Search Results - "Cohen, L. S."

Abnormal tau induces cognitive impairment through two different mechanisms: synaptic dysfunction and neuronal loss by Di, J., Cohen, L. S., Corbo, C. P., Phillips, G. R., El Idrissi, A., Alonso, A. D.

“…The hyperphosphorylated microtubule-associated protein tau is present in several neurodegenerative diseases, although the causal relationship remains elusive…”
Get full text

Evaluation of CTPA interpreted as limited in pregnant patients suspected for pulmonary embolism by Cohen, S . L., Wang, J., Mankerian, M., Feizullayeva, C., McCandlish, J. A., Barnaby, D., Sanelli, P., McGinn, T.

“…Purpose The purpose of this study is to determine the rates of CT pulmonary angiography (CTPA) interpreted as limited and severely limited in pregnant patients…”
Get full text

The Structure of the Potassium Channel: Molecular Basis of K$^+$ Conduction and Selectivity by Doyle, Declan A., Cabral, João Morais, Pfuetzner, Richard A., Kuo, Anling, Gulbis, Jacqueline M., Cohen, Steven L., Chait, Brian T., MacKinnon, Roderick

“…The potassium channel from Streptomyces lividans is an integral membrane protein with sequence similarity to all known K$^+$ channels, particularly in the pore…”
Get full text

Dilute versus concentrated vasopressin administration during laparoscopic myomectomy: a randomised controlled trial by Cohen, SL, Senapati, S, Gargiulo, AR, Srouji, SS, Tu, FF, Solnik, J, Hur, H‐C, Vitonis, A, Jonsdottir, GM, Wang, KC, Einarsson, JI

“…Objective To determine if higher‐volume, fixed‐dose administration of vasopressin further reduces blood loss at the time of minimally invasive myomectomy…”
Get full text

Risk of Recurrence of Bipolar Disorder in Pregnant and Nonpregnant Women After Discontinuing Lithium Maintenance by Viguera, Adele C., Nonacs, Ruta, Cohen, Lee S., Tondo, Leonardo, Murray, Aoife, Baldessarini, Ross J.

“…OBJECTIVE: Pregnancy poses major challenges for the treatment of bipolar disorder, and information to guide clinical care remains very sparse. The authors…”
Get full text

Comparative NMR analysis of an 80-residue G protein-coupled receptor fragment in two membrane mimetic environments by Cohen, L.S., Arshava, B., Neumoin, A., Becker, J.M., Güntert, P., Zerbe, O., Naider, F.

“…Fragments of integral membrane proteins have been used to study the physical chemical properties of regions of transporters and receptors. Ste2p(G31-T110) is…”
Get full text

DNA binding of in vitro activated Stat1 alpha, Stat1 beta and truncated Stat1: interaction between NH2‐terminal domains stabilizes binding of two dimers to tandem DNA sites by Vinkemeier, U., Cohen, S. L., Moarefi, I., Chait, B. T., Kuriyan, J., Darnell, J. E.

“…Stat1 alpha, Stat1 beta and a proteolytically defined truncated Stat1 (132–713, Stat1tc) have been prepared from recombinant sources. All three proteins were…”
Get full text

Prevalence of Body Dysmorphic Disorder in a Community Sample of Women by Otto, Michael W., Wilhelm, Sabine, Cohen, Lee S., Harlow, Bernard L.

“…OBJECTIVE: In a large population-based study, the authors examined the prevalence and correlates of body dysmorphic disorder, a debilitating and chronic…”
Get full text

Structural Conservation in Prokaryotic and Eukaryotic Potassium Channels by MacKinnon, Roderick, Cohen, Steven L., Kuo, Anling, Lee, Alice, Chait, Brian T.

“…Toxins from scorpion venom interact with potassium channels. Resin-attached, mutant K$^+$ channels from Streptomyces lividans were used to screen venom from…”
Get full text

Weight-Reducing Effects of the Plasma Protein Encoded by the Obese Gene by Halaas, Jeffrey L., Gajiwala, Ketan S., Maffei, Margherita, Cohen, Steven L., Chait, Brian T., Rabinowitz, Daniel, Lallone, Roger L., Burley, Stephen K., Friedman, Jeffrey M.

