, Igarashi, Tatsu, Fauci, Anthony S

“…Efforts to develop a protective HIV-1 vaccine have been hindered by difficulties in identifying epitopes capable of inducing broad neutralizing Ab responses…”
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Protection of rhesus macaques against disease progression from pathogenic SHIV-89.6PD by vaccination with phage-displayed HIV-1 epitopes by Scala, Giuseppe, Chen, Xueni, Quinto, Ileana, Liu, Weimin, Chun, Tae-Wook, Shawn Justement, J, Cohen, Oren J, vanCott, Tom C, Iwanicki, Marcin, Lewis, Mark G, Greenhouse, Jack, Barry, Todd, Venzon, David, Fauci, Anthony S

“…The antigenic polymorphism of HIV-1 is a major obstacle in developing an effective vaccine. Accordingly, we screened random peptide libraries (RPLs) displayed…”
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Evolutionary pattern of human immunodeficiency virus (HIV) replication and distribution in lymph nodes following primary infection: Implications for antiviral therapy by Pantaleo, Giuseppe, Cohen, Oren J, Schacker, Timothy, Vaccarezza, Mauro, Graziosi, Cecilia, Rizzardi, G. Paolo, Kahn, James, Fox, Cecil H, Schnittman, Steven M, Schwartz, David H, Corey, Lawrence, Fauci, Anthony S

“…Evolutionary patterns of virus replication and distribution in lymphoid tissue during the early phases of HIV infection have not been delineated. Lymph node…”
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