Search Results - "Cohen, Karen"

Systematic review of antiretroviral-associated lipodystrophy: lipoatrophy, but not central fat gain, is an antiretroviral adverse drug reaction by de Waal, Reneé, Cohen, Karen, Maartens, Gary

“…Lipoatrophy and/or central fat gain are observed frequently in patients on antiretroviral therapy (ART). Both are assumed to be antiretroviral adverse drug…”
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Adverse drug reactions in South African patients receiving bedaquiline-containing tuberculosis treatment: an evaluation of spontaneously reported cases by Jones, Jackie, Mudaly, Vanessa, Voget, Jacqueline, Naledi, Tracey, Maartens, Gary, Cohen, Karen

“…Bedaquiline was recently introduced into World Health Organization (WHO)-recommended regimens for treatment of drug resistant tuberculosis. There is limited…”
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A cross-sectional evaluation of five warfarin anticoagulation services in Uganda and South Africa by Semakula, Jerome Roy, Mouton, Johannes P, Jorgensen, Andrea, Hutchinson, Claire, Allie, Shaazia, Semakula, Lynn, French, Neil, Lamorde, Mohammed, Toh, Cheng-Hock, Blockman, Marc, Sekaggya-Wiltshire, Christine, Waitt, Catriona, Pirmohamed, Munir, Cohen, Karen

“…Warfarin is the most commonly prescribed oral anticoagulant in sub-Saharan Africa and requires ongoing monitoring. The burden of both infectious diseases and…”
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Editorial: Pharmacoeconomics in the era of health technology assessment and outcomes research to prioritize resource use, innovation and investment by Girardin, François R, Cohen, Karen, Schwenkglenks, Matthias, Durand-Zaleski, Isabelle

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Interrater agreement of two adverse drug reaction causality assessment methods: A randomised comparison of the Liverpool Adverse Drug Reaction Causality Assessment Tool and the World Health Organization-Uppsala Monitoring Centre system by Mouton, Johannes P, Mehta, Ushma, Rossiter, Dawn P, Maartens, Gary, Cohen, Karen

“…A new method to assess causality of suspected adverse drug reactions, the Liverpool Adverse Drug Reaction Causality Assessment Tool (LCAT), showed high…”
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Antiretroviral Therapy, Especially Efavirenz, Is Associated with Low Bone Mineral Density in HIV-Infected South Africans by Dave, Joel A, Cohen, Karen, Micklesfield, Lisa K, Maartens, Gary, Levitt, Naomi S

“…We determined the prevalence and correlates of low bone mineral density (BMD) in HIV-infected South Africans as there is a paucity of such data from Africa…”
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A comparison of self-report and antiretroviral detection to inform estimates of antiretroviral therapy coverage, viral load suppression and HIV incidence in Kwazulu-Natal, South Africa by Huerga, Helena, Shiferie, Fisseha, Grebe, Eduard, Giuliani, Ruggero, Farhat, Jihane Ben, Van-Cutsem, Gilles, Cohen, Karen

“…Accurately identifying individuals who are on antiretroviral therapy (ART) is important to determine ART coverage and proportion on ART who are virally…”
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Professional psychology in Canada: A survey of demographic and practice characteristics by Hunsley, John, Ronson, Ashley, Cohen, Karen R

“…The number of psychological practitioners in Canada has grown substantially over the past two decades, and numerous professional and legislative changes have…”
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Comparison of six methods to estimate adherence in an ART-naïve cohort in a resource-poor setting: which best predicts virological and resistance outcomes? by Orrell, Catherine, Cohen, Karen, Leisegang, Rory, Bangsberg, David R, Wood, Robin, Maartens, Gary

“…Incomplete adherence to antiretroviral therapy (ART) results in virologic failure and resistance. It remains unclear which adherence measure best predicts…”
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Detectable HIV-1 in semen in individuals with very low blood viral loads by Kariuki, Samuel Mundia, Selhorst, Philippe, Norman, Jennifer, Cohen, Karen, Rebe, Kevin, Williamson, Carolyn, Dorfman, Jeffrey R

“…Several reports indicate that a portion (5-10%) of men living with HIV-1 intermittently shed HIV-1 RNA into seminal plasma while on long term effective…”
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Vitamin K-dependent anticoagulant use and level of anticoagulation control in sub-Saharan Africa: protocol for a retrospective cohort study by Mwita, Julius Chacha, Damasceno, Albertino, Chillo, Pilly, Ogah, Okechukwu S, Cohen, Karen, Oyekunle, Anthony, Tefera, Endale, Francis, Joel Msafiri

“…BackgroundGiven that vitamin K-dependent anticoagulants (VKAs) will continue to be the primary anticoagulant in Africa for a long time, understanding the…”
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Making Evidence-Based Psychological Care Accessible to Canadians by Dozois, David J. A., Cohen, Karen R.

