Search Results - "Coenegracht, P M"

Optimisation of high-performance liquid chromatography with diode array detection using an automatic peak tracking procedure based on augmented iterative target transformation factor analysis by van Zomeren, P V, Hoogvorst, A, Coenegracht, P M J, de Jong, G J

“…An automated method for the optimisation of high-performance liquid chromatography is developed. First of all, the sample of interest is analysed with various…”
Get more information

Comparison of migration modeling in micellar electrokinetic chromatography by linear regression and by use of an artificial neural network by Metting, H. J, van Zomeren, P. V, van der Ley, C. P, Coenegracht, P. M. J, de Jong, G. J

“…The concentrations of modifier (methanol or acetonitrile) and surfactant (sodium dodecyl sulfate, SDS) in the running buffer are important factors influencing…”
Get full text

Artificial neural network predictions of urinary calculus compositions analyzed with infrared spectroscopy by Volmer, M, Wolthers, B G, Metting, H J, de Haan, T H, Coenegracht, P M, van der Slik, W

“…Infrared (IR) spectroscopy is used to analyze urinary calculus (renal stone) constituents. However, interpretation of IR spectra for quantifying urinary…”
Get more information

Effect of an external resistance to airflow on the inspiratory flow curve by de Koning, J.P, van der Mark, Th.W, Coenegracht, P.M.J, Tromp, Th.F.J, Frijlink, H.W

“…Inhalation is a convenient way to deliver drugs to the respiratory tract in the treatment of respiratory diseases. For dry powder inhalers (DPI's), the…”
Get full text

Development of a laboratory robotic system for automated bioanalytical methods--I. The determination of theophylline in human plasma: a comparison between the robotized and manual method by Hempenius, J, Wieling, J, Jonkman, J H, de Noord, O E, Coenegracht, P M, Doornbos, D A

“…The quality of bioanalytical methods is often determined by the quality of sample preparation. Using a robot for sample treatment may give better results than…”
Get more information

A chemometric investigation of the selectivity of multisolvent mobile phase systems in RP-HPLC by COENEGRACHT, P. M. J, METTING, H. J, SMILDE, A. K, COENEGRACHT-LAMERS, P. J. M

Get full text

Resolution optimisation in micellar electrokinetic chromatography using empirical models by van Zomeren, P.V., Hilhorst, M.J., Coenegracht, P.M.J., de Jong, G.J.

“…Theoretical and empirical models can be used to model the migration or separation characteristics in micellar electrokinetic chromatography in order to…”
Get full text

Development of a laboratory robotic system for automated bioanalytical methods--II. A robot computer program for guarding totally automated bioanalytical methods by Wieling, J, Hempenius, J, Jeuring, H J, Jonkman, J H, Coenegracht, P M, Doornbos, D A

“…The application of fully automated, unattended sample preparation performed by a laboratory robot for the analysis of drugs in biological samples requires the…”
Get more information

Comparison of several curve resolution methods for drug impurity profiling using high-performance liquid chromatography with diode array detection by van Zomeren, P.V, Darwinkel, H, Coenegracht, P.M.J, de Jong, G.J

“…The performance of five curve resolution methods was compared systematically for the identification and quantification of impurities in drug impurity…”
Get full text

Simultaneous resolution of overlapping peaks in high-performance liquid chromatography and micellar electrokinetic chromatography with diode array detection using augmented iterative target transformation factor analysis: Chemical Separations and Chemometrics by VAN ZOMEREN, P. V, METTING, H. J, COENEGRACHT, P. M. J, DE JONG, G. J

Get full text

Precise, recording amperometric titrator. Automatic correction of the titration curve for dilution of the sample solution with the titrant by Coenegracht, P. M. J

Get full text

Simultaneous resolution of overlapping peaks in high-performance liquid chromatography and micellar electrokinetic chromatography with diode array detection using augmented iterative target transformation factor analysis by van Zomeren, P.V., Metting, H.J., Coenegracht, P.M.J., de Jong, G.J.

“…In this paper, augmentation has been applied to data matrices, which originate from hyphenated methods that share the same mode of detection, but use different…”
Get full text

Multivariate modelling of the pharmaceutical two-step process of wet granulation and tableting with multiblock partial least squares by Westerhuis, Johan A., Coenegracht, Pierre M. J.

“…The pharmaceutical process of wet granulation and tableting is described as a two‐step process. Besides the process variables of both steps and the composition…”
Get full text

A rapid and specific method for the determination of traces of thallium directly in urine by differential pulse anodic stripping voltammetry by Franke, J P, Coenegracht, P M, de Zeeuw, R A

“…The applicability of differential pulse anodic stripping voltammetry to the direct qualitative and quantitative analysis of thallium in urine has been…”
Get full text

Neural networks in high-performance liquid chromatography optimization: response surface modeling by Metting, Harm J., Coenegrach, Pierre M.J.

“…The usefulness of artificial neural networks for response surface modeling in HPLC optimization is compared with (non-)linear regression methods. The number of…”
Get full text

Comparison of prediction power between theoretical and neural-network models in ion-interaction chromatography by Sacchero, Giovanni, Concetta Bruzzoniti, Maria, Sarzanini, Corrado, Mentasti, Edoardo, Metting, Harm J, Coenegracht, Pierre M.J

“…The separation by ion-interaction chromatography (IIC) of metal complexes having single and double charges has been studied in order to compare the prediction…”
Get full text

Optimization of a novel two-phase potentiometric titration method of barbiturates with mercury (II). Part II: Experimental evaluation by Coenegracht, P M, Metting, H J, Doornbos, D A

“…A two-phase potentiometric titration procedure of barbiturates with mercury(II) was developed. The composition of the formed mercury-barbiturate complexes was…”
Get more information

Optimization of a novel two-phase potentiometric titration method of barbiturates with mercury (II). Part I: Theory by Coenegracht, P M, Metting, H J, Doornbos, D A

“…A two-phase potentiometric titration procedure for barbiturates with mercury(II) was developed. In the new titration procedure the barbituric acid derivative…”
Get more information

Multivariate modelling of the tablet manufacturing process with wet granulation for tablet optimization and in-process control by Westerhuis, Johan A, Coenegracht, Pierre M.J, Lerk, Coenraad F

“…The process of tablet manufacturing with granulation is described as a two-step process. The first step comprises wet granulation of the powder mixture, and in…”
Get full text

The automatic amperometric and potentiometric microtitration of pharmaceutically important sulfanilamide derivatives by diazotization with nitrite by Coenegracht, P M, Franke, J P, Metting, H J

Get more information