Search Results - "Coco, Paola"
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P686: REAL‐WORLD EFFICACY PROFILE OF ASCIMINIB IN AN ITALIAN, MULTI‐RESISTANT CHRONIC‐PHASE CHRONIC MYELOID LEUKEMIA (CP‐CML) PATIENT POPULATION
Published in HemaSphere (08-08-2023)Get full text
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A Phase II, Single-Arm Study of De-Escalation and Treatment-Free Remission in Patients with Chronic Myeloid Leukemia Treated with Nilotinib in First-Line Therapy Followed By a Second Attempt after Nilotinib and Asciminib Combination: Dante Study
Published in Blood (15-11-2022)Get full text
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Full Treatment-Free Remission Outcome in Patients with Chronic Myeloid Leukemia in Chronic Phase Following One Year of Nilotinib De-Escalation: 96-Week Update of Dante Study
Published in Blood (02-11-2023)“…Introduction: Treatment-free remission (TFR) in chronic myeloid leukemia (CML) is achievable and recommended for patients (pts) in sustained deep molecular…”
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Surgery of residual disease following molecular-targeted therapy with imatinib mesylate in advanced/metastatic GIST
Published in Annals of surgery (01-03-2007)“…To explore the role of surgery of residual disease following a period of therapy with imatinib mesylate in advanced gastrointestinal stromal tumors (GIST)…”
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Real-World Analysis of the Clinical and Economic Burden of Later Line in Chronic Myeloid Leukemia Patients in Italy
Published in Blood (23-11-2021)“…Background The use of real-world data in oncology is gaining increasing interest, as it can provide valuable insights into treatments and related outcomes in…”
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The Economic Burden of Chronic Myeloid Leukemia in Patients with Later Lines: Findings from a Real-World Analysis in Italy
Published in Advances in therapy (01-03-2023)“…Introduction Chronic myeloid leukemia (CML) is a hematopoietic myeloproliferative disorder that accounts for 20% of all leukemias of adults. The introduction…”
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Adherence to ruxolitinib, an oral JAK1/2 inhibitor, in patients with myelofibrosis: interim analysis from an Italian, prospective cohort study (ROMEI)
Published in Leukemia & lymphoma (02-01-2022)“…ROMEI, a prospective, observational study in patients with myelofibrosis receiving the oral JAK1/2 inhibitor ruxolitinib in real-world practice, assesses…”
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Real-World Analysis of the Therapeutic Management and Disease Burden in Chronic Myeloid Leukemia Patients with Later Lines in Italy
Published in Journal of clinical medicine (22-06-2022)“…Real world data are becoming a crucial tool to understand how cancer is treated in routine daily practice. This real-world analysis aims to describe the…”
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Dacarbazine in combination with bevacizumab for the treatment of unresectable/metastatic melanoma: a phase II study
Published in Melanoma research (01-06-2015)“…The combined treatment of dacarbazine with an antiangiogenic drug such as bevacizumab may potentiate the therapeutic effects of dacarbazine in metastatic…”
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Patterns of Care, Prognosis, and Survival in Patients with Metastatic Gastrointestinal Stromal Tumors (GIST) Refractory to First-Line Imatinib and Second-Line Sunitinib
Published in Annals of surgical oncology (01-05-2012)“…Background Data regarding the management and outcome of patients with metastatic gastrointestinal stromal tumors (GIST) refractory to 1st-line imatinib and…”
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A Novel Tyrosine-Kinase Selective Inhibitor, Sunitinib, Induces Transient Hypothyroidism by Blocking Iodine Uptake
Published in The journal of clinical endocrinology and metabolism (01-09-2007)“…Context: Sunitinib (sunitinib malate; SU11248; Sutent; Pfizer Inc., New York, NY) is a multitarget inhibitor of tyrosine kinases for the treatment of some…”
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JAK Inhibition with Ruxolitinib in Patients with COVID-19 and Severe Pneumonia: Multicenter Clinical Experience from a Compassionate Use Program in Italy
Published in Journal of clinical medicine (23-08-2021)“…Jak inhibitors are potent anti-inflammatory drugs that have the potential to dampen the hyperactive inflammatory response associated with severe COVID-19. We…”
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Imatinib response in two GIST patients carrying two hitherto functionally uncharacterized PDGFRA mutations: An imaging, biochemical and molecular modeling study
Published in International journal of cancer (15-02-2011)“…Beside the well known “in vivo” and “in vitro” Imatinib resistant D842V mutation in PDGFRA receptor, very few are the information concerning the “in vivo”…”
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