Search Results - "Cockshell, Michaelia P"
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CD36 promotes vasculogenic mimicry in melanoma by mediating adhesion to the extracellular matrix
Published in BMC cancer (02-07-2021)“…Background The formation of blood vessels within solid tumors directly contributes to cancer growth and metastasis. Until recently, tumor vasculature was…”
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BMPR2‐expressing bone marrow‐derived endothelial‐like progenitor cells alleviate pulmonary arterial hypertension in vivo
Published in Respirology (Carlton, Vic.) (01-11-2019)“…ABSTRACT Background and objective Pulmonary arterial hypertension (PAH) is characterized by increased resistance in the distal pulmonary arteries, ultimately…”
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3
Vasculogenic mimicry structures in melanoma support the recruitment of monocytes
Published in Oncoimmunology (31-12-2022)“…The progression of cancer is facilitated by infiltrating leukocytes which can either actively kill cancer cells or promote their survival. Our current…”
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4
Desmoglein-2 is important for islet function and β-cell survival
Published in Cell death & disease (29-10-2022)“…Type 1 diabetes is a complex disease characterized by the lack of endogenous insulin secreted from the pancreatic β-cells. Although β-cell targeted autoimmune…”
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5
The development of tumour vascular networks
Published in Communications biology (22-09-2021)“…The growth of solid tumours relies on an ever-increasing supply of oxygen and nutrients that are delivered via vascular networks. Tumour vasculature includes…”
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Endogenous bystander killing mechanisms enhance the activity of novel FAP-specific CAR-T cells against glioblastoma
Published in Clinical & translational immunology (01-01-2024)“…CAR-T cells are being investigated as a novel immunotherapy for glioblastoma, but clinical success has been limited. We recently described fibroblast…”
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Characterization of a distinct population of circulating human non-adherent endothelial forming cells and their recruitment via intercellular adhesion molecule-3
Published in PloS one (07-11-2012)“…Circulating vascular progenitor cells contribute to the pathological vasculogenesis of cancer whilst on the other hand offer much promise in therapeutic…”
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Interleukin-3 greatly expands non-adherent endothelial forming cells with pro-angiogenic properties
Published in Stem cell research (01-05-2015)“…Circulating endothelial progenitor cells (EPCs) provide revascularisation for cardiovascular disease and the expansion of these cells opens up the possibility…”
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Sphingosine 1‐phosphate is a ligand for peroxisome proliferator‐activated receptor‐γ that regulates neoangiogenesis
Published in The FASEB journal (01-09-2015)“…ABSTRACT Sphingosine 1‐phosphate (S1P) is a bio‐active lipid that can function both extracellularly and intracellularly to mediate a variety of cellular…”
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Platelets disrupt vasculogenic mimicry by cancer cells
Published in Scientific reports (03-04-2020)“…Tumour vasculature supports the growth and progression of solid cancers with both angiogenesis (endothelial cell proliferation) and vasculogenic mimicry (VM,…”
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Recruitment and proliferation of CD4+ T cells in synovium following adoptive transfer of adjuvant-induced arthritis
Published in International immunology (01-06-2006)“…Adjuvant-induced arthritis can be transferred to naive Dark Agouti (DA) strain (DA.CD45.1) rats by thoracic duct (TD) lymphocytes. Disease can be re-induced in…”
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Porous Silicon-Based Cell Microarrays: Optimizing Human Endothelial Cell-Material Surface Interactions and Bioactive Release
Published in Biomacromolecules (14-11-2016)“…Porous silicon (pSi) substrates are a promising platform for cell expansion, since pore size and chemistry can be tuned to control cell behavior. In addition,…”
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Study of the Structure of Hyperbranched Polyglycerol Coatings and Their Antibiofouling and Antithrombotic Applications
Published in Advanced healthcare materials (01-10-2024)“…While blood‐contacting materials are widely deployed in medicine in vascular stents, catheters, and cannulas, devices fail in situ because of thrombosis and…”
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14
Attachment of endothelial colony-forming cells onto a surface bearing immobilized anti-CD34 antibodies: Specific CD34 binding versus nonspecific binding
Published in Biointerphases (01-05-2022)“…Cardiovascular disease is a leading cause of death worldwide; however, despite substantial advances in medical device surface modifications, no synthetic…”
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A non-canonical role for desmoglein-2 in endothelial cells: implications for neoangiogenesis
Published in Angiogenesis (London) (01-10-2016)“…Desmogleins (DSG) are a family of cadherin adhesion proteins that were first identified in desmosomes and provide cardiomyocytes and epithelial cells with the…”
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Affinity Binding of EMR2 Expressing Cells by Surface-Grafted Chondroitin Sulfate B
Published in Biomacromolecules (12-06-2017)“…The propensity of glycosaminoglycans to mediate cell–cell and cell–matrix interactions opens the door to capture cells, including circulating blood cells, onto…”
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Surface-Grafted Hyperbranched Polyglycerol Coating: Varying Extents of Fouling Resistance across a Range of Proteins and Cells
Published in ACS applied bio materials (15-06-2020)“…Hyperbranched polyglycerol (HPG) was previously investigated as a nonfouling hydrophilic grafted layer on biomaterial surfaces, analogous to the well-known…”
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Replica moulded poly(dimethylsiloxane) microwell arrays induce localized endothelial cell immobilization for coculture with pancreatic islets
Published in Biointerphases (01-01-2019)“…PolyJet three-dimensional (3D) printing allows for the rapid manufacturing of 3D moulds for the fabrication of cross-linked poly(dimethylsiloxane) microwell…”
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Circulating human progenitor cells — The sentinels of vascular repair?
Published in Vascular pharmacology (01-05-2012)Get full text
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Over-Expression of Sphingosine Kinase-1 Enhances a Progenitor Phenotype in Human Endothelial Cells
Published in Microcirculation (New York, N.Y. 1994) (01-10-2011)“…Please cite this paper as: Barrett, Parham, Pippal, Cockshell, Moretti, Brice, Pitson, and Bonder (2011). Over‐Expression of Sphingosine Kinase‐1 Enhances a…”
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