Search Results - "Coelho, Paulo Marcos Z."
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Selecting targets for the diagnosis of Schistosoma mansoni infection: An integrative approach using multi-omic and immunoinformatics data
Published in PloS one (17-08-2017)“…In order to effectively control and monitor schistosomiasis, new diagnostic methods are essential. Taking advantage of computational approaches provided by…”
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Schistosoma mansoni: a method for inducing resistance to praziquantel using infected Biomphalaria glabrata snails
Published in Memórias do Instituto Oswaldo Cruz (01-03-2011)“…To elucidate the mechanisms of antischistosoma resistance, drug-resistant Schistosoma mansoni laboratory isolates are essential. We developed a new method for…”
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Schistosoma mansoni granulomas in the skeletal striated muscles in the murine model of neuroschistosomiasis: histological findings
Published in Memórias do Instituto Oswaldo Cruz (01-01-2020)“…Schistosomiasis mansoni presents many clinical manifestations during migration of schistosomes in their hosts, including diarrhea, hepatomegaly, splenomegaly,…”
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Characterisation of ocular involvement in an experimental model of neuroschistosomiasis mansoni
Published in Memórias do Instituto Oswaldo Cruz (01-01-2019)“…The Global Burden of Disease Study 2010 listed schistosomiasis among the leading 100 causes of death in Brazil, responsible for 3.6% of the estimated total of…”
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embryonic development of Schistosoma mansoni eggs: proposal for a new staging system
Published in Development genes and evolution (01-05-2009)“…Schistosomiasis is a water-borne parasitic illness caused by neoophoran trematodes of the genus Schistosoma. Using classical histological techniques and…”
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Use of a saline gradient for the diagnosis of schistosomiasis
Published in Memórias do Instituto Oswaldo Cruz (01-08-2009)“…The development of novel methods for parasitological diagnosis that are both highly sensitive and low in cost has been strongly recommended by the World Health…”
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Further evaluation of an updated PCR assay for the detection of Schistosoma mansoni DNA in human stool samples
Published in Memórias do Instituto Oswaldo Cruz (01-12-2009)“…A previously reported sensitive PCR assay for the detection of Schistosoma mansoni DNA was updated and evaluated. Changes in the DNA extraction method,…”
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A new miracidia hatching device for diagnosing schistosomiasis
Published in Memórias do Instituto Oswaldo Cruz (01-02-2008)“…It is still imperative to develop a parasitological technique highly sensitive for diagnosing schistosomiasis in epidemiological and individual surveys. A…”
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Phylogenetic analysis of Biomphalaria tenagophila (Orbigny, 1835) (Mollusca: Gastropoda)
Published in Memórias do Instituto Oswaldo Cruz (01-07-2010)“…Mitochondrial DNA of Biomphalaria tenagophila , a mollusc intermediate host of Schistosoma mansoni in Brazil, was sequenced and characterised. The genome size…”
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Antibody reactivity against potato apyrase, a protein that shares epitopes with Schistosoma mansoni ATP diphosphohydrolase isoforms, in acute and chronically infected mice, after chemotherapy and reinfection
Published in Memórias do Instituto Oswaldo Cruz (01-07-2010)“…Schistosoma mansoni ATP diphosphohydrolase isoforms and potato apyrase share conserved epitopes. By enzyme-linked immunosorbent assays, elevated levels of IgM,…”
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Suitability of commercially available POC-CCA tests for schistosomiasis: Considerations for efficiency, reproducibility and decision making criteria for field application in areas of low endemicity
Published in Journal of immunological methods (01-09-2019)“…Point of care tests would be valuable for field diagnosis. However, high sensitivity will likely be required in low endemicity sets where individuals with low…”
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Innovative methodology for point-of-care circulating cathodic antigen with rapid urine concentration for use in the field for detecting low Schistosoma mansoni infection and for control of cure with high accuracy
Published in Transactions of the Royal Society of Tropical Medicine and Hygiene (01-01-2018)“…Abstract Background Prior to eliminating schistosomiasis, efforts must address accurate and fast individual diagnosis. Diagnosis is still inaccurate by…”
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A new method for fixing Biomphalaria glabrata for histologic studies, using shell perforation
Published in Memórias do Instituto Oswaldo Cruz (01-03-2002)“…A new technique for fixation of Biomphalaria glabrata for histologic studies is described. It consists in performing several external holes in the shell,…”
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Proteome analysis of the cardiac and pericardial tissue of Biomphalaria tenagophila populations susceptible and resistant to Schistosoma mansoni infection
Published in Acta tropica (01-03-2008)“…For a better comprehension of the parasite–host interaction, proteins expressed by the cardiac and pericardial tissues were compared between susceptible (Cabo…”
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Schistosoma mansoni: reinfections and concomitant immunity in mice. Importance of perfusion time after challenge infection for evaluation of immunoprotection
Published in Memórias do Instituto Oswaldo Cruz (01-08-1995)“…The concomitant immunity in the presence of repeated infections (with 15 cercariae) was studied in mice sacrificed on the 20th day after each infection. The…”
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Schistosoma mansoni in mice: modulation of granulomatous response after reinfection and chemotherapeutic treatment
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-09-1994)“…Mice previously infected with Schistosoma mansoni, and cured by specific treatment (400mg/kg oxamniquine, p.o.) in the chronic phase of the disease, were…”
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Aspects of the granulomatous reaction in the liver of mice infected and reinfected with two different geographical strains of Schistosoma mansoni
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-12-1994)“…In this study, which was undertaken in relation to the histopathologic behavior of two different strains (LE-Belo Horizonte, MG and SJ-São José dos Campos, SP)…”
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Overcoming challenges in the diagnosis of Schistosoma mansoni infections using recombinant protein technology
Published in The FASEB journal (01-04-2016)“…Abstract only Control constraints of Schistosomiasis include the lack of diagnostic methods with high sensitivity. We develop a prospective study in southeast…”
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