Search Results - "Coghe, G."

Evolution of teriflunomide use in multiple sclerosis: A real-world experience by Lorefice, L., Pilotto, S., Fenu, G., Cimino, P., Firinu, D., Frau, J., Murgia, F., Coghe, G., Cocco, E.

“…The present study aims to describe the evolution of teriflunomide use for multiple sclerosis (MS) in the clinical setting, in particular for naïve patients and…”
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Performance in daily activities, cognitive impairment and perception in multiple sclerosis patients and their caregivers by Fenu, G, Fronza, M, Lorefice, L, Arru, M, Coghe, G, Frau, J, Marrosu, M G, Cocco, E

“…The relationship between cognitive assessment results in multiple sclerosis (MS) and performance in daily activities (DAs) remains unclear. Our study aimed to…”
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‘Timed up and go’ and brain atrophy: a preliminary MRI study to assess functional mobility performance in multiple sclerosis by Lorefice, Lorena, Coghe, G., Fenu, G., Porta, M., Pilloni, G., Frau, J., Corona, F., Sechi, V., Barracciu, M. A., Marrosu, M. G., Pau, M., Cocco, E.

“…Motor and cognitive disabilities are related to brain atrophy in multiple sclerosis (MS). ‘Timed up and go’ (TUG) has been recently tested in MS as functional…”
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Multidimensional frailty and its association with quality of life and disability: A cross-sectional study in people with multiple sclerosis by Frau, J, Mulasso, A, Coghe, G, Melis, M, Beratto, L, Cuomo, S, Lorefice, L, Fenu, G, Cocco, E

“…People with multiple sclerosis (pwMS) have a high risk of frailty. We aim to evaluate frailty using the Tilburg frailty indicator (TFI), a multidimensional…”
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Walking improvements with nabiximols in patients with multiple sclerosis by Coghe, G., Pau, M., Corona, F., Frau, J., Lorefice, L., Fenu, G., Spinicci, G., Mamusa, E., Musu, L., Massole, S., Massa, R., Marrosu, M. G., Cocco, E.

“…Recently, nabiximols was approved as a treatment in MS spasticity. Data leading to approval and clinical use of nabiximols, although widely recognised, are…”
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Cognition in multiple sclerosis: Between cognitive reserve and brain volume by Fenu, G., Lorefice, L., Arru, M., Sechi, V., Loi, L., Contu, F., Cabras, F., Coghe, G., Frau, J., Fronza, M., Sbrescia, G., Lai, V., Boi, M., Mallus, S., Murru, S., Porcu, A., Barracciu, M.A., Marrosu, M.G., Cocco, E.

“…Several correlations between cognitive impairment (CI), radiologic markers and cognitive reserve (CR) have been documented in MS. To evaluate correlation…”
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Pregnancy planning and outcomes in patients with multiple sclerosis after mitoxantrone therapy: a monocentre assessment by Frau, J., Coghe, G., Casanova, P., Sardu, C., Lorefice, L., Fenu, G., Marrosu, M. G., Cocco, E.

“…Background and purpose Patients with multiple sclerosis (MS) have many pregnancy‐related doubts and fears. Careful counselling is thus important. Mitoxantrone…”
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The impact of deep grey matter volume on cognition in multiple sclerosis by Lorefice, L., Carta, E., Frau, J., Contu, F., Casaglia, E., Coghe, G., Barracciu, M.A., Cocco, E., Fenu, G.

“…Cognitive dysfunctions are very frequent in people living with multiple sclerosis (MS). Several studies have previously indicated grey matter (GM) atrophy as…”
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Mycobacterium avium subsp. paratuberculosis and multiple sclerosis in Sardinian patients: epidemiology and clinical features by Frau, J, Cossu, D, Coghe, G, Lorefice, L, Fenu, G, Melis, M, Paccagnini, D, Sardu, C, Murru, MR, Tranquilli, S, Marrosu, MG, Sechi, LA, Cocco, E

“…Background: Mycobacterium avium subspecies paratuberculosis (MAP) is an infectious factor recently found in association with multiple sclerosis (MS) in…”
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Attitude towards physical activity in patients with multiple sclerosis: a cohort study by Frau, Jessica, Coghe, G., Lorefice, L., Fenu, G., Cadeddu, B., Marrosu, M. G., Cocco, E.

