Search Results - "Coghlan, J G"

Prevalence and outcome in systemic sclerosis associated pulmonary arterial hypertension: application of a registry approach by Mukerjee, D, St George, D, Coleiro, B, Knight, C, Denton, C P, Davar, J, Black, C M, Coghlan, J G

“…Objective: To determine the prevalence of systemic sclerosis associated pulmonary arterial hypertension (SScPAH), evaluate outcome, and identify predictors of…”
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Prognostic and aetiological factors in chronic thromboembolic pulmonary hypertension by Condliffe, R, Kiely, D. G, Gibbs, J. S. R, Corris, P. A, Peacock, A. J, Jenkins, D. P, Goldsmith, K, Coghlan, J. G, Pepke-Zaba, J

“…Several prognostic variables have previously been identified in patients with chronic thromboembolic pulmonary hypertension (CTEPH). Specific medical…”
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Systemic sclerosis associated pulmonary hypertension: improved survival in the current era by Williams, M H, Das, C, Handler, C E, Akram, M R, Davar, J, Denton, C P, Smith, C J, Black, C M, Coghlan, J G

“…Objectives: To measure survival, haemodynamic function and functional class in patients with systemic sclerosis associated pulmonary arterial hypertension…”
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Improved survival in systemic sclerosis is associated with better ascertainment of internal organ disease: a retrospective cohort study by Nihtyanova, S.I., Tang, E.C., Coghlan, J.G., Wells, A.U., Black, C.M., Denton, C.P.

“…Background: Systemic sclerosis (SSc) has high mortality and morbidity. Current management focuses on early detection and treatment of organ-based…”
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Echocardiography and pulmonary function as screening tests for pulmonary arterial hypertension in systemic sclerosis by Mukerjee, D., St. George, D., Knight, C., Davar, J., Wells, A. U., Du Bois, R. M., Black, C. M., Coghlan, J. G.

“…Objective. A prospective study to evaluate echocardiography and gas transfer (DLCO) by comparison with cardiac catheterization in discriminating between…”
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A new era in the management of pulmonary arterial hypertension related to scleroderma: endothelin receptor antagonism by Hachulla, E, Coghlan, J G

“…Evidence suggests that endothelin may have a fundamental role in scleroderma pathogenesis, including pulmonary arterial hypertension (PAH)—a leading cause of…”
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Angiographically proven coronary artery disease in scleroderma by AKRAM, M. R, HANDLER, C. E, WILLIAMS, M, CARULLI, M. T, ANDRON, M, BLACK, C. M, DENTON, C. P, COGHLAN, J. G

“…It has been suggested that macrovascular disease is more common in patients with scleroderma (SSc). We investigated the prevalence of coronary artery disease…”
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Aggressive combination therapy for treatment of systemic sclerosis-associated pulmonary hypertension by Coghlan, JG, Denton, Christopher P.

“…Pulmonary arterial hypertension is an important complication of systemic sclerosis with high mortality but should be regarded as a treatable manifestation of…”
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Safety and feasibility audit of a home-based drug-transitioning approach for patients with pulmonary arterial hypertension: an observational study by Dawson, A, Reddecliffe, S, Coghlan, C, Schreiber, BE, Coghlan, JG

“…Background: Newer endothelin receptor antagonists (ERAs) used to treat patients with pulmonary arterial hypertension (PAH) are associated with fewer drug–drug…”
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Can CCL2 serum levels be used in risk stratification or to monitor treatment response in systemic sclerosis? by Carulli, M T, Handler, C, Coghlan, J G, Black, C M, Denton, C P

“…The chemokine CCL2 has been consistently found to be up-regulated in systemic sclerosis. To explore the potential value of serum CCL2 measurement in disease…”
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Significance of plasma N-terminal pro-brain natriuretic peptide in patients with systemic sclerosis-related pulmonary arterial hypertension by Mukerjee, D, Yap, L.B, Holmes, A.M, Nair, D, Ayrton, P, Black, C.M, Coghlan, J.G

“…Objectives: A single centre pilot study to investigate the role of the plasma N-terminal pro-brain natriuretic peptide (N-T proBNP) assay to risk stratify…”
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Combined Pulmonary Fibrosis and Emphysema in Scleroderma‐Related Lung Disease Has a Major Confounding Effect on Lung Physiology and Screening for Pulmonary Hypertension by Antoniou, K. M., Margaritopoulos, G. A., Goh, N. S., Karagiannis, K., Desai, S. R., Nicholson, A. G., Siafakas, N. M., Coghlan, J. G., Denton, C. P., Hansell, D. M., Wells, A. U.

“…Objective To assess the prevalence of combined pulmonary fibrosis and emphysema (CPFE) in systemic sclerosis (SSc) patients with interstitial lung disease…”
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The heart and pulmonary vasculature in scleroderma: clinical features and pathobiology by Coghlan, J G, Mukerjee, Dev

“…For nearly 50 years there have been concerns that scleroderma affects the heart. The two main mechanisms that are thought to be involved are; a fibrotic…”
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Connective tissue associated pulmonary arterial hypertension by Coghlan, J G, Handler, C

“…The number of publications in the field of pulmonary hypertension has increased exponentially over the past 10 years. As a consequence our understanding of the…”
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UK resources in the care of adults with Down’s syndrome by Marder, Liz, Coghlan, J G

“…The UK Down's Syndrome Association has therefore recently developed a health book for adults with Down's syndrome to help guide practitioners through the…”
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The myth of pulmonary Raynaud’s phenomenon: the contribution of pulmonary arterial vasospasm in patients with systemic sclerosis related pulmonary arterial hypertension by Mukerjee, D, Yap, L B, Ong, V, Denton, C P, Howells, K, Black, C M, Coghlan, J G

“…Objective: To investigate the contribution of cold induced pulmonary vasospasm by peripheral and central cold stimulus in exacerbating pulmonary arterial…”
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Screening for pulmonary hypertension: reply by Coghlan, J G

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Real-time myocardial contrast dobutamine stress echocardiography in coronary stenosis by Roberts, Elved B., Schafer, Frank, Akhtar, Wahid, Patel, Devan, Evans, Tom R., Coghlan, J.G., Lipkin, David P., Davar, Joseph I.

“…Simultaneous wall motion and myocardial perfusion analysis could offer advantages over either method alone. Diagnostic utility of combining these parameters…”
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Scleroderma and breast implants by Hong, C, Sangle, S R, Coghlan, J G, D'Cruz, D P

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Campylobacter pylori and recurrence of duodenal ulcers--a 12-month follow-up study by Coghlan, J G, Gilligan, D, Humphries, H, McKenna, D, Dooley, C, Sweeney, E, Keane, C, O'Morain, C

“…In 39 patients with endoscopically healed duodenal ulcers repeat endoscopy and two antral biopsies after 1 year showed a relapse rate of 59%. Only…”
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