Search Results - "Cohen, Hagit"

Is PTSD-Phenotype Associated with HPA-Axis Sensitivity? Feedback Inhibition and Other Modulating Factors of Glucocorticoid Signaling Dynamics by Danan, Dor, Todder, Doron, Zohar, Joseph, Cohen, Hagit

“…Previously, we found that basal corticosterone pulsatility significantly impacts the vulnerability for developing post-traumatic stress disorder (PTSD). Rats…”
Get full text

The Role of Microglia in the (Mal)adaptive Response to Traumatic Experience in an Animal Model of PTSD by Nahum, Kesem, Todder, Doron, Zohar, Joseph, Cohen, Hagit

“…The present study investigates whether predator scent-stress (PSS) shifts the microglia from a quiescent to a chronically activated state and whether…”
Get full text

Is PTSD-Phenotype Associated with HPA-Axis Sensitivity?: The Endocannabinoid System in Modulating Stress Response in Rats by Danan, Dor, Todder, Doron, Zohar, Joseph, Cohen, Hagit

“…Endocannabinoids play a role in adaptation to stress and regulate the release of glucocorticoids in stressed and unstressed conditions. We recently found that…”
Get full text

Expression profiling associates blood and brain glucocorticoid receptor signaling with trauma-related individual differences in both sexes by Daskalakis, Nikolaos P., Cohen, Hagit, Cai, Guiqing, Buxbaum, Joseph D., Yehuda, Rachel

“…Significance Because posttraumatic stress disorder (PTSD) occurs in a subset of trauma-exposed persons, expression profiling in the context of an animal model…”
Get full text

A prospective clinical cohort-based study of the prevalence of OCD, obsessive compulsive and related disorders, and tics in families of patients with OCD by Carmi, Lior, Brakoulias, Vlasios, Arush, Oded Ben, Cohen, Hagit, Zohar, Joseph

“…The lifetime prevalence of obsessive - compulsive disorder (OCD) is currently estimated at 2 - 3% and the prevalence in first-degree family members is…”
Get full text

New translational perspectives for blood-based biomarkers of PTSD: From glucocorticoid to immune mediators of stress susceptibility by Daskalakis, Nikolaos P., Cohen, Hagit, Nievergelt, Caroline M., Baker, Dewleen G., Buxbaum, Joseph D., Russo, Scott J., Yehuda, Rachel

“…Although biological systems have evolved to promote stress-resilience, there is variation in stress-responses. Understanding the biological basis of such…”
Get full text

Reduction in endogenous cardiac steroids protects the brain from oxidative stress in a mouse model of mania induced by amphetamine by Hodes, Anastasia, Lifschytz, Tzuri, Rosen, Haim, Cohen Ben-Ami, Hagit, Lichtstein, David

“…[Display omitted] •AMPH induces hyperactivity and brain oxidative stress in mice.•Reduction in endogenous cardiac steroids (CS) inhibited AMPH-induced…”
Get full text

Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood by Kipnis, Jonathan, Schwartz, Michal, Ziv, Yaniv, Ron, Noga, Butovsky, Oleg, Landa, Gennady, Sudai, Einav, Greenberg, Nadav, Cohen, Hagit

“…Neurogenesis is known to take place in the adult brain. This work identifies T lymphocytes and microglia as being important to the maintenance of hippocampal…”
Get full text

High dose hydrocortisone immediately after trauma may alter the trajectory of PTSD: Interplay between clinical and animal studies by Zohar, Joseph, Yahalom, Hila, Kozlovsky, Nitsan, Cwikel-Hamzany, Shlomit, Matar, Michael A, Kaplan, Zeev, Yehuda, Rachel, Cohen, Hagit

“…Abstract High-dose corticosteroids have been reported to reduce symptoms of acute stress and post-traumatic stress in polytrauma patients and in animal…”
Get full text

Glatiramer Acetate Fights against Alzheimer's Disease by Inducing Dendritic-Like Microglia Expressing Insulin-Like Growth Factor 1 by Butovsky, Oleg, Koronyo-Hamaoui, Maya, Kunis, Gilad, Ophir, Eran, Landa, Gennady, Cohen, Hagit, Schwartz, Michal

“…Alzheimer's disease (AD) is characterized by plaque formation, neuronal loss, and cognitive decline. The functions of the local and systemic immune response in…”
Get full text

