Search Results - "Coelho, Miguel B"
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Functional interactions between polypyrimidine tract binding protein and PRI peptide ligand containing proteins
Published in Biochemical Society transactions (15-08-2016)“…Polypyrimidine tract binding protein (PTBP1) is a heterogeneous nuclear ribonucleoprotein (hnRNP) that plays roles in most stages of the life-cycle of pre-mRNA…”
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MBNL1 and PTB cooperate to repress splicing of Tpm1 exon 3
Published in Nucleic acids research (01-05-2013)“…Exon 3 of the rat α-tropomyosin (Tpm1) gene is repressed in smooth muscle cells, allowing inclusion of the mutually exclusive partner exon 2. Two key types of…”
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Crystallographic Analysis of Polypyrimidine Tract-Binding Protein-Raver1 Interactions Involved in Regulation of Alternative Splicing
Published in Structure (London) (07-12-2011)“…The polypyrimidine tract-binding protein (PTB) is an important regulator of alternative splicing. PTB-regulated splicing of α-tropomyosin is enhanced by…”
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In Vivo Requirement of the Small Subunit of U2AF for Recognition of a Weak 3′ Splice Site
Published in Molecular and Cellular Biology (01-11-2006)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Nuclear matrix protein Matrin3 regulates alternative splicing and forms overlapping regulatory networks with PTB
Published in The EMBO journal (04-03-2015)“…Matrin3 is an RNA‐ and DNA‐binding nuclear matrix protein found to be associated with neural and muscular degenerative diseases. A number of possible functions…”
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Matrin3: connecting gene expression with the nuclear matrix
Published in Wiley interdisciplinary reviews. RNA (01-05-2016)“…As indicated by its name, Matrin3 was discovered as a component of the nuclear matrix, an insoluble fibrogranular network that structurally organizes the…”
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Stoichiometry of a regulatory splicing complex revealed by single-molecule analyses
Published in The EMBO journal (07-07-2010)“…Splicing is regulated by complex interactions of numerous RNA‐binding proteins. The molecular mechanisms involved remain elusive, in large part because of…”
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Regulation of alternative pre-mRNA splicing
Published in Methods in molecular biology (Clifton, N.J.) (2014)“…Alternative splicing plays a prevalent role in generating functionally diversified proteomes from genomes with a more limited repertoire of protein-coding…”
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