“…Multiple sclerosis (MS) is a long-lasting neurological disease with onset in young adult age. Patients with MS are less active than healthy people, and their…”
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Event-related potentials and deep grey matter atrophy in multiple sclerosis: Exploring the possible associations with cognition by Lorefice, L., Fenu, G., Mammoliti, R., Carta, E., Sechi, V., Frau, J., Coghe, G., Canalis, L., Barracciu, MA, Marrosu, G., Marrosu, MG, Cocco, E.

“…•We explored the relationship between event-related potentials, deep grey matter atrophy and cognition in MS.•Cortex volume emerged as the most significant…”
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Assessing the burden of vascular risk factors on brain atrophy in multiple sclerosis: A case- control MRI study by Lorefice, L., Frau, J., Coghe, G., Pitzalis, R., Gessa, I., Contu, F., Barracciu, M.A., Marrosu, M.G., Cocco, E., Fenu, G.

“…•Vascular comorbidities are very common in general population as in MS patients.•Our results indicated vascular comorbidities as negative prognostic factors…”
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Bipolar disorders and deep grey matter in multiple sclerosis: A preliminary quantitative MRI study by Lorefice, L., Fenu, G., Carta, E., Frau, J., Coghe, G., Contu, F., Barracciu, M.A., Carta, M.G., Cocco, E.

“…•Bipolar disorder (BD) is frequently observed in multiple sclerosis (MS).•Largely unexplored is the brain damage related to BD in MS.•We found smaller nucleus…”
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A genetic association study of two genes linked to neurodegeneration in a Sardinian multiple sclerosis population: The TARDBP Ala382Thr mutation and C9orf72 expansion by Lorefice, L, Murru, MR, Fenu, G, Corongiu, D, Frau, J, Cuccu, S, Coghe, G.C, Tranquilli, S, Cocco, E, Marrosu, M.G

“…Abstract Multiple sclerosis (MS) is a chronic disease of the central nervous system characterized by inflammation and accompanied and followed by…”
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Progressive multiple sclerosis and mood disorders by Lorefice, Lorena, Fenu, G., Trincas, G., Moro, M. F., Frau, J., Coghe, G. C., Cocco, E., Marrosu, M. G., Carta, M. G.

“…Mood disorders are very common among multiple sclerosis (MS) patients, but their frequency in patients with progressive course (PMS) has not been adequately…”
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Combining HLA-DRB1-DQB1 and Mycobacterium Avium Subspecies Paratubercolosis (MAP) antibodies in Sardinian multiple sclerosis patients: associated or independent risk factors? by Frau, J, Cossu, D, Sardu, C, Mameli, G, Coghe, G, Lorefice, L, Fenu, G, Tranquilli, S, Sechi, L A, Marrosu, M G, Cocco, E

“…Amongst Sardinians the human leukocyte antigen (HLA) DRB1-DQB1 haplotypes *15:02-*06:01, *16:01-*05:02, *14:01-4-*05:03 are protective for multiple sclerosis…”
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Adult brain volume in multiple sclerosis: The impact of paediatric onset by Fenu, G., Lorefice, L., Loi, L., Sechi, V., Contu, F., Coghe, G., Frau, J., Spinicci, G., Barracciu, M.A., Marrosu, M.G., Cocco, E.

“…Paediatric onset multiple sclerosis (POMS) is associated with reduced brain and deep grey matter volume in comparison with that in healthy controls and…”
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Diagnostic tools for assessment of urinary dysfunction in MS patients without urinary disturbances by Ghezzi, A., Mutta, E., Bianchi, F., Bonavita, S., Buttari, F., Caramma, A., Cavarretta, R., Centonze, D., Coghe, G. C., Coniglio, G., Del Carro, U., Ferrò, M. T., Marrosu, M. G., Patti, F., Rovaris, M., Sparaco, M., Simone, I., Tortorella, C., Bergamaschi, R.

“…Many guidelines are available for the management of lower urinary tract symptoms (LUTSs) in multiple sclerosis (MS) patients, but no agreement exists on the…”
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Switching from natalizumab to fingolimod by Melis, M, Cocco, E, Sardu, C, Frau, J, Lorefice, L, Coghe, G, Fenu, G, Marrosu, M.G

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A genetic study of the FMR1 gene in a Sardinian multiple sclerosis population by Lorefice, L., Tranquilli, S., Fenu, G., Murru, M. R., Frau, J., Rolesu, M., Coghe, G. C., Marrosu, F., Marrosu, M. G., Cocco, E.

“…Multiple sclerosis (MS) is a complex autoimmune disease originated from the interplay between genetic and environmental factors. An overlap of clinical and…”
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