Search Results - "Coffey, P."

Wireless, intraoral hybrid electronics for real-time quantification of sodium intake toward hypertension management by Lee, Yongkuk, Howe, Connor, Mishra, Saswat, Lee, Dong Sup, Mahmood, Musa, Piper, Matthew, Kim, Youngbin, Tieu, Katie, Byun, Hun-Soo, Coffey, James P., Shayan, Mahdis, Chun, Youngjae, Costanzo, Richard M., Yeo, Woon-Hong

“…Recent wearable devices offer portable monitoring of biopotentials, heart rate, or physical activity, allowing for active management of human health and…”
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Selective, novel spleen tyrosine kinase (Syk) inhibitors suppress chronic lymphocytic leukemia B-cell activation and migration by Hoellenriegel, J, Coffey, G P, Sinha, U, Pandey, A, Sivina, M, Ferrajoli, A, Ravandi, F, Wierda, W G, O'Brien, S, Keating, M J, Burger, J A

“…Syk is a protein tyrosine kinase that couples B-cell receptor (BCR) activation with downstream signaling pathways, affecting cell survival and proliferation…”
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Global phylogeography with mixed-marker analysis reveals male-mediated dispersal in the endangered scalloped hammerhead shark (Sphyrna lewini) by Daly-Engel, Toby S, Seraphin, Kanesa D, Holland, Kim N, Coffey, John P, Nance, Holly A, Toonen, Robert J, Bowen, Brian W

“…The scalloped hammerhead shark, Sphyrna lewini, is a large endangered predator with a circumglobal distribution, observed in the open ocean but linked…”
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The Dual Syk/JAK Inhibitor Cerdulatinib Antagonizes B-cell Receptor and Microenvironmental Signaling in Chronic Lymphocytic Leukemia by Blunt, Matthew D, Koehrer, Stefan, Dobson, Rachel C, Larrayoz, Marta, Wilmore, Sarah, Hayman, Alice, Parnell, Jack, Smith, Lindsay D, Davies, Andrew, Johnson, Peter W M, Conley, Pamela B, Pandey, Anjali, Strefford, Jonathan C, Stevenson, Freda K, Packham, Graham, Forconi, Francesco, Coffey, Greg P, Burger, Jan A, Steele, Andrew J

“…B-cell receptor (BCR)-associated kinase inhibitors, such as ibrutinib, have revolutionized the treatment of chronic lymphocytic leukemia (CLL). However, these…”
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Changes in feeding behavior as possible indicators for the automatic monitoring of health disorders in dairy cows by González, L A, Tolkamp, B J, Coffey, M P, Ferret, A, Kyriazakis, I

“…Changes in short-term feeding behavior of dairy cows that occur with the onset of the health disorders ketosis, acute locomotory problems, and chronic lameness…”
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Identification of immune traits correlated with dairy cow health, reproduction and productivity by Banos, Georgios, Wall, Eileen, Coffey, Michael P, Bagnall, Ainsley, Gillespie, Sandra, Russell, George C, McNeilly, Tom N

“…Detailed biological analyses (e.g. epidemiological, genetic) of animal health and fitness in the field are limited by the lack of large-scale recording of…”
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α-Synuclein and anti-α-synuclein antibodies in Parkinson's disease, atypical Parkinson syndromes, REM sleep behavior disorder, and healthy controls by Smith, Lynnae M, Schiess, Mya C, Coffey, Mary P, Klaver, Andrea C, Loeffler, David A

“…α-synuclein is thought to play a key role in Parkinson's disease (PD) because it is the major protein in Lewy bodies, and because its gene mutations,…”
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Intake, Digestibility, Ruminal Fermentation, and In Situ Disappearance of Bermudagrass Hay by Lactating Beef Cows Offered Corn or Hominy Feed as Supplements at Two Different Rates by Nieman, Christine C, Madzonga, Zibani, Young-Kenworthy, Ashley N, Coffey, Kenneth P

“…Hominy feed (HF) has been evaluated in feedlot and dairy rations but has not been evaluated as a supplemental energy source for lactating beef cows. The…”
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Pre-BCR signaling in precursor B-cell acute lymphoblastic leukemia regulates PI3K/AKT, FOXO1 and MYC, and can be targeted by SYK inhibition by Köhrer, S, Havranek, O, Seyfried, F, Hurtz, C, Coffey, G P, Kim, E, ten Hacken, E, Jäger, U, Vanura, K, O'Brien, S, Thomas, D A, Kantarjian, H, Ghosh, D, Wang, Z, Zhang, M, Ma, W, Jumaa, H, Debatin, K-M, Müschen, M, Meyer, L H, Davis, R E, Burger, J A

