Search Results - "Cohen, Kimberley A"

Interstitial Diphtheria Toxin-Epidermal Growth Factor Fusion Protein Therapy Produces Regressions of Subcutaneous Human Glioblastoma Multiforme Tumors in Athymic Nude Mice by Liu, Tie Fu, Hall, Philip D, Cohen, Kimberley A, Willingham, Mark C, Cai, Jiaozhong, Thorburn, Andrew, Frankel, Arthur E

“…Purpose: The novel fusion protein, DAB 389 EGF, composed of the catalytic and translocation domains of diphtheria toxin (DAB 389 ) fused with a His-Ala linker…”
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Diphtheria toxin-murine granulocyte-macrophage colony-stimulating factor–induced hepatotoxicity is mediated by Kupffer cells by Westcott, Marlena M, Abi-Habib, Ralph J, Cohen, Kimberley A, Willingham, Mark C, Liu, Shihui, Bugge, Thomas H, Leppla, Stephen H, Frankel, Arthur E

“…DT 388 GMCSF, a fusion toxin composed of the NH 2 -terminal region of diphtheria toxin (DT) fused to human granulocyte-macrophage colony-stimulating factor…”
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Safety evaluation of DT388IL3, a diphtheria toxin/interleukin 3 fusion protein, in the cynomolgus monkey by COHEN, Kimberley A, TIE FU LIU, CLINE, J. Mark, WAGNER, Janice D, HALL, Philip D, FRANKEL, Arthur E

“…We developed a fusion toxin, DT388IL3, consisting of the catalytic and translocation domains of diphtheria toxin (DT388) linked to interleukin 3 (IL3) for the…”
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A diphtheria toxin-epidermal growth factor fusion protein is cytotoxic to human glioblastoma multiforme cells by TIE FU LIU, COHEN, Kimberley A, RAMAGE, Jason G, WILLINGHAM, Mark C, THORBURN, Andrew M, FRANKEL, Arthur E

“…The cytotoxicity of a diphtheria toxin-human epidermal growth factor fusion protein (DAB(389)EGF) was tested against 14 human glioma cell lines. After cells…”
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Expression and purification of the recombinant diphtheria fusion toxin DT388IL3 for phase I clinical trials by Urieto, Jeffrey O, Liu, TieFu, Black, Jennifer H, Cohen, Kimberley A, Hall, Philip D, Willingham, Mark C, Pennell, Lewis K, Hogge, Donna E, Kreitman, Robert J, Frankel, Arthur E

“…A genetically engineered fusion toxin targeted to acute myeloid leukemia (AML) blasts was designed with the first 388 amino acid residues of diphtheria toxin…”
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Toxicology and Pharmacokinetics of DT388IL3, a Fusion Toxin Consisting of a Truncated Diphtheria Toxin (DT388) Linked to Human Interleukin 3 (IL3), in Cynomolgus Monkeys by Cohen, Kimberley A, LIU, Tie Fu, Cline, J Mark, Wagner, Janice D, Hall, Philip D, Frankel, Arthur E

“…The fusion toxin DT388IL3 composed of the catalytic and translocation domains of diphtheria toxin (DT388) linked to interleukin-3 (IL3) was administered to 6…”
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DAB389EGF fusion protein therapy of refractory glioblastoma multiforme by Cohen, Kimberley A, Liu, TieFu, Bissonette, Reid, Puri, Raj K, Frankel, Arthur E

“…Primary brain tumors including anaplastic astrocytomas and glioblastoma multiforme are difficult to treat because of their locally invasive nature and…”
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Diphtheria Toxin−Epidermal Growth Factor Fusion Protein and Pseudomonas Exotoxin−Interleukin 13 Fusion Protein Exert Synergistic Toxicity against Human Glioblastoma Multiforme Cells by Liu, Tie Fu, Willingham, Mark C, Tatter, Stephen B, Cohen, Kimberley A, Lowe, A. Corinne, Thorburn, Andrew, Frankel, Arthur E

“…The cytotoxicity of combinations of a diphtheria toxin−human epidermal growth factor fusion protein (DAB389EGF) and a Pseudomonas exotoxin−human interleukin 13…”
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Toxicology and Pharmacokinetics of DT 388 IL3, a Fusion Toxin Consisting of a Truncated Diphtheria Toxin (DT 388 ) Linked to Human Interleukin 3 (IL3), in Cynomolgus Monkeys by Cohen, Kimberley A, LIU, Tie Fu, Cline, J Mark, Wagner, Janice D, Hall, Philip D, Frankel, Arthur E

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Expression and purification of the recombinant diphtheria fusion toxin DT 388IL3 for phase I clinical trials by Urieto, Jeffrey O, Liu, TieFu, Black, Jennifer H, Cohen, Kimberley A, Hall, Philip D, Willingham, Mark C, Pennell, Lewis K, Hogge, Donna E, Kreitman, Robert J, Frankel, Arthur E

“…A genetically engineered fusion toxin targeted to acute myeloid leukemia (AML) blasts was designed with the first 388 amino acid residues of diphtheria toxin…”
Get full text