“…The gene product of the ob locus is important in the regulation of body weight. The ob product was shown to be present as a 16-kilodalton protein in mouse and…”
Get full text

Serological analysis of human anti-human antibody responses in colon cancer patients treated with repeated doses of humanized monoclonal antibody A33 by RITTER, Gerd, COHEN, Leonard S, WILLIAMS, Clarence JR, RICHARDS, Elizabeth C, OLD, Lloyd J, WELT, Sydney

“…Mouse monoclonal antibody A33 (mAb A33) recognizes a M(r) 43,000 cell surface glycoprotein (designated A33) expressed in human colonic epithelium and colon…”
Get full text

A33scFv-cytosine deaminase: a recombinant protein construct for antibody-directed enzyme-prodrug therapy by DECKERT, P. M, RENNER, C, COHEN, L. S, JUNGBLUTH, A, RITTER, G, BERTINO, J. R, OLD, L. J, WELT, S

“…A recombinant fusion protein of colon carcinoma binding A33 single chain antibody with cytosine deaminase displayed specific antigen binding and enzyme…”
Get full text

Thrombolysis in myocardial infarction (TIMI) trial, phase I: a comparison between intravenous tissue plasminogen activator and intravenous streptokinase: clinical findings through hospital discharge by CHESEBRO, J. H, KNATTERUD, G, MARKIS, J. E, MUELLER, H, PASSAMANI, E. R, POWERS, E. R, RAO, A. K, ROBERTSON, T, ROSS, A, RYAN, T. J, SOBEL, B. E, WILLERSON, J, ROBERTS, R, WILLIAMS, D. O, ZARET, B. L, BRAUNWALD, E, BORER, J, COHEN, L. S, DALEN, J, DODGE, H. T, FRANCIS, C. K, HILLIS, D, LUDBROOK, P

“…Intravenous administration of 80 mg of recombinant tissue plasminogen activator (rt-PA, 40, 20, and 20 mg in successive hours) and streptokinase (SK, 1.5…”
Get full text

Venlafaxine in the treatment of postpartum Depression by COHEN, Lee S, VIGUERA, Adele C, BOUFFARD, Suzanne M, NONACS, Ruta M, MORABITO, Cassandra, COLLINS, Mary H, ABLON, J. Stuart

“…Although postpartum depression is a highly prevalent illness, antidepressant treatment studies of postpartum depression are sparse. Incomplete recognition and…”
Get full text

Paroxetine in Human Breast Milk and Nursing Infants by Stowe, Zachary N., Cohen, Lee S., Hostetter, Amy, Ritchie, James C., Owens, Michael J., Nemeroff, Charles B.

“…OBJECTIVE: The purpose of this study was to determine the extent of infant medication exposure through breast-feeding during maternal treatment with…”
Get full text

An analysis of 11.3 million screening tests examining the association between recall and cancer detection rates in the English NHS breast cancer screening programme by Blanks, R. G., Given-Wilson, R. M., Cohen, S. L., Patnick, J., Alison, R. J., Wallis, M. G.

“…Objective To develop methods to model the relationship between cancer detection and recall rates to inform professional standards. Methods Annual screening…”
Get full text

Correction to: An analysis of 11.3 million screening tests examining the association between recall and cancer detection rates in the English NHS breast cancer screening programme by Blanks, R. G., Given-Wilson, R. M., Cohen, S. L., Patnick, J., Alison, R. J., Wallis, M. G.

“…The original version of this article, published on 04 February 2019, unfortunately contained a mistake…”
Get full text

Role of performance metrics in breast screening imaging – where are we and where should we be? by Cohen, S.L., Blanks, R.G., Jenkins, J., Kearins, O.

“…The NHS Breast Screening Programme (NHSBSP) was started in 1988 and is a large, organised cancer screening programme. It is delivered by 80 services across…”
Get full text

Ten-year follow-up of survival and myocardial infarction in the randomized coronary artery surgery study by ALDERMAN, E. L, BOURASSA, M. G, COHEN, L. S, DAVIS, K. B, KAISER, C. G, KILLIP, T, MOCK, M. B, PETTINGER, M, ROBERTSON, T. L

“…The Coronary Artery Surgery Study (CASS) randomized 780 patients to an initial strategy of coronary surgery or medical therapy. Of medically randomized…”
Get full text

Prophylactic estrogen in recurrent postpartum affective disorder by Sichel, Deborah A., Cohen, Lee S., Robertson, Laura M., Ruttenberg, Alexandra, Rosenbaum, Jerrold F.

“…Seven women with histories of puerperal psychosis and four with histories of puerperal major depression were consecutively treated with high-dose oral estrogen…”
Get full text