Search Results - "Cohen, Isaac V."

Analysis of postmarketing safety data for proton-pump inhibitors reveals increased propensity for renal injury, electrolyte abnormalities, and nephrolithiasis by Makunts, Tigran, Cohen, Isaac V., Awdishu, Linda, Abagyan, Ruben

“…Proton pump inhibitors, PPIs, are widely prescribed and sold globally. Although initially intended for time-limited treatment of acute disorders, such as…”
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Concomitant drugs associated with increased mortality for MDMA users reported in a drug safety surveillance database by Cohen, Isaac V., Makunts, Tigran, Abagyan, Ruben, Thomas, Kelan

“…3,4-Methylenedioxymethamphetamine (MDMA) is currently being evaluated by the Food and Drug Administration (FDA) for the treatment of post-traumatic stress…”
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Myocarditis occurrence with cancer immunotherapy across indications in clinical trial and post-marketing data by Makunts, Tigran, Saunders, Ila M., Cohen, Isaac V., Li, Mengxing, Moumedjian, Talar, Issa, Masara A., Burkhart, Keith, Lee, Peter, Patel, Sandip Pravin, Abagyan, Ruben

“…Antibodies targeting the PD-1, PD-L1, and CTLA-4 immune checkpoint axis have been used in a variety of tumor types. They achieve anti-tumor activity through…”
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Population scale data reveals the antidepressant effects of ketamine and other therapeutics approved for non-psychiatric indications by Cohen, Isaac V., Makunts, Tigran, Atayee, Rabia, Abagyan, Ruben

“…Current therapeutic approaches to depression fail for millions of patients due to lag in clinical response and non-adherence. Here we provide new support for…”
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Population scale retrospective analysis reveals distinctive antidepressant and anxiolytic effects of diclofenac, ketoprofen and naproxen in patients with pain by Makunts, Tigran, Cohen, Isaac V, Lee, Kelly C, Abagyan, Ruben

“…Currently approved monoamine modulating antidepressant and anxiolytic pharmaceutics fail in over one third of patients due to delayed and variable therapeutic…”
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An unsupervised learning approach to identify novel signatures of health and disease from multimodal data by Shomorony, Ilan, Cirulli, Elizabeth T, Huang, Lei, Napier, Lori A, Heister, Robyn R, Hicks, Michael, Cohen, Isaac V, Yu, Hung-Chun, Swisher, Christine Leon, Schenker-Ahmed, Natalie M, Li, Weizhong, Nelson, Karen E, Brar, Pamila, Kahn, Andrew M, Spector, Timothy D, Caskey, C Thomas, Venter, J Craig, Karow, David S, Kirkness, Ewen F, Shah, Naisha

“…Modern medicine is rapidly moving towards a data-driven paradigm based on comprehensive multimodal health assessments. Integrated analysis of data from…”
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Publisher Correction: Population scale data reveals the antidepressant effects of ketamine and other therapeutics approved for non-psychiatric indications by Cohen, Isaac V., Makunts, Tigran, Atayee, Rabia, Abagyan, Ruben

“…A correction to this article has been published and is linked from the HTML version of this paper. The error has not been fixed in the paper…”
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Acetaminophen (Paracetamol) Use Modifies the Sulfation of Sex Hormones by Cohen, Isaac V., Cirulli, Elizabeth T., Mitchell, Matthew W., Jonsson, Thomas J., Yu, James, Shah, Naisha, Spector, Tim D., Guo, Lining, Venter, J. Craig, Telenti, Amalio

“…Acetaminophen (paracetamol) is one of the most common medications used for management of pain in the world. There is lack of consensus about the mechanism of…”
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Precision medicine integrating whole-genome sequencing, comprehensive metabolomics, and advanced imaging by Hou, Ying-Chen Claire, Yu, Hung-Chun, Martin, Rick, Cirulli, Elizabeth T., Schenker-Ahmed, Natalie M., Hicks, Michael, Cohen, Isaac V., Jönsson, Thomas J., Heister, Robyn, Napier, Lori, Swisher, Christine Leon, Dominguez, Saints, Tang, Haibao, Li, Weizhong, Perkins, Bradley A., Barea, Jaime, Rybak, Christina, Smith, Emily, Duchicela, Keegan, Doney, Michael, Brar, Pamila, Hernandez, Nathaniel, Kirkness, Ewen F., Kahn, Andrew M., Venter, J. Craig, Karow, David S., Caskey, C. Thomas

“…Genome sequencing has established clinical utility for rare disease diagnosis. While increasing numbers of individuals have undergone elective genome…”
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Cardiac adverse events associated with chloroquine and hydroxychloroquine exposure in 20 years of drug safety surveillance reports by Cohen, Isaac V., Makunts, Tigran, Moumedjian, Talar, Issa, Masara A., Abagyan, Ruben

“…Chloroquine (CQ) and hydroxychloroquine (HCQ) are on the World Health Organization’s List of Essential Medications for treating non-resistant malaria,…”
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