Search Results - "Coelho, Ana L."

Quercetin Enhances Ligand-induced Apoptosis in Senescent Idiopathic Pulmonary Fibrosis Fibroblasts and Reduces Lung Fibrosis In Vivo by Hohmann, Miriam S, Habiel, David M, Coelho, Ana L, Verri, Jr, Waldiceu A, Hogaboam, Cory M

“…Although cellular senescence may be a protective mechanism in modulating proliferative capacity, fibroblast senescence is now recognized as a key pathogenic…”
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Targeting of TAM Receptors Ameliorates Fibrotic Mechanisms in Idiopathic Pulmonary Fibrosis by Espindola, Milena S, Habiel, David M, Narayanan, Rohan, Jones, Isabelle, Coelho, Ana L, Murray, Lynne A, Jiang, Dianhua, Noble, Paul W, Hogaboam, Cory M

“…Idiopathic pulmonary fibrosis (IPF) is characterized by aberrant lung remodeling, which progressively abolishes lung function in an RTK (receptor tyrosine…”
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Epigenetic regulation of the alternatively activated macrophage phenotype by Ishii, Makoto, Wen, Haitao, Corsa, Callie A.S., Liu, Tianju, Coelho, Ana L., Allen, Ronald M., Carson, William F., Cavassani, Karen A., Li, Xiangzhi, Lukacs, Nicholas W., Hogaboam, Cory M., Dou, Yali, Kunkel, Steven L.

“…Alternatively activated (M2) macrophages play critical roles in diverse chronic diseases, including parasite infections, cancer, and allergic responses…”
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Axl receptor blockade ameliorates pulmonary pathology resulting from primary viral infection and viral exacerbation of asthma by Shibata, Takehiko, Habiel, David M, Coelho, Ana L, Kunkel, Steven L, Lukacs, Nicholas W, Hogaboam, Cory M

“…Viruses use Tyro3, Axl, and Mertk (TAM) receptor tyrosine kinases to infect and modulate the immune properties of various cell types, which led us to…”
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Effects of Mannosylerythritol-Lipids-B on Cutibacterium acnes ATCC 6919 by Coelho, Ana L. S., Laroque, Denise A., Feuser, Paulo E., de Andrade, Cristiano J., Carciofi, Bruno A. M., de Oliveira, Débora

“…Mannosylerythritol-lipids-B (MEL-B) are microbial-produced glycolipids with skincare properties, notably moisturizing, antimelanogenic, antimicrobial, and…”
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Circulating Ang-2 mRNA expression levels: looking ahead to a new prognostic factor for NSCLC [corrected] by Coelho, Ana L, Araújo, António, Gomes, Mónica, Catarino, Raquel, Marques, Agostinho, Medeiros, Rui

“…Non-small cell lung cancer (NSCLC) is the most common cancer and the leading cause of death from cancer worldwide. Antiangiogenic strategies directed towards…”
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The Chemokine CCL6 Promotes Innate Immunity via Immune Cell Activation and Recruitment by Coelho, Ana L, Schaller, Matthew A, Benjamim, Claudia F, Orlofsky, Amos Z, Hogaboam, Cory M, Kunkel, Steven L

“…Septic syndrome is a consequence of innate immune failure. Recent studies showed that the CC chemokine CCL6 enhanced antimicrobial immunity during experimental…”
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Targeting ST2L Potentiates CpG-Mediated Therapeutic Effects in a Chronic Fungal Asthma Model by Ramaprakash, Hemanth, Shibata, Takehiko, Duffy, Karen E, Ismailoglu, Ugur B, Bredernitz, Rachel M, Moreira, Ana Paula, Coelho, Ana L, Das, Anuk M, Fursov, Natalie, Chupp, Geoffrey L, Hogaboam, Cory M

“…IL-33 and its soluble receptor and cell-associated receptor (ST2L) are all increased in clinical and experimental asthma. The present study addressed the…”
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A systemic granulomatous response to Schistosoma mansoni eggs alters responsiveness of bone marrow-derived macrophages to Toll-like receptor agonists by Joshi, Amrita D., Raymond, Tracy, Coelho, Ana L., Kunkel, Steven L., Hogaboam, Cory M.