“…Precursor-B-cell receptor (pre-BCR) signaling and spleen tyrosine kinase (SYK) recently were introduced as therapeutic targets for patients with B-cell acute…”
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A role for the outer retina in development of the intrinsic pupillary light reflex in mice by Vugler, A, Semo, M, Ortín-Martínez, A, Rojanasakul, A, Nommiste, B, Valiente-Soriano, F.J, García-Ayuso, D, Coffey, P, Vidal-Sanz, M, Gias, C

“…Highlights • We validate a new technique for studying the iPLR in mice. • The iPLR in mice can be elicited by very brief flashes of light. • This is the first…”
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The Genetic Architecture of Bovine Telomere Length in Early Life and Association With Animal Fitness by Ilska-Warner, Joanna J., Psifidi, Androniki, Seeker, Luise A., Wilbourn, Rachael V., Underwood, Sarah L., Fairlie, Jennifer, Whitelaw, Bruce, Nussey, Daniel H., Coffey, Mike P., Banos, Georgios

“…Health and survival are key goals for selective breeding in farm animals. Progress, however, is often limited by the low heritability of these animal fitness…”
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An Investigation of the Relationship Between the Second-to-Fourth Digit Ratio and Sagittal Synostosis by O’Sullivan, F., Bollard, S.M., O’Sullivan, G.P., Coffey, P., Bracken, S., Murray, D.J.

“…The most common presentation of nonsyndromic craniosynostosis is that of the sagittal suture. Amongst this subgroup there is a significant male preponderance…”
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Impact of single nucleotide polymorphisms in leptin, leptin receptor, growth hormone receptor, and diacylglycerol acyltransferase (DGAT1) gene loci on milk production, feed, and body energy traits of UK dairy cows by Banos, G, Woolliams, J A, Woodward, B W, Forbes, A B, Coffey, M P

“…The impact of 9 single nucleotide polymorphisms (SNP) in the leptin (LEP), leptin receptor (LEPR), growth hormone receptor (GHR), and diacylglycerol…”
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The use of mid-infrared spectrometry to predict body energy status of Holstein cows by McParland, S, Banos, G, Wall, E, Coffey, M P, Soyeurt, H, Veerkamp, R F, Berry, D P

“…Energy balance, especially in early lactation, is known to be associated with subsequent health and fertility in dairy cows. However, its inclusion in routine…”
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The heat-shock response co-inducer arimoclomol protects against retinal degeneration in rhodopsin retinitis pigmentosa by Parfitt, D A, Aguila, M, McCulley, C H, Bevilacqua, D, Mendes, H F, Athanasiou, D, Novoselov, S S, Kanuga, N, Munro, P M, Coffey, P J, Kalmar, B, Greensmith, L, Cheetham, M E

“…Retinitis pigmentosa (RP) is a group of inherited diseases that cause blindness due to the progressive death of rod and cone photoreceptors in the retina…”
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Challenges and Opportunities in Applying Genomic Selection to Ruminants Owned by Smallholder Farmers by Burrow, Heather M., Mrode, Raphael, Mwai, Ally Okeyo, Coffey, Mike P., Hayes, Ben J.

“…Genomic selection has transformed animal and plant breeding in advanced economies globally, resulting in economic, social and environmental benefits worth…”
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Technical note: Prediction of liveweight from linear conformation traits in dairy cattle by Banos, G, Coffey, M P

“…The objectives of this study were to derive phenotypic and genetic prediction equations of liveweight from linear conformation traits, and estimate genetic and…”
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Cerebrospinal Fluid Concentration of Key Autophagy Protein Lamp2 Changes Little During Normal Aging by Loeffler, David A, Klaver, Andrea C, Coffey, Mary P, Aasly, Jan O

“…Autophagy removes both functional and damaged intracellular macromolecules from cells via lysosomal degradation. Three autophagic mechanisms, namely…”
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Randomized, prospective, clinical evaluation of prosthodontic modalities for mandibular implant overdenture treatment by Burns, David R., DMD, Unger, John W., DDS, Coffey, James P., DDS, MS, Waldrop, Thomas C., DDS, MS, Elswick, Ronald K., PhD

“…Statement of problem Mandibular implant overdentures provide improved treatment outcome than conventional denture therapy, but there is controversy as to which…”
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Effect of Quebracho Tannin (Schinopsis quebracho-colorado (Schltdl.) F.A. Barkley and T. Meyer) on Silage Nutritive Value, Ergovaline Concentration, and Fermentation Parameters of Tall Fescue (Schedonorus arundinaceus (Shreb.) Dumort) with Two Dry-Matter Levels by Grote, Ally J., Nieman, Christine C., Thomas Jr, Ivan R., Coffey, Kenneth P., Muir, James P., Klotz, James L.

“…Tall fescue (Schedonorus arundinaceus (Shreb.) Dumort) is a cool-season forage grown in the mid-south United States of America that has the potential for…”
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