Search Results - "Cofer, Gary P"

A high-resolution interactive atlas of the human brainstem using magnetic resonance imaging by Adil, Syed M., Calabrese, Evan, Charalambous, Lefko T., Cook, James J., Rahimpour, Shervin, Atik, Ahmet F., Cofer, Gary P., Parente, Beth A., Johnson, G. Allan, Lad, Shivanand P., White, Leonard E.

“…•One complete, postmortem human brainstem was scanned with MRI for 208 h.•Anatomic and diffusion images achieved isotropic resolutions of 50 and 200 μm.•Ninety…”
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Hyperpolarized Xe MR imaging of alveolar gas uptake in humans by Cleveland, Zackary I, Cofer, Gary P, Metz, Gregory, Beaver, Denise, Nouls, John, Kaushik, S Sivaram, Kraft, Monica, Wolber, Jan, Kelly, Kevin T, McAdams, H Page, Driehuys, Bastiaan

“…One of the central physiological functions of the lungs is to transfer inhaled gases from the alveoli to pulmonary capillary blood. However, current measures…”
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Volumetric analysis of the aging auditory pathway using high resolution magnetic resonance histology by Du, Eric Y., Ortega, Briana K., Ninoyu, Yuzuru, Williams, Robert W., Cofer, Gary P., Cook, James J., Hornburg, Kathryn J., Qi, Yi, Johnson, G. Allan, Friedman, Rick A.

“…Numerous shown consequences of age-related hearing loss have been unveiled; however, the relationship of the cortical and subcortical structures of the…”
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Transcriptome analysis identifies an ASD-Like phenotype in oligodendrocytes and microglia from C58/J amygdala that is dependent on sex and sociability by Dalton, George D, Siecinski, Stephen K, Nikolova, Viktoriya D, Cofer, Gary P, Hornburg, Kathryn J, Qi, Yi, Johnson, G Allan, Jiang, Yong-Hui, Moy, Sheryl S, Gregory, Simon G

“…Autism Spectrum Disorder (ASD) is a group of neurodevelopmental disorders with higher incidence in males and is characterized by atypical verbal/nonverbal…”
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Characterization of subtle brain abnormalities in a mouse model of Hedgehog pathway antagonist-induced cleft lip and palate by Lipinski, Robert J, Holloway, Hunter T, O'Leary-Moore, Shonagh K, Ament, Jacob J, Pecevich, Stephen J, Cofer, Gary P, Budin, Francois, Everson, Joshua L, Johnson, G Allan, Sulik, Kathleen K

“…Subtle behavioral and cognitive deficits have been documented in patient cohorts with orofacial clefts (OFCs). Recent neuroimaging studies argue that these…”
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Optimizing Diffusion Imaging Protocols for Structural Connectomics in Mouse Models of Neurological Conditions by Anderson, Robert J, Long, Christopher M, Calabrese, Evan D, Robertson, Scott H, Johnson, G Allan, Cofer, Gary P, O'Brien, Richard J, Badea, Alexandra

“…Network approaches provide sensitive biomarkers for neurological conditions, such as Alzheimer's disease (AD). Mouse models can help advance our understanding…”
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Magnetic resonance histology for morphologic phenotyping by Johnson, G. Allan, Cofer, Gary P., Fubara, Boma, Gewalt, Sally L., Hedlund, Laurence W., Maronpot, Robert R.

“…Magnetic resonance histology (MRH) images of the whole mouse have been acquired at 100‐micron isotropic resolution at 2.0T with image arrays of 256 × 256 ×…”
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Merged magnetic resonance and light sheet microscopy of the whole mouse brain by Johnson, G Allan, Tian, Yuqi, Ashbrook, David G, Cofer, Gary P, Cook, James J, Gee, James C, Hall, Adam, Hornburg, Kathryn, Kaczorowski, Catherine C, Qi, Yi, Yeh, Fang-Cheng, Wang, Nian, White, Leonard E, Williams, Robert W

“…We have developed workflows to align 3D magnetic resonance histology (MRH) of the mouse brain with light sheet microscopy (LSM) and 3D delineations of the same…”
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Susceptibility tensor imaging and tractography of collagen fibrils in the articular cartilage by Wei, Hongjiang, Gibbs, Eric, Zhao, Peida, Wang, Nian, Cofer, Gary P., Zhang, Yuyao, Johnson, G. Allan, Liu, Chunlei

“…Purpose To investigate the B0 orientation‐dependent magnetic susceptibility of collagen fibrils within the articular cartilage and to determine whether…”
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Diffusion-weighted hyperpolarized 129Xe MRI in healthy volunteers and subjects with chronic obstructive pulmonary disease by Kaushik, S. Sivaram, Cleveland, Zackary I., Cofer, Gary P., Metz, Gregory, Beaver, Denise, Nouls, John, Kraft, Monica, Auffermann, William, Wolber, Jan, McAdams, H. Page, Driehuys, Bastiaan

“…Given its greater availability and lower cost, 129Xe apparent diffusion coefficient (ADC) MRI offers an alternative to 3He ADC MRI. To demonstrate the…”
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Susceptibility tensor imaging of the kidney and its microstructural underpinnings by Xie, Luke, Dibb, Russell, Cofer, Gary P., Li, Wei, Nicholls, Peter J., Johnson, G. Allan, Liu, Chunlei

“…Purpose The purpose of this study was to determine whether susceptibility tensor imaging (STI) could overcome limitations of current techniques to detect…”
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In vivo MRI using real-time production of hyperpolarized 129Xe by Driehuys, Bastiaan, Pollaro, Jim, Cofer, Gary P.

“…MR imaging of hyperpolarized (HP) nuclei is challenging because they are typically delivered in a single dose of nonrenewable magnetization, from which the…”
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Whole mouse brain connectomics by Allan Johnson, G., Wang, Nian, Anderson, Robert J., Chen, Min, Cofer, Gary P., Gee, James C., Pratson, Forrest, Tustison, Nicholas, White, Leonard E.

“…Methods have been developed to allow quantitative connectivity of the whole fixed mouse brain by means of magnetic resonance imaging (MRI). We have translated…”
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Hyperpolarized 129Xe MR Imaging of Alveolar Gas Uptake in Humans by Cleveland, Zackary I., Cofer, Gary P., Metz, Gregory, Beaver, Denise, Nouls, John, Kaushik, S. Sivaram, Kraft, Monica, Wolber, Jan, Kelly, Kevin T., McAdams, H. Page, Driehuys, Bastiaan

“…Background One of the central physiological functions of the lungs is to transfer inhaled gases from the alveoli to pulmonary capillary blood. However, current…”
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The fornix provides multiple biomarkers to characterize circuit disruption in a mouse model of Alzheimer's disease by Badea, Alexandra, Kane, Lauren, Anderson, Robert J., Qi, Yi, Foster, Mark, Cofer, Gary P., Medvitz, Neil, Buckley, Anne F., Badea, Andreas K., Wetsel, William C., Colton, Carol A.

“…Multivariate biomarkers are needed for detecting Alzheimer's disease (AD), understanding its etiology, and quantifying the effect of therapies. Mouse models…”
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Quantitative analysis of hyperpolarized 129Xe ventilation imaging in healthy volunteers and subjects with chronic obstructive pulmonary disease by Virgincar, Rohan S., Cleveland, Zackary I., Sivaram Kaushik, S., Freeman, Matthew S., Nouls, John, Cofer, Gary P., Martinez-Jimenez, Santiago, He, Mu, Kraft, Monica, Wolber, Jan, Page McAdams, H., Driehuys, Bastiaan

“…In this study, hyperpolarized 129Xe MR ventilation and 1H anatomical images were obtained from three subject groups: young healthy volunteers (HVs), subjects…”
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3He MRI in mouse models of asthma by Driehuys, Bastiaan, Walker, Julia, Pollaro, Jim, Cofer, Gary P., Mistry, Nilesh, Schwartz, David, Johnson, G. Allan

“…In the study of asthma, a vital role is played by mouse models, because knockout or transgenic methods can be used to alter disease pathways and identify…”
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Imaging alveolar–capillary gas transfer using hyperpolarized 129Xe MRI by Driehuys, Bastiaan, Cofer, Gary P, Pollaro, Jim, Mackel, Julie Boslego, Hedlund, Laurence W, Johnson, G Allan

“…Effective pulmonary gas exchange relies on the free diffusion of gases across the thin tissue barrier separating airspace from the capillary red blood cells…”
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Improved preparation of chick embryonic samples for magnetic resonance microscopy by Zhang, Xiaowei, Yelbuz, T. Mesud, Cofer, Gary P., Choma, Michael A., Kirby, Margaret L., Johnson, G. Allan

“…Previous work demonstrated the power of three‐dimensional (3D) magnetic resonance microscopy (MRM) to follow complicated morphologic development in the…”
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Diffusion tensor imaging using multiple coils for mouse brain connectomics by Nouls, John C., Badea, Alexandra, Anderson, Robert B.J., Cofer, Gary P., Allan Johnson, G.

“…The correlation between brain connectivity and psychiatric or neurological diseases has intensified efforts to develop brain connectivity mapping techniques on…”
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