Gender differences in animal models of posttraumatic stress disorder by Cohen, Hagit, Yehuda, Rachel

“…Epidemiological studies report higher prevalence rates of stress-related disorders such as acute stress disorder and post-traumatic stress disorder (PTSD) in…”
Get full text

Ouabain improves functional recovery following traumatic brain injury by Dvela-Levitt, Moran, Ami, Hagit Cohen-Ben, Rosen, Haim, Shohami, Esther, Lichtstein, David

“…The cardiac steroid ouabain binds to Na(+), K(+)-ATPase and inhibits its activity. Administration of the compound to animals and humans causes an increase in…”
Get more information

Promoter methylation of the glucocorticoid receptor following trauma may be associated with subsequent development of PTSD by Carmi, Lior, Zohar, Joseph, Juven-Wetzler, Alzbeta, Desarnaud, Frank, Makotkine, Louri, Bierer, Linda M., Cohen, Hagit, Yehuda, Rachel

“…The ability to identify persons at elevated risk for post-traumatic stress disorder (PTSD) soon after exposure to trauma, could aid clinical decision-making…”
Get full text

Saliva metabolome alterations after acute stress by Morgan, Liat, Birkler, Rune Isak Dupont, Shaham-Niv, Shira, Dong, Yonghui, Wachsman, Tal, Carmi, Lior, Yakobson, Boris, Adler-Abramovich, Lihi, Cohen, Hagit, Zohar, Joseph, Bateson, Melissa, Gazit, Ehud

“…Major stress has systemic effects on the body that can have adverse consequences for physical and mental health. However, the molecular basis of these damaging…”
Get full text

Chronic exposure to stress predisposes to higher autoimmune susceptibility in C57BL/6 mice: Glucocorticoids as a double‐edged sword by Harpaz, Idan, Abutbul, Shai, Nemirovsky, Anna, Gal, Ram, Cohen, Hagit, Monsonego, Alon

“…Stress activates the hypothalamic‐pituitary‐adrenocortical axis to promote the release of corticosterone (CORT), which consequently suppresses pathogenic…”
Get full text

MDMA treatment paired with a trauma-cue promotes adaptive stress responses in a translational model of PTSD in rats by Arluk, Shira, Matar, Michael A., Carmi, Lior, Arbel, Oded, Zohar, Joseph, Todder, Doron, Cohen, Hagit

“…MDMA (3,4-methylenedioxymethamphetamine), a synthetic ring-substituted amphetamine, combined with psychotherapy has demonstrated efficacy for the treatment of…”
Get full text

Heat-Stress Preconditioning Attenuates Behavioral Responses to Psychological Stress: The Role of HSP-70 in Modulating Stress Responses by Belity, Tal, Horowitz, Michal, Hoffman, Jay R, Epstein, Yoram, Bruchim, Yaron, Todder, Doron, Cohen, Hagit

“…Exposure to high ambient temperature is a stressor that influences both biological and behavioral functions and has been previously shown to have an extensive…”
Get full text

T Cell Deficiency Leads to Cognitive Dysfunction: Implications for Therapeutic Vaccination for Schizophrenia and Other Psychiatric Conditions by Kipnis, Jonathan, Cohen, Hagit, Cardon, Michal, Ziv, Yaniv, Schwartz, Michal, Sela, Michael

“…The effects of the adaptive immune system on the cognitive performance and abnormal behaviors seen in mental disorders such as schizophrenia have never been…”
Get full text

Water is the Taste of Life – The Contribution of Metacognitive Guidance to Drinking-related Nutritional Literacy by Cohen Hagit, Zion Michal

“…This study examined the contribution of metacognitive guidance to the development of drinking-related nutritional literacy(DNL). Metacognitive awareness…”
Get full text

Beyond the HPA-axis: The role of the gonadal steroid hormone receptors in modulating stress-related responses in an animal model of PTSD by Fenchel, Daphna, Levkovitz, Yechiel, Vainer, Ella, Kaplan, Zeev, Zohar, Joseph, Cohen, Hagit

“…Abstract The hypothalamic–pituitary–adrenal (HPA) axis, which plays a major role in the response to stress, and the hypothalamic–pituitary–gonadal (HPG) axis…”
Get full text