Search Results - "Cohen, Matthew R."
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Structure of the full-length TRPV2 channel by cryo-EM
Published in Nature communications (29-03-2016)“…Transient receptor potential (TRP) proteins form a superfamily Ca 2+ -permeable cation channels regulated by a range of chemical and physical stimuli…”
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Molecular Architecture and Subunit Organization of TRPA1 Ion Channel Revealed by Electron Microscopy
Published in The Journal of biological chemistry (04-11-2011)“…Transient receptor potential ankyrin 1 (TRPA1) is a non-selective ion channel, which is expressed in nociceptor sensory neurons and transduces chemical,…”
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Nerve Growth Factor Regulates Transient Receptor Potential Vanilloid 2 via Extracellular Signal-Regulated Kinase Signaling To Enhance Neurite Outgrowth in Developing Neurons
Published in Molecular and cellular biology (01-12-2015)“…Neurite outgrowth is key to the formation of functional circuits during neuronal development. Neurotrophins, including nerve growth factor (NGF), increase…”
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Structural Insight into the Assembly of TRPV Channels
Published in Structure (London) (04-02-2014)“…Transient receptor potential (TRP) proteins are a large family of polymodal nonselective cation channels. The TRP vanilloid (TRPV) subfamily consists of six…”
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Understanding the cellular function of TRPV2 channel through generation of specific monoclonal antibodies
Published in PloS one (31-12-2013)“…Transient receptor potential vanilloid 2 (TRPV2) is a Ca(2+)-permeable nonselective cation channel proposed to play a critical role in a wide array of cellular…”
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Structure of Thermally Activated TRP Channels
Published in Current Topics in Membranes (2014)“…Temperature sensation is important for adaptation and survival of organisms. While temperature has the potential to affect all biological macromolecules,…”
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Application of Amphipols for Structure–Functional Analysis of TRP Channels
Published in The Journal of membrane biology (01-10-2014)“…Amphipathic polymers (amphipols), such as A8-35 and SApol, are a new tool for stabilizing integral membrane proteins in detergent-free conditions for…”
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Isoflurane alters energy substrate metabolism to preserve mechanical function in Isolated rat hearts following prolonged no-flow hypothermic storage
Published in Anesthesiology (Philadelphia) (01-02-2003)“…Isoflurane enhances mechanical function in hearts subject to normothermic global or regional ischemia. The authors examined the effectiveness of isoflurane in…”
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Molecular Mechanism of TRPV2 Trafficking in Sensory Neurons
Published in Biophysical journal (28-01-2014)Get full text
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