Search Results - "Coffen, David L."

Synthesis of the dideoxynucleosides "ddC" and "CNT" from glutamic acid, ribonolactone, and pyrimidine bases by Okabe, Masami, Sun, Ruen Chu, Tam, Steve Y. K, Todaro, Louis J, Coffen, David L

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Enantioselective synthesis of calcium channel blockers of the diltiazem group by Schwartz, Alan, Madan, Pradeep B, Mohacsi, Erno, O'Brien, Jay P, Todaro, Louis J, Coffen, David L

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Kinetic resolution of 2-substituted esters catalyzed by a lipase ex. Pseudomonas fluorescens by Kalaritis, Panos, Regenye, Ronald W, Partridge, John J, Coffen, David L

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Automated parallel synthesis of chalcone-based screening libraries by Powers, David G., Casebier, David S., Fokas, Demosthenes, Ryan, William J., Troth, Jonah R., Coffen, David L.

“…Using a variety of condensation and cyclization reactions, nine combinatorial arrays of individual chalcone derivatives, over 74,000 in all, were produced in…”
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Solution phase synthesis of a spiro[pyrrolidine-2,3′-oxindole] library via a three component 1,3-dipolar cycloaddition reaction by Fokas, Demosthenes, Ryan, William J., Casebier, David S., Coffen, David L.

“…A combinatorial library of 26,500 spiro[pyrrolidine-2,3′-oxindoles] was prepared in a single-compound format by a facile intermolecular 1,3-dipolar…”
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Potent and selective inhibitors of bacterial methionyl tRNA synthetase derived from an oxazolone–dipeptide scaffold by Tandon, Manish, Coffen, David L, Gallant, Paul, Keith, Dennis, Ashwell, Mark A

“…The preparation and structure–activity relationships (SARs) of potent and selective small molecule inhibitors of bacterial methionyl-tRNA synthetase (MetRS)…”
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Enzymic enhancement of n-3 fatty acid content in fish oils by Maehr, H, Zenchoff, G, Coffen, D.L

“…Commercially available fish oils with n−3 fatty acid contents ranging from 29 to 34% were converted enzymically, with Amano P lipase, to mixtures of glycerides…”
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Synthesis of a biologically active vitamin D2 metabolite by Choudhry, Satish C, Belica, Peter S, Coffen, David L, Focella, Antonino, Maehr, Hubert, Manchand, Percy S, Serico, Lucia, Yang, Roxana T

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Structure, absolute configuration, and total synthesis of an acid-catalyzed rearrangement product of bicyclomycin by Maag, Hans, Blount, John F, Coffen, David L, Steppe, Thomas V, Wong, Frederick

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Syntheses of an antipsychotic pyrrolo[2,3-g]isoquinoline from areca alkaloids by Coffen, David L, Hengartner, Urs, Katonak, David A, Mulligan, Mary E, Burdick, David C, Olson, Gary L, Todaro, Louis J

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A short synthesis of aromatic analogs of the aranotins by Coffen, David L, Katonak, David A, Nelson, Nels R, Sancilio, Fred D

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Synthetic quinine analogs. III. Frangomeric and anchimeric processes in the preparation and reactions of .alpha.,.beta.-epoxy ketones by Coffen, David L, Korzan, D. G

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Palladium-catalyzed carbonyl insertion route to pyrido[2-1-b]quinazoline derivatives by Tilley, Jefferson W, Coffen, David L, Schaer, Beatrice H, Lind, Joan

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2-Benzazepines. 8. Zerovalent nickel mediated biaryl synthesis of an anxiolytic pyrimido[5,4-d][2]benzazepine by Coffen, David L, Schaer, Beatrice, Bizzarro, Fred T, Cheung, Julia B

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Friedlaendar synthesis and rearrangement of 10-(o-fluoropheny)-1,4-ethanobezo[b]-1,5-naphthyridines to benzo[b]indolo[3,2,1-d,e]-1,5-naphthyridines by Coffen, David L, Wong, Frederick

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Tetrathioethylenes by Coffen, David L, Chambers, James Q, Williams, Denis R, Garrett, P. E, Canfield, N. D

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Quinazolines and 1,4-benzodiazepines. LXX. v-Triazolo[1,5-a][1,4]benzodiazepines by Coffen, David L, Fryer, R. Ian, Katonak, David A, Wong, Frederick

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Synthesis of some 2-aminofurans from cyanoacetone enolate and their rearrangement to 3-cyanopyrroles with ammonia by Blount, John F, Coffen, David L, Katonak, David A

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Incorporation of carbohydrates and peptides into large triazine-based screening libraries using automated parallel synthesis by Gustafson, Gary R., Baldino, Carmen M., O'Donnell, Mary-Margaret E., Sheldon, Adrian, Tarsa, Robert J., Verni, Christopher J., Coffen, David L.

“…A procedure for the sequential, selective derivatization of cyanuric chloride that allows for the incorporation of carbohydrates and peptides has been…”
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Isomeric transition metal complexes of trans-2-[(2-quinolyl)methylene]-3-quinuclidinones by Coffen, David L, McEntee, T. E

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