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Service-level barriers to and facilitators of access to services for the treatment of alcohol use disorder and problematic alcohol use: protocol for a scoping review by Wolfe, Dianna, Hutton, Brian, Corace, Kimberly, Chaiyakunapruk, Nathorn, Ngorsuraches, Surachat, Nochaiwong, Surapon, Presseau, Justin, Grant, Alyssa, Suschinsky, Kelly, Skidmore, Becky, Bartram, Mary, Cohen, Karen, Garner, Gord, DiGioacchino, Lisha, Pump, Andrew, Peters, Brianne, Konefal, Sarah, Porath, Amy, Thavorn, Kednapa

“…IntroductionPrior to the COVID-19 pandemic, substance use health services for treatment of alcohol use disorder and problematic alcohol use (AUD/PAU) were…”
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Severe antiretroviral-associated skin reactions in South African patients: a case series and case-control analysis by Stewart, Annemie, Lehloenya, Rannakoe, Boulle, Andrew, de Waal, Renee, Maartens, Gary, Cohen, Karen

“…Purpose Severe skin reactions may complicate combination antiretroviral therapy (cART). Nevirapine is known to be associated with severe skin reactions, but…”
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A genome-wide association study of plasma concentrations of warfarin enantiomers and metabolites in sub-Saharan black-African patients by Asiimwe, Innocent G., Blockman, Marc, Cohen, Karen, Cupido, Clint, Hutchinson, Claire, Jacobson, Barry, Lamorde, Mohammed, Morgan, Jennie, Mouton, Johannes P., Nakagaayi, Doreen, Okello, Emmy, Schapkaitz, Elise, Sekaggya-Wiltshire, Christine, Semakula, Jerome R., Waitt, Catriona, Zhang, Eunice J., Jorgensen, Andrea L., Pirmohamed, Munir

“…Diversity in pharmacogenomic studies is poor, especially in relation to the inclusion of black African patients. Lack of funding and difficulties in…”
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Routine data underestimates the incidence of first-line antiretroviral drug discontinuations due to adverse drug reactions: Observational study in two South African cohorts by de Waal, Reneé, Cohen, Karen, Boulle, Andrew, Fox, Matthew P, Maartens, Gary, Igumbor, Ehimario U, Davies, Mary-Ann

“…Estimating the incidence of antiretroviral discontinuations due to adverse drug reactions (ADRs) is important to inform antiretroviral treatment (ART) regimen…”
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Serious adverse drug reactions at two children's hospitals in South Africa by Mouton, Johannes P, Fortuin-de Smidt, Melony C, Jobanputra, Nicole, Mehta, Ushma, Stewart, Annemie, de Waal, Reneé, Technau, Karl-Günter, Argent, Andrew, Kroon, Max, Scott, Christiaan, Cohen, Karen

“…The high HIV prevalence in South Africa may potentially be shaping the local adverse drug reaction (ADR) burden. We aimed to describe the prevalence and…”
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Serious adverse drug reactions in sub‐Saharan Africa in the era of antiretroviral treatment: A systematic review by Mouton, Johannes P., Jobanputra, Nicole, Tatz, Gayle, Cohen, Karen

“…We aimed to summarize and describe the burden of serious adverse drug reactions (ADRs) in sub‐Saharan Africa (SSA) in the era of antiretroviral therapy. We…”
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Stable warfarin dose prediction in sub‐Saharan African patients: A machine‐learning approach and external validation of a clinical dose–initiation algorithm by Asiimwe, Innocent G., Blockman, Marc, Cohen, Karen, Cupido, Clint, Hutchinson, Claire, Jacobson, Barry, Lamorde, Mohammed, Morgan, Jennie, Mouton, Johannes P., Nakagaayi, Doreen, Okello, Emmy, Schapkaitz, Elise, Sekaggya‐Wiltshire, Christine, Semakula, Jerome R., Waitt, Catriona, Zhang, Eunice J., Jorgensen, Andrea L., Pirmohamed, Munir

“…Warfarin remains the most widely prescribed oral anticoagulant in sub‐Saharan Africa. However, because of its narrow therapeutic index, dosing can be…”
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Severe efavirenz associated neurotoxicity: A retrospective cohort study by Arnab, Priyadarshini, Croxford, Roland, Scott, Janet, Perumal, Sameshan, Mohammed, Zahraa, Wiesner, Lubbe, Cohen, Karen, Wasserman, Sean

“…Abstract only…”
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