“…Macrophages play a pivotal role in innate and acquired immune responses to Schistosoma mansoni. Classical (M1) or alternative (M2) activation states of these…”
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Toll-like Receptor 9 Activation Is a Key Mechanism for the Maintenance of Chronic Lung Inflammation by Ito, Toshihiro, Schaller, Matthew, Raymond, Tracy, Joshi, Amrita D, Coelho, Ana L, Frantz, Fabiani G, Carson, William F., IV, Hogaboam, Cory M, Lukacs, Nicholas W, Standiford, Theodore J, Phan, Sem H, Chensue, Stephen W, Kunkel, Steven L

“…Accumulating evidence supports the hypothesis that the continuous host response to a persistent challenge can polarize the cytokine environment toward a Th2…”
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Modeling Idiopathic Pulmonary Fibrosis in Humanized Severe Combined Immunodeficient Mice by Habiel, David M., Espindola, Milena S., Coelho, Ana L., Hogaboam, Cory M.

“…Idiopathic pulmonary fibrosis (IPF) is a fibrotic lung disease of unknown etiopathogenesis with limited therapeutic options. IPF is characterized by an…”
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19q13.11 microdeletion: Clinical features overlapping ectrodactyly ectodermal dysplasia‐clefting syndrome phenotype by Abe, Kikue Terada, Rizzo, Isabela M. P. O., Coelho, Ana L. V., Sakai, Nilo, Carvalho, Daniel R., Speck‐Martins, Carlos E.

“…Key Clinical Message We report a patient who was followed for a long time under an ectrodactyly ectodermal dysplasia‐clefting (EEC) syndrome and was…”
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Targeting MAP3K19 prevents human lung myofibroblast activation both in vitro and in a humanized SCID model of idiopathic pulmonary fibrosis by Jones, Isabelle C., Espindola, Milena S., Narayanan, Rohan, Coelho, Ana L., Habiel, David M., Boehme, Stefen A., Ly, Tai Wei, Bacon, Kevin B., Hogaboam, Cory M.

“…Idiopathic Pulmonary Fibrosis (IPF) is a disease with a devastating prognosis characterized by unrelenting lung scarring. Aberrant activation of lung…”
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Mannosylerythritol lipids: production, downstream processing, and potential applications by de Andrade, Cristiano J, Coelho, Ana LS, Feuser, Paulo E, de Andrade, Lidiane M, Carciofi, Bruno AM, de Oliveira, Débora

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Chemokines provide the sustained inflammatory bridge between innate and acquired immunity by Coelho, Ana L., Hogaboam, Cory M., Kunkel, Steven L.

“…In this review we focus on the role of chemokines in discreet areas of innate immunity and demonstrate that chemokines are key participants to not only the…”
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Phase II Study of Celecoxib with Cisplatin Plus Etoposide in Extensive-Stage Small Cell Lung Cancer by Araújo, António M.F., Mendez, Jose C., Coelho, Ana L., Sousa, Berta, Barata, Fernando, Figueiredo, Ana, Amaro, Teresina, Azevedo, Isabel, Soares, Marta

“…We performed a phase II trial to test whether a cyclooxygenase (COX-2) inhibitor, celecoxib, added to standard first-line combination chemotherapy (CT) and as…”
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Reativação erosiva em cicatriz de movimento de massa, Maciço da Tijuca, RJ by Leão, Otávio M. R., Balesdent, Flavio C., Cruz, Eduardo S., Netto, Ana L. Coelho

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CD4+ T cell cytokine production is influenced by jagged 1 by Schaller, Matthew A, Coelho, Ana L, Lukacs, Nicholas W, Kunkel, Steven L

“…Notch is a promiscuous system consisting of four receptors and five ligands that is important for providing signals to direct cell differentiation in…”
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Topotecan in second-line treatment of small-cell lung cancer--how it works in our daily clinical practice? by Faria, Ana Luísa Lourenço Moreira, Bravo, Emilio Macias, Rocha, Marta Alexandra Silva Soares, Rocha, Isabel Maria Azevedo, Coelho, Ana Luísa Pequeno, Araújo, António Manuel Ferreira

“…Lung cancer is one of the most commonly diagnosed malignancies and it causes more than 1 million deaths each year worldwide. Small-cell lung cancer (SCLC)…”
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19q13.11 microdeletion: Clinical features overlapping ectrodactyly ectodermal dysplasia-clefting syndrome phenotype by Abe, Kikue Terada, Rizzo, Isabela M P O, Coelho, Ana L V, Sakai, Nilo, Carvalho, Daniel R, Speck-Martins, Carlos E

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