Search Results - "Coffman, Abigail"
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Tissue engineering of human hair follicles using a biomimetic developmental approach
Published in Nature communications (13-12-2018)“…Human skin constructs (HSCs) have the potential to provide an effective therapy for patients with significant skin injuries and to enable human-relevant drug…”
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A Bisphosphonate With a Low Hydroxyapatite Binding Affinity Prevents Bone Loss in Mice After Ovariectomy and Reverses Rapidly With Treatment Cessation
Published in JBMR plus (01-04-2021)“…ABSTRACT Bisphosphonates (BPs) are a mainstay of osteoporosis treatment; however, concerns about bone health based on oversuppression of remodeling remain…”
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Human Skin Constructs with Spatially Controlled Vasculature Using Primary and iPSC-Derived Endothelial Cells
Published in Advanced healthcare materials (01-07-2016)“…Vascularization of engineered human skin constructs is crucial for recapitulation of systemic drug delivery and for their long‐term survival, functionality,…”
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Restoration of Bone Material and Microstructural Properties after Long-Term Remodeling Suppression
Published 01-01-2021“…Anti-resorptive drugs, principally bisphosphonates (BPs), are the mainstay of osteoporosis treatment. They work by inhibiting bone resorption/remodeling, thus…”
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Dissertation -
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Design and Characterization of Compact, Programmable, Multistranded Nonimmunostimulatory Nucleic Acid Nanoparticles Suitable for Biomedical Applications
Published in Biochemistry (Easton) (06-02-2024)“…We report a thorough investigation of the role of single-stranded thymidine (ssT) linkers in the stability and flexibility of minimal, multistranded DNA…”
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Journal Article