Search Results - "Coester, Conrad"

Optimized dispersion of nanoparticles for biological in vitro and in vivo studies by Bihari, Peter, Vippola, Minnamari, Schultes, Stephan, Praetner, Marc, Khandoga, Alexander G, Reichel, Christoph A, Coester, Conrad, Tuomi, Timo, Rehberg, Markus, Krombach, Fritz

“…The aim of this study was to establish and validate a practical method to disperse nanoparticles in physiological solutions for biological in vitro and in vivo…”
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New doxorubicin-loaded phospholipid microbubbles for targeted tumor therapy: Part I — Formulation development and in-vitro characterization by Tinkov, Steliyan, Winter, Gerhard, Coester, Conrad, Bekeredjian, Raffi

“…Despite high antitumor efficacy and a broad application spectrum, clinical treatment with anthracycline chemotherapeutics is often limited by severe adverse…”
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New doxorubicin-loaded phospholipid microbubbles for targeted tumor therapy: In-vivo characterization by Tinkov, Steliyan, Coester, Conrad, Serba, Susanne, Geis, Nicolas A., Katus, Hugo A., Winter, Gerhard, Bekeredjian, Raffi

“…Doxorubicin (DOX) is a potent chemotherapy drug that is often limited by severe adverse effects such as cardiac toxicity and myelosupression. Drug targeting…”
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Delivery by Cationic Gelatin Nanoparticles Strongly Increases the Immunostimulatory Effects of CpG Oligonucleotides by Zwiorek, Klaus, Bourquin, Carole, Battiany, Julia, Winter, Gerhard, Endres, Stefan, Hartmann, Gunther, Coester, Conrad

“…Purpose Cationized gelatin nanoparticles (GNPs) were used as carrier to improve delivery of immunostimulatory CpG oligonucleotides (CpG ODN) both in vitro and…”
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Targeting CpG Oligonucleotides to the Lymph Node by Nanoparticles Elicits Efficient Antitumoral Immunity by Bourquin, Carole, Anz, David, Zwiorek, Klaus, Lanz, Anna-Lisa, Fuchs, Sebastian, Weigel, Sarah, Wurzenberger, Cornelia, von der Borch, Philip, Golic, Michaela, Moder, Stefan, Winter, Gerhard, Coester, Conrad, Endres, Stefan

“…Viral nucleic acids are recognized by specific pattern-recognition receptors of the Toll-like and RIG-I-like receptor families. Synthetic DNA and RNA…”
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A Nebulized Gelatin Nanoparticle-Based CpG Formulation is Effective in Immunotherapy of Allergic Horses by Klier, John, Fuchs, Sebastian, May, Anna, Schillinger, Ulrike, Plank, Christian, Winter, Gerhard, Gehlen, Heidrun, Coester, Conrad

“…ABSTRACT Purpose In the recent years, nanotechnology has boosted the development of potential drug delivery systems and material engineering on nanoscale basis…”
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Ultrasound Targeted Microbubble Destruction Increases Capillary Permeability in Hepatomas by Bekeredjian, Raffi, Kroll, Richard D, Fein, Evelyn, Tinkov, Steliyan, Coester, Conrad, Winter, Gerhard, Katus, Hugo A, Kulaksiz, Hasan

“…Abstract Ultrasound-targeted microbubble destruction (UTMD) has evolved as a promising tool for organ-specific gene and drug delivery. Taking advantage of high…”
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Matrix-loaded biodegradable gelatin nanoparticles as new approach to improve drug loading and delivery by Ofokansi, Kenneth, Winter, Gerhard, Fricker, Gert, Coester, Conrad

“…SEM photomicrographs of FITC-D-loaded (A) and FITC-D-unloaded (B) gelatin nanoparticles showing very smooth and spherical particles. Note that the particles…”
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Microbubbles as ultrasound triggered drug carriers by Tinkov, Steliyan, Bekeredjian, Raffi, Winter, Gerhard, Coester, Conrad

“…Originally developed as contrast agents for ultrasound imaging and diagnostics, in the past years, microbubbles have made their way back from the patients'…”
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In vitro uptake of gelatin nanoparticles by murine dendritic cells and their intracellular localisation by Coester, Conrad, Nayyar, Paras, Samuel, John

“…The long term goal of this study is to develop an efficient nanoscopic vaccine delivery system, based on the biodegradable and natural polymer gelatin, to…”
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Asymmetrical Flow Field-Flow Fractionation and Multiangle Light Scattering for Analysis of Gelatin Nanoparticle Drug Carrier Systems by Fraunhofer, Wolfgang, Winter, Gerhard, Coester, Conrad

“…The physicochemical properties of nanosized colloidal drug carrier systems are of great influence on drug efficacy. Consequently, a broad spectrum of…”
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Towards an inhalative in vivo application of immunomodulating gelatin nanoparticles in horse-related preformulation studies by Fuchs, Sebastian, Klier, John, May, Anna, Winter, Gerhard, Coester, Conrad, Gehlen, Heidrun

“…Delivering active ingredients using biocompatible and biodegradable carriers such as gelatin nanoparticles (GNPs) to the lung constitutes a promising…”
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Ultrasonic resonator technology as a new quality control method evaluating gelatin nanoparticles by Fuchs, Sebastian, Winter, Gerhard, Coester, Conrad

“…Nanomedicine is a quickly evolving field where more and more possible applications become evident and start entering clinical trials or even the market…”
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Immunostimulation of bronchoalveolar lavage cells from recurrent airway obstruction-affected horses by different CpG-classes bound to gelatin nanoparticles by Klier, John, May, Anna, Fuchs, Sebastian, Schillinger, Ulrike, Plank, Christian, Winter, Gerhard, Gehlen, Heidrun, Coester, Conrad

“…Recurrent airway obstruction (RAO) in horses has become a common problem in stabled horses in industrialized countries and deserves new therapeutic strategies…”
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Erratum to: A Nebulized Gelatin Nanoparticle-Based CpG Formulation is Effective in Immunotherapy of Allergic Horses by Klier, John, Fuchs, Sebastian, May, Anna, Schillinger, Ulrike, Plank, Christian, Winter, Gerhard, Coester, Conrad, Gehlen, Heidrun

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Formulation development of freeze-dried oligonucleotide-loaded gelatin nanoparticles by Zillies, Jan C., Zwiorek, Klaus, Hoffmann, Florian, Vollmar, Angelika, Anchordoquy, Thomas J., Winter, Gerhard, Coester, Conrad

“…The freeze-drying properties of gelatin nanoparticles were investigated with the goal of providing practicable nanoparticle formulations for in vitro…”
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In vitro effects of CpG oligodeoxynucleotides delivered by gelatin nanoparticles on canine peripheral blood mononuclear cells of atopic and healthy dogs - a pilot study by Prélaud, Ana Rostaher, Fuchs, Sebastian, Weber, Karin, Winter, Gerhard, Coester, Conrad, Mueller, Ralf S.

“…Background Cytosine‐phosphate‐guanine (CpG) oligodeoxynucleotides offer a novel promising immunotherapeutic approach for atopic dermatitis (AD) both in humans…”
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Analysis of poly(D, L-lactic-co-glycolic acid) nanosphere uptake by human dendritic cells and macrophages in vitro by LUTSIAK, M. E, ROBINSON, Deborah R, COESTER, Conrad, KWON, Glen S, SAMUEL, John

“…The purpose of this study was to demonstrate and characterize phagocytosis of poly(D,L-lactic-co-glycolic acid) (PLGA) nanospheres by human dendritic cells…”
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Method for Quantifying the PEGylation of Gelatin Nanoparticle Drug Carrier Systems Using Asymmetrical Flow Field-Flow Fractionation and Refractive Index Detection by Zillies, Jan C, Zwiorek, Klaus, Winter, Gerhard, Coester, Conrad

“…The PEGylation of colloidal drug carrier systems protects them from a rapid clearance from the blood stream and therefore prolongs their plasma half-lives…”
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Matrix-Ioaded biodegradable gelatin nanoparticles as new approach to improve drug loading and delivery by OFOKANSI, Kenneth, WINTER, Gerhard, FRICKER, Gert, COESTER, Conrad

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