Search Results - "Cohane, Kenya"

Identification of novel virus-specific antigens by CD4+ and CD8+ T cells from asymptomatic HSV-2 seropositive and seronegative donors by Long, Deborah, Skoberne, Mojca, Gierahn, Todd M, Larson, Shane, Price, Jessica A, Clemens, Veronica, Baccari, Amy E, Cohane, Kenya P, Garvie, Danielle, Siber, George R, Flechtner, Jessica B

“…Abstract Reactivation of latent herpes simplex virus 2 (HSV-2) infections can be characterized by episodic recurrent genital lesions and/or viral shedding. We…”
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A Phase 1 Study in Healthy Subjects to Evaluate the Safety and Pharmacokinetics of a Human Monoclonal Antibody (S315) Against Diphtheria Toxin by Sullivan-Bólyai, John Z, Allen, Larry B, Cannon, Rebecca, Cohane, Kenya P, Dunzo, Elise, Goldwater, Ronald, StCyr, Kathleen, Wang, Yang, Klempner, Mark S

“…Diphtheria is a recurrent threat with endemic still occurs in many parts of the world. The standard of care is horse serum-derived diphtheria antitoxin (eDAT),…”
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New Flow-Based, Multiplex Assays Allow Simultaneous Quantification of 13 Soluble Factors Related to Macrophage/Microglia or B Cell Functions by Sun, Binggang, Rughwani, Priyanka, Cohane, Kenya, Ji, Shaoquan, Taylor, Peggy, Jiang, Weiping

“…Immune responses are mediated by innate immune cells (e.g., macrophages) and subsequently, adaptive immune cells (e.g., B cells). Macrophages secrete an array…”
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High-throughput proteomic screening identifies Chlamydia trachomatis antigens that are capable of eliciting T cell and antibody responses that provide protection against vaginal challenge by Picard, Michele D, Cohane, Kenya Prince, Gierahn, Todd M, Higgins, Darren E, Flechtner, Jessica Baker

“…Highlights ► Chlamydia proteomic screen yielded T cell antigens for vaccine development. ► Screening of peripheral T cells can identify T cell antigens…”
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Resolution of Chlamydia trachomatis Infection Is Associated with a Distinct T Cell Response Profile by Picard, Michele D, Bodmer, Jean-Luc, Gierahn, Todd M, Lee, Alexander, Price, Jessica, Cohane, Kenya, Clemens, Veronica, DeVault, Victoria L, Gurok, Galina, Kohberger, Robert, Higgins, Darren E, Siber, George R, Flechtner, Jessica Baker, Geisler, William M

“…Chlamydia trachomatis is the causative agent of the most frequently reported bacterial sexually transmitted infection, the total burden of which is…”
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High-throughput proteomic screening identifiesChlamydia trachomatisantigens that are capable of eliciting T cell and antibody responses that provide protection against vaginal challenge by Picard, Michele D, Cohane, Kenya Prince, Gierahn, Todd M, Higgins, Darren E, Flechtner, Jessica Baker

“…Highlights *Chlamydiaproteomic screen yielded T cell antigens for vaccine development. * Screening of peripheral T cells can identify T cell antigens…”
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High-Affinity Interactions between Peptides and Heat Shock Protein 70 Augment CD8+ T Lymphocyte Immune Responses by Flechtner, Jessica B, Cohane, Kenya Prince, Mehta, Sunil, Slusarewicz, Paul, Leonard, Alexis Kays, Barber, Brian H, Levey, Daniel L, Andjelic, Sofija

“…Exogenously delivered antigenic peptides complexed to heat shock proteins (HSPs) are able to enter the endogenous Ag-processing pathway and prime CD8+ CTL. It…”
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High-Affinity Interactions between Peptides and Heat Shock Protein 70 Augment CD8 super(+) T Lymphocyte Immune Responses by Flechtner, Jessica B, Cohane, Kenya Prince, Mehta, Sunil, Slusarewicz, Paul, Leonard, Alexis Kays, Barber, Brian H, Levey, Daniel L, Andjelic, Sofija

“…Exogenously delivered antigenic peptides complexed to heat shock proteins (HSPs) are able to enter the endogenous Ag-processing pathway and prime CD8 super(+